Reference

Arthropod repellent

Arthropod repellent. Smolanoff, Joel Robert (Rohm and Haas Co., USA). Ger. Offen. DE 2756360 29 Jun 1978, 56 pp.Several reagents such as 2043-61-0 is used here. (German). (Germany). CODEN: GWXXBX. CLASS: IC: A01N009-22. PRIORITY: US 76-751932 17 Dec 1976. DOCUMENT TYPE: Patent CA Section: 5 (Agrochemicals) Section cross-reference(s): 27, 28 Insect repellents contain cyclic amines I (R = alkyl, alkoxy, alkoxycarbonylalkyl, CN; R1 = H, alkyl, alkenyl; R2 = H, alkyl, cycloalkyl, alkoxycarbonyl, aralkyl, aryl or CR1R2 = cycloaliph; R3 = H, alkyl, C1-5 hydroxyalkyl, alkoxycarbonyl, alkoxycarbonylalkyl, carbamoyl, thiocarbamoyl; m = 0-2; n,n' = 1,2). Cyclohexanecarboxaldehyde [2043-61-0] was cyanoethylated and ketalized to give II [67625-75-6] which was reduced by LiAlH4 and treated with acid and then base to give III [67625-76-7]. III at 3-5 mg/cm2 applied to guinea pigs repelled houseflies for 4 days and yellow fever mosquitoes for 7 days. .

Carbonyl homologation with

Carbonyl homologation with .alpha. substitution. A new synthesis of 4,4-disubstituted 2-cyclopentenones. Martin, Stephen F.; Chou, Ta-Shue; Payne, Claud W. (Dep. Chem., Univ. Texas, Austin, Tex., USA). J. Org. Chem., 42(14), 2520-3 (English) 1977. CODEN: JOCEAH. DOCUMENT TYPE: Journal CA Section: 24 (Alicyclic Compounds) Section cross-reference(s): 23 Cyclohexanecarboxaldehydes I (R = H, Me; R1 = H, Me, CMe3) were cyclized in concd. H2SO4 at 0.degree. There are some commonly used reagents like 62167-30-0 in this article. to spiro[4.5]dec-3-en-2-ones II. Cyclohexanones with an (aminomethyl)phosphonate gave enamines which were hydrolyzed and alkenylated by CH2:CBrCH2Br to give I. Similarly, 3-heptanone was converted to 4-butyl-4-ethyl-2-cyclopentenone. .