Reference

1,4-Cyclohexanediamine derivatives, procedure for their preparation, and their use as agrochemical fungicides

1,4-Cyclohexanediamine derivatives, procedure for their preparation, and their use as agrochemical fungicides. Rentzea, Costin; Sauter, Hubert; Goetz, Norbert; Graf, Hermann; Ammermann, Eberhard; Pommer, Ernst Heinrich (BASF A.-G. , Fed. Rep. Ger.). Ger. Offen. DE 3612831 A1 22 Oct 1987, 13 pp. (Germany) CODEN: GWXXBX. CLASS: ICM: C07C093-06. ICS: C07C093-08; C07D307-91; A01N033-08; A01N043-12. APPLICATION: DE 86-3612831 16 Apr 1986. DOCUMENT TYPE: Patent CA Section: 24 (Alicyclic Compounds) Section cross-reference(s): 5, 25, 27 Cyclohexanediamines I [Ar = substituted 3-dibenzofuranyl, 1- and 2-naphthyl, Ph (un)substituted with halo, CF3, alkyl, alkoxy, NO2, or cyano; R1, R2 independently = H, Me, Et; R3, R4 independently = Me, Et, Pr, CHMe2, Bu, CHMeEt, CH2CHMe2, CMe3, tert-amyl; A = hydrocarbon chain (un)substituted with 1-3 alkyl; n = 0-4] and their salts, useful as agrochem. fungicides, were prepd. by 2 methods. 1,4-Diamino-2,6-diisopropylcyclohexane was successively treated with CaO and 2-ClC6H4OCH2CH2Br and the mixt. stirred 10 h at 110° to give 1-amino-4-[2-(2-chlorophenoxy)ethylamino]-2,6-diisopropylcyclohexane . I [Ar = 7-chlorodibenzofuran-3-yl, n = 0, A = (CH2)3, R3 = R4 = CHMe2] controlled 97% Botrytis cinerea on sweet peppers at 0.05%, whereas a known fungicide gave 70% control. Nine fungicidal formulations were given.

Monoclonal antibodies specific for crack cocaine metabolites, a cell line producing the same, and crack cocaine conjugates

Monoclonal antibodies specific for crack cocaine metabolites, a cell line producing the same, and crack cocaine conjugates. Lu, Natalie T. (USA ). U.S. Pat. Appl. Publ. US 2005026303 A1 3 Feb 2005,8 pp. (English). (United States of America).In this article, certain chemicals are used. Some of their cas registry numbers are 124-09-4 and 3114-70-3 CODEN: USXXCO. CLASS: ICM: A61K039-395. ICS: C12N005-06; C07K016-18; G01N033-543. NCL: 436518000; 530388100; 435326000. APPLICATION: US 2003-629749 30 Jul 2003. DOCUMENT TYPE: Patent CA Section: 4 (Toxicology) Section cross-reference(s): 15 A monoclonal antibody, and a cell line capable of producing the same, has been produced with the ability to detect the primary metabolites generated from the pyrolysis of smokeable, or "crack", cocaine. This monoclonal antibody, while being highly specific for anhydroecgonine Me ester (AEME) and ecgonidine (ECD), does not cross-react at a significant level with the primary cocaine metabolites of powd. or injected cocaine. Crack cocaine metabolite-protein conjugates with or without linkers are used to immunize animals for the prodn. of monoclonal antibodies. The antibodies can be used in immunoassays to discriminate between the use of crack cocaine and the powd. or injected forms. .