Reference

3-Methoxybenzeneacetamides

3-Methoxybenzeneacetamides. Murayama, Masao; Murai, Hiromu; Yoshimoto, Yoshihiko; Kunimoto, Katsutoshi; Ohata, Katsuya (Nippon Shinyaku Co., Ltd., Japan). Japan. Kokai JP 52005729 17 Jan 1977 Showa, 2 pp. (Japanese). (Japan). CODEN: JKXXAF. CLASS: IC: C07C103-26. APPLICATION: JP 75-82569 3 Jul 1975. DOCUMENT TYPE: Patent CA Section: 25 (Noncondensed Aromatic Compounds) Benzeneacetamides I (R = Me2CH, Ph, 4-ClC6H4) were prepd. by conversion of acids II to chlorides followed by reaction with aq. NH3. Thus, 3.0 g II (R = Me2CH) in C6H6 was heated with SOCl2 1 h, concd., and 28% aq. NH3 added to ppt. 62790-23-2 which is the cas registry number of some chemical is mentioned. 70% I (R = Me2CH). I have antiinflammatory and analgesic activities. I (R = 4-ClC6H4) [LD50 = >1600 mg/kg (i.p.) in rats] gave 40% inhibition in rat carrageenan edema inhibition test at 100 mg/kg (p.o.). .

Study on explosion and fire danger of drugs

Study on explosion and fire danger of drugs. Marasanov, V. A.; Chashchin, I.In this study， 78-96-6 and 123-03-5 are also used. P.; Rapoport, G. A.; Chernyavskii, G. P. (USSR). Sb. Annot. Nauchno-Issled. Rab. - Tomsk. Politekh. Inst., 6, 117-18 (Russian) 1975. CODEN: SANIDK. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) The min. energy of ignition, min. concn. limit for inflammation, spontaneous combustion temp., flash-point of the products, and electroconductivity were detd. for aerosols of aspirin [50-78-2], hydroxymethylated levomycetin, threamine [78-96-6], anesthesin [94-09-7], salicylic acid [69-72-7], nicotinic acid [59-67-6], isoxazole carboxylic acid [61193-22-4], cetylpyridinium chloride [123-03-5], and phenylacetamide [103-81-1]. The last 4 compds. were the most flammable. .