Reference

Poly(arylene ether sulfones) by polyetherification

Poly(arylene ether sulfones) by polyetherification. 2. Polycondensations. Attwood, T. E.; Barr, D. A.; King, T.; Newton, A. B.; Rose, J. B. (Plast. Div., Imp. Chem. Ind. Ltd., Welwyn Garden City, Engl.). Polymer, 18(4), 359-64 (English) 1977. CODEN: POLMAG. ISSN: 0032-3861. DOCUMENT TYPE: Journal CA Section: 35 (Synthetic High Polymers) Polysulfones, e.g. I and II, were prepd. by melt and soln. polycondensation of 1 or 2 of 11 alkali metal halophenylsulfonylphenoxides and 4 copolymers were prepd. by polycondensation of 4-halophenylsulfonyl compds. with dihydric phenols in the presence of KF. The ease of formation of high mol. wt. polymers depended on functional group reactivities. Branched polysulfone [26220-27-9] samples were prepd. by polycondensation of K 4-methoxyphenylsulfonyl-4'-phenoxide and K 4-fluorophenylsulfonyl-4'-phenoxide with 2,4,4'-trifluorodiphenyl sulfone [64075-08-7], prepd. by AlCl3-catalyzed reaction of 4-fluorobenzenesulfonyl chloride [349-88-2] and m-difluorobenzene [372-18-9].

Study on the new preparation of fluconazole

All Rights Reserved. Study on the new preparation of fluconazole. Wang, Jian-xiang (Taizhou Polytechnical Institute Jiangsu, Taizhou 225300, Peop. Rep. China). Zhongguo Xiandai Yingyong Yaoxue, 23(1), 35-37 (Chinese) 2006 Zhongguo Xiandai Yingyong Yaoxue Zazhi Bianji Weiyuanhui. CODEN: ZXYYAI. ISSN: 1007-7693. DOCUMENT TYPE: Journal CA Section: 28 (Heterocyclic Compounds (More Than One Hetero Atom)) OBJECTIVE To improve the synthesis of fluconazole. METHODS Fluconazole was prepd. 79-04-9 and 372-18-9 are cas registry numbers of chemicals which are used as reagents here. after three steps reaction with m-difluorobenzenes as starting material and 1H-1,2,4-triazole was replaced by 4-amino-1H-1,2,4-triazole. The phase transfer catalysis and ultrasonic method have been adopted sep. in this technol. RESULTS The m.p. of the product was in the range of 137°C and 141°C and the overall yield was 50%. .