- Trimeprazine
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Cas Database |
| Name |
Trimeprazine |
EINECS | 201-577-3 |
| CAS No. | 84-96-8 | Density | 1.203 g/cm3 |
| PSA | 31.78000 | LogP | 4.55200 |
| Solubility | 0.942 mg/L in water | Melting Point |
68 ºC |
| Formula | C18H22 N2 S | Boiling Point | 420.3°Cat760mmHg |
| Molecular Weight | 298.452 | Flash Point | 208°C |
| Transport Information | N/A | Appearance | Light Yellow Solid |
| Safety | Poison by ingestion and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx and SOx. | Risk Codes | R20/21/22; R36/37/38 |
| Molecular Structure |
|
Hazard Symbols |
 Xn
|
| Synonyms |
Phenothiazine,10-[3-(dimethylamino)-2-methylpropyl]- (6CI,8CI); (?à)-Alimemazine; (?à)-Trimeprazine; 10-(2-Methyl-3-dimethylaminopropyl)phenothiazine;10-[3-(Dimethylamino)-2-methylpropyl]phenothiazine; Alimemazine; Alimezine;Bayer 1219; Methylpromazine; Teralen; Teralene; Trimeprazine; dl-Trimeprazine |
Article Data | 6 |
Trimeprazine Chemical Properties
Product Name: Alimemazine (CAS NO.84-96-8)
Molecular Formula: C18H22N2S
Molecular Weight: 298.45g/mol
Mol File: 84-96-8.mol
Einecs: 201-577-3
Melting Point: 68°C
Boiling point: 420.3 °C at 760 mmHg
Flash Point: 208 °C
Density: 1.114 g/cm3
Water Solubility: 0.942 mg/L
Surface Tension: 43.4 dyne/cm
Enthalpy of Vaporization: 67.41 kJ/mol
Vapour Pressure: 2.84E-07 mmHg at 25°C
XLogP3: 4.7
H-Bond Donor: 0
H-Bond Acceptor: 2
Trimeprazine Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intravenous | 33mg/kg (33mg/kg) | Psychopharmacology Service Center, Bulletin. Vol. 2, Pg. 17, 1963. | |
| mouse | LD50 | oral | 300mg/kg (300mg/kg) | BEHAVIORAL: ANTIPSYCHOTIC | Developments in Neuroscience Vol. 7, Pg. 45, 1980. |
| mouse | LD50 | subcutaneous | 300mg/kg (300mg/kg) | Gekkan Yakuji. Pharmaceuticals Monthly. Vol. 9, Pg. 759, 1967. | |
| rat | LD50 | intravenous | 35mg/kg (35mg/kg) | Acta Neurologia et Psychiatrica Belgica. Vol. 61, Pg. 669, 1961. | |
| rat | LD50 | oral | 210mg/kg (210mg/kg) | Acta Neurologia et Psychiatrica Belgica. Vol. 61, Pg. 669, 1961. |
Trimeprazine Safety Profile
Poison by ingestion and intravenous routes. When heated to decomposition it emits very toxic fumes of NOx and SOx.
Trimeprazine Specification
Alimemazine ,its CAS NO. is 84-96-8,the synonyms is n,n,2-Trimethyl-3-phenothiazin-10-yl-propan-1-amine ; Trimeprazine ; alimemazine ; 10-[2-Methyl-3-(dimethylamino)propyl]phenothiazine ; 10-[3-(Dimethylamino)-2-methylpropyl]phenothiazine ; 10H-Phenothiazine-10-propanamine, N,N,beta-trimethyl- ; Alimezine ; Bayer 1219 .
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