Reference

Cis-1,2-Diaminocyclohexane platinum complexes

Cis-1,2-Diaminocyclohexane platinum complexes. (Fabrica de Productos Quimicos y Farmaceuticos Abello S. A., Spain). Belg. BE 898614 A1 2 May 1984, 16 pp. (French). (Belgium). CODEN: BEXXAL. ICI: A61. APPLICATION: BE 21-161 5 Jan 1984. DOCUMENT TYPE: Patent CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1, 49 cis-1,2-Diaminocyclohexane platinum (II) complexes (I, X and Y = sulfates, sulfonates, nitrates, carboxylates, etc.) are prepd. for use as neoplasm inhibitors. Cis-dichloro-1,2-diaminocyclohexane platinum [52691-24-4] was treated with AgNO3 and the resulting dinitrate complex [81473-15-6] obtained was further treated with 3-bromopyruvic acid [1113-59-3] to yield cis-bis(3-bromopyruvato)-1,2-diaminocyclohexaneplatinum [92389-55-4]. The yield was 70%.

Enzymic production of aminoethylcysteine ketimine

Enzymic production of aminoethylcysteine ketimine. Chiaraluce, Roberta; Nardini, Mirella; Dupre, Silvestro; Ricci, Giorgio; Cavallini, Doriano (Inst. Biol. Chem., Univ. Roma "La Sapienza", Rome, Italy). IRCS Med. Sci.: Libr. Compend. 1113-59-3 and 89648-14-6 are cas registry numbers of chemicals which are used as reagents here., 11(12), 1119-20 (English) 1983. CODEN: IRLCDZ. ISSN: 0305-6651. DOCUMENT TYPE: Journal CA Section: 7 (Enzymes) Section cross-reference(s): 6 Aminoethylcysteine ketimine (I) was produced on incubation of pantetheine or S-pyruvoyl pantetheine with horse kidney homogenate. The I-forming activity copurified from the homogenate with cysteamine-forming activity. The enzyme responsible for I formation in the horse kidney apparently is pantetheinase. .