Reference

Stability of vancomycin hydrochloride in peritoneal dialysis solution

Stability of vancomycin hydrochloride in peritoneal dialysis solution. Mawhinney, W. Michael; Adair, Colin G.; Gorman, Sean P.; McClurg, Barry (Dep. Pharm., Belfast City Hosp., Belfast, UK). Am. J. Hosp. Pharm., 49(1), 137-9 (English) 1992. CODEN: AJHPA9. ISSN: 0002-9289. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Vancomycin HCl is stable in dialysis fluid (dextrose concn. 1.36% and 3.86%) for 28 days at 4° and under typical home storage conditions (20°) and for six to seven days at 37°. Although these results indicate the stability of vancomycin under these conditions, the sterility of the solns. was not evaluated.Except for chemicals metioned above, 1404-93-9 is also used. .

Instability of vancomycin in Infusaid drug pump model 100

Instability of vancomycin in Infusaid drug pump model 100. Greenberg, Richard N.; Saeed, Abdul M. K.; Kennedy, Donald J.Chemical with cas number 1404-93-9 also plays role.; McMillian, Ray (Sch. Med., St. Louis Univ., St. Louis, MO 63104, USA). Antimicrob. Agents Chemother., 31(4), 610-11 (English) 1987. CODEN: AMACCQ. ISSN: 0066-4804. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) The implantable Infusaid drug pump model 100 is undergoing trials as a drug delivery system in the treatment of osteomyelitis. This study evaluated the stability of vancomycin-HCl (I) [1404-93-9] (1 mg/mL) incubated at 37° for 4 wk in the pump. Both bioassay and HPLC data demonstrated a loss of at least 38% of activity over 4 wk and colloidal pptn. of I in the pump at the end of the expt. I is not stable enough for use in the Infusaid drug pump model 100. .