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Detail of "139755-83-2"

  • MSDS Download
  • CAS Number:
  • 139755-83-2
  • Name:

  • Sildenafil

  • Molecular Structure:
  • Formula:
  • C22H30N6O4S
  • Molecular Weight:
  • 474.58
  • Synonyms:
  • 4-[2-ethoxy-5-(4-methylpiperazin-1-yl)sulfonyl-phenyl]-9-methyl-7-propyl-3,5,8,9-tetrazabicyclo[4.3.0]nona-3,7,10-trien-2-one;Piperazine,1-[[3-(4,7-dihydro-1-methyl-7- oxo-3-propyl-1H-pyrazolo[4,3-d]pyrimidin- 5-yl)-4-ethoxyphenyl]sulfonyl]-4-methyl-;Serum Albumin Iodine;Sildenafil Mesylate;Hongdenafil (Acetildenafil);
  • Density:
  • 1.39 g/cm3
  • Melting Point:
  • 187-189 ºC
  • Boiling Point:
  • 672.4 ºC at 760 mmHg
  • Flash Point:
  • 360.5 ºC
  • Solubility:
  • Slightly soluble in water, methanol; very slightly soluble in ethanol, chloroform
  • Appearance:
  • White crystalline powder
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CAS No.139755-83-2 SildenafilCompetitive Product

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  Appearance:white crysta...

5-[2-Ethoxy-5-(4-methylpiperazin-1-yl-sulphonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazol[4,3d]pyrimidin-7-one Chemical name :Sildenafil Molecular Formula:C22H30N6O4S

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CAS No.139755-83-2 Sildenafil

Name Sildenafil Synonyms 5-[2-Ethoxy-5-(4-methylpiperazin-1-yl-sulphonyl)phenyl]-1-methyl-3-n-propyl-1,6-dihydro-7H-pyrazol[4,3d]pyrimidin-7-one Molecular Formula C22H30N6O4S Molecular Weight 474.58 CAS Registry Number 139755-83-2

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CAS No.139755-83-2 Sildenafil

Sildenafil Character: sildenafil citrate, sildenafil, viagra; cure ED(Erectile Dysfunction); 150-180mg/day Property: white to off-white crystalline powder, odorless, bitter taste, insoluble in water and ethanol. Function: sildenafil is a drug used to treat erection difficult

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Androgen Name: China Sildenafil citrate white powder trade name: viagra MF: C22H30N6O4S MW: 474.58 CAS: 139755-83-2 Content:99.5% Sildenafil citrate Solubility: Slightly soluble in water, methanol; very slightly soluble in ethanol, chloroform Appearance: White crystalli

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Reference

Effects of sildenafil on nocturnal penile tumescence and rigidity in normal men: randomized, placebo-controlled, crossover study
Effects of sildenafil on nocturnal penile tumescence and rigidity in normal men: randomized, placebo-controlled, crossover study. Rochira, Vincenzo; Granata, Antonio R. M.; Balestrieri, Antonio; Madeo, Bruno; Carani, Cesare (Department of Internal Medicine, Chair of Endocrinology, University of Modena, Modena, Italy). Journal of Andrology, 23(4), 566-571 (English) 2002 American Society of Andrology, Inc. CODEN: JOAND3. ISSN: 0196-3635. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) The effects of sildenafil on sleep-related erections were studied in 44 adult, healthy men not affected by erectile dysfunction (mean age 39.3 yr). Sildenafil (50 mg) and placebo were administered 1 h before bedtime. The following parameters of sleep-related erections, after taking sildenafil or placebo, were analyzed: total no. of valid erections, total duration of rigidity 370% of a tightening force of 2.8 N applied by the recording device, total duration of increase in penile circumference 330 mm, max. rigidity, mean of max. rigidity, and max. increase of tumescence. Apart from the max. increase of tumescence, all the parameters analyzed were higher after sildenafil than after placebo administration during the 1st 4 h of monitoring in all the subjects. All the parameters were higher after sildenafil than after placebo administration during the whole 8 h of monitoring in 25 of the 44 subjects who slept 38 h. Comparing both the 1st and the 2nd 4 h in the 25 of the 44 subjects who slept 38 h, all the parameters were significantly higher after sildenafil than after placebo administration, apart from max. rigidity and mean of max. 139755-83-2 and 10102-43-9 which are cas registry numbers of substances are two of reagents here. rigidity during the 1st 4 h. Sildenafil, administered at bedtime, is apparently effective in improving sleep-related erections in normal men, indirectly confirming that the NO pathway is crucial in the physiol. of erections during sleep. The effect of sildenafil lasts for 8-9 h after its administration. .
Sildenafil (Viagra) in kidney transplant recipients with erectile dysfunction
Sildenafil (Viagra) in kidney transplant recipients with erectile dysfunction. Espinoza, R.; Melchor, J. L.; Gracida, C. (Transplant Service, Especialidades Hospital, C.M.N. SIGLO XXI, Mexico City, Mex.). Transplantation Proceedings, 34(1), 408-409 (English) 2002 Elsevier Science Inc. CODEN: TRPPA8. ISSN: 0041-1345. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) The incidence of erectile dysfunction in men with kidney transplant was 48.9%. The causative factors were org., and sildenafil was effective in 26 of the 28 patients treated. The index of erectile function returned almost to the normal range. 139755-83-2 and 171599-83-0 are just another two chemicals used in this study. The drug was well tolerated. .
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