Reference

Pseudomonas putida cell multiplication inhibition test: Weibull dose-response curve of several trifluoromethylbenzene derivatives

Pseudomonas putida cell multiplication inhibition test: Weibull dose-response curve of several trifluoromethylbenzene derivatives. Dacarro, C.; Baldi, M.; Bonferoni, M. C.; Riganti, V. (Ist. Farmacol., Univ. Pavia, Pavia 27100, Italy). Ig. Mod.Several substances with their cas registry numbers 121-50-6 and 393-77-1 may be metioned in this study., 86(3), 223-39 (Italian) 1986. CODEN: IGMPAX. ISSN: 0019-1655. DOCUMENT TYPE: Journal CA Section: 4 (Toxicology) The toxicity of 8 derivs. of trifluoromethylbenzene [98-08-8] was detd. by multiplication inhibition of P. putida. Most toxic were 3,5-dinitro-4-chlorotrifluoromethylbenzene (I) [393-75-9], 2-nitrotrifluoromethylbenzene [384-22-5], and 5-amino-2-chlorotrifluoromethylbenzene [320-51-4]; moderately toxic was 3-nitro-4-chlorotrifluoromethylbenzene [121-17-5]; and least toxic were 3-nitrotrifluoromethylbenzene [98-46-4], 3,5-dinitro-4-hydroxytrifluoromethylbenzene [393-77-1], 3-amino-4-chlorotrifluoromethylbenzene [121-50-6], and 2-aminotrifluoromethylbenzene [88-17-5]. The mechanism of the toxicity is discussed. .

Potential antimicrobial agents: Trifluoromethyl-10H-phenothiazines and ribofuranosides

Potential antimicrobial agents: Trifluoromethyl-10H-phenothiazines and ribofuranosides. Singh, Girwar; Kumar, Neeraj; Yadav, Ashok K.; Mishra, A. K. ( Department of Chemistry, University of Rajasthan, Jaipur 302004, India). Heteroatom Chemistry, 14(6), 481-486 (English) 2003 John Wiley & Sons, Inc. CODEN: HETCE8. ISSN: 1042-7163. DOCUMENT TYPE: Journal CA Section: 10 (Microbial, Algal, and Fungal Biochemistry) Section cross-reference(s): 28 The zinc salts of substituted 2-amino benzenethiols, on condensation with 2-chloro-3-nitro-5-trifluoromethyl benzene, in presence of sodium acetate and ethanol and subsequent formylation gave the corresponding 2-formamido-substituted diphenylsulfides. From them substituted 2-trifluoromethyl-10 H-phenothiazines have been synthesized via Smiles rearrangement. Ribofuranosides a- and b- anomers were synthesized by the condensation of phenothiazines with sugar in toluene in presence of SnCl4 at 0°C and 155-160°C, resp. The fluoromethylphenothiazines and their ribofuranosides were screened for antimicrobial activity against bacteria and fungi and showed fairly good activity.Except for chemicals metioned above, 121-17-5 is also used. .