Products Categories
| CAS No.: | 108-01-0 |
|---|---|
| Name: | N,N-Dimethylethanolamine |
| Article Data: | 101 |
| Molecular Structure: | |
|
|
|
| Formula: | C4H11NO |
| Molecular Weight: | 89.1374 |
| Synonyms: | (2-Hydroxyethyl)dimethylamine;(Dimethylamino)ethanol;(N,N-Dimethylamino)ethanol;2-(Dimethylamino)ethanol;2-(Dimethylamino)ethyl alcohol;2-(N,N-Dimethylamino)ethanol;Amietol M 21;Dimethyl(2-hydroxyethyl)amine;Dimethyl(hydroxyethyl)amine;Dimethylethanolamine;Dimethylmonoethanolamine;N,N-Dimethyl(2-hydroxyethyl)amine;N,N-Dimethyl-2-aminoethanol;N,N-Dimethyl-N-(b-hydroxyethyl)amine;N,N-Dimethyl-b-hydroxyethylamine;N-(2-Hydroxyethyl)-N,N-dimethylamine;N-(2-Hydroxyethyl)dimethylamine;b-Dimethylaminoethyl alcohol;b-Hydroxyethyldimethylamine; |
| EINECS: | 203-542-8 |
| Density: | 0.897 g/cm3 |
| Melting Point: | -70 °C |
| Boiling Point: | 135 °C at 760 mmHg |
| Flash Point: | 40.6 °C |
| Solubility: | miscible in water |
| Appearance: | clear to pale yellow liquid |
| Hazard Symbols: |
 C
|
| Risk Codes: | 10-20/21/22-34 |
| Safety: | 25-26-36/37/39-45 |
| Transport Information: | UN 2051 8/PG 2 |
| PSA: | 23.47000 |
| LogP: | -0.45970 |
- 144851-82-1METHYL2-AMINO-3-FLUOROBENZOATE
- 483366-12-7(2S,4R)-1-Boc-2-cyano-4-hydroxypyrrolidine
- 173606-50-3BOC-10-AMINODECANOIC ACID
- 361456-36-2METHYL (R)-(+)-ISOCYANATO-3-PHENYLPROPI&
- 5156-58-1N-(1-Benzyl-4-pipperidinyl)-N-phenylpropanamide HCl
- 81281-59-67-Benzylideneaminotheophylline
- 50288-62-5threo-Phenyl-2-piperidyl acetamide
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 47087-37-6Z-D-Glu-OMe
- 1219080-61-1IMIDAZOLE-2-BORONIC ACID
- 26062-79-3Poly(diallyldimethylammonium chloride)
- 109-94-4Ethyl formate
- 10101-89-0Trisodium phosphate dodecahydrate
- 110-26-9N,N'-Methylenebisacrylamide
- 504-63-21,3-Propanediol
- 83-67-01H-Purine-2,6-dione,3,7-dihydro-3,7-dimethyl-
- 32315-10-9Triphosgene
- 109-97-7Pyrrole
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
- Total:32 Page 1 of 1 1
What can I do for you?
Get Best Price
Specification
The CAS registry number of N,N-Dimethylethanolamine is 108-01-0. Its EINECS registry number is 203-542-8. The IUPAC name is 2-(dimethylamino)ethanol. In addition, the molecular formula is C4H11NO. What's more, it is an antidepressive agent that has also been used in the treatment of movement disorders. It can be used as a raw material for resin, medicine, dyes and paint solvents. And it is used as a intermediate in the manufacture of dyes, fiber treating agent, medicine and anticorrosive additives.
Physical properties about N,N-Dimethylethanolamine are: (1)ACD/LogP: -0.328; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -3.19; (4)ACD/LogD (pH 7.4): -1.68; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 1.00; (8)ACD/KOC (pH 7.4): 1.00; (9)#H bond acceptors: 2; (10)#H bond donors: 1; (11)#Freely Rotating Bonds: 3; (12)Index of Refraction: 1.433 ; (13)Molar Refractivity: 25.837 cm3; (14)Molar Volume: 99.322 cm3; (15)Polarizability: 10.242 10-24cm3; (16)Surface Tension: 30.6580009460449 dyne/cm; (17)Density: 0.897 g/cm3; (18)Flash Point: 40.556 °C; (19)Enthalpy of Vaporization: 43.395 kJ/mol; (20)Boiling Point: 134.999 °C at 760 mmHg; (21)Vapour Pressure: 3.39299988746643 mmHg at 25°C
Preparation of N,N-Dimethylethanolamine: it can be prepared by dimethylamine and epoxyethane through ammoniation reaction. And then after a series of distillation, rectification and dehydration you can get the desired product.
Uses of N,N-Dimethylethanolamine: it can react with (2-chloro-ethyl)-dimethyl-amine to get bis-(2-dimethylamino-ethyl)-ether. This reaction will need reagent 50 percent NaOH, catalyst Adogen 464 and solvent tetrahydrofuran. The reaction time is 6 hours by heating. The yield is about 35%.
When you are using this chemical, please be cautious about it as the following:
This chemical is flammable and can cause burns. And it is harmful by inhalation, in contact with skin and if swallowed. When you are using it, wear suitable protective clothing, gloves and eye/face protection and avoid contact with eyes. In case of contact with eyes, rinse immediately with plenty of water or soap-suds and seek medical advice. And in case of accident or if you feel unwell, seek medical advice immediately (show label where possible).
You can still convert the following datas into molecular structure:
(1)SMILES: CN(C)CCO
(2)InChI: InChI=1/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3
(3)InChIKey: UEEJHVSXFDXPFK-UHFFFAOYAY
The toxicity data is as follows:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LDLo | intraperitoneal | 450mg/kg (450mg/kg) | Proceedings of the Society for Experimental Biology and Medicine. Vol. 85, Pg. 642, 1954. | |
| mouse | LC50 | inhalation | 3250mg/m3 (3250mg/m3) | SENSE ORGANS AND SPECIAL SENSES: CONJUNCTIVE IRRITATION: EYE BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD BRAIN AND COVERINGS: RECORDINGS FROM SPECIFIC AREAS OF CNS | Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. Vol. 14(11), Pg. 52, 1970. |
| mouse | LD50 | intraperitoneal | 234mg/kg (234mg/kg) | BEHAVIORAL: ATAXIA | Journal of Pharmacology and Experimental Therapeutics. Vol. 94, Pg. 249, 1948. |
| mouse | LD50 | subcutaneous | 961mg/kg (961mg/kg) | LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES BEHAVIORAL: TREMOR BEHAVIORAL: COMA | Naunyn-Schmiedeberg's Archiv fuer Experimentelle Pathologie und Pharmakologie. Vol. 225, Pg. 428, 1955. |
| rabbit | LD50 | skin | 1370uL/kg (1.37mL/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 4, Pg. 119, 1951. | |
| rat | LC50 | inhalation | 1641ppm/4H (1641ppm) | SENSE ORGANS AND SPECIAL SENSES: LACRIMATION: EYE BEHAVIORAL: ATAXIA LUNGS, THORAX, OR RESPIRATION: DYSPNEA | Fundamental and Applied Toxicology. Vol. 9, Pg. 512, 1987. |
| rat | LD50 | intraperitoneal | 1080mg/kg (1080mg/kg) | Toxicology and Applied Pharmacology. Vol. 12, Pg. 486, 1968. | |
| rat | LD50 | oral | 2gm/kg (2000mg/kg) | Zeitschrift fuer die Gesamte Hygiene und Ihre Grenzgebiete. Vol. 20, Pg. 393, 1974. |