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Detail of "52-24-4"

  • MSDS Download
  • CAS Number:
  • 52-24-4
  • Name:

  • Aziridine,1,1',1''-phosphinothioylidynetris-

  • Superlist Name:
  • Triethylenethiophosphoramide
  • Molecular Structure:
  • Formula:
  • C6H12N3PS
  • Molecular Weight:
  • 189.22
  • Synonyms:
  • Phosphinesulfide, tris(1-aziridinyl)- (7CI,8CI);1,1',1''-Phosphinothioylidynetrisaziridine;AI 3-24916;CBC 806495;Girostan;N,N',N''-Triethylenethiophosphoramide;N,N',N''-Triethylenethiophosphortriamide;NCI C01649;NSC 6396;Oncotepa;Oncothio-tepa;Oncotiotepa;Phosphorothioic acid triethylenetriamide;Phosphorothioic triamide, N,N',N''-tri-1,2-ethanediyl-;SK 6882;STEPA;TESPA;TSPA;Tespamin;Tespamine;Thio-Tep;Thio-Tepa S;Thiofozil;Thiophosphamide;Thiophosphoramide, N,N',N''-tri-1,2-ethanediyl-;Thioplex;Thiotef;Thiotepa;Tio-TEF;Tiofosfamid;Tiofosyl;Tiofozil;Triethylenethiophosphoramide;Tris(1-aziridinyl)phosphine sulfide;
  • EINECS:
  • 200-135-7
  • Density:
  • 1.5 g/cm3
  • Melting Point:
  • 54-57 °C
  • Boiling Point:
  • 270.2 °C at 760 mmHg
  • Flash Point:
  • 117.2 °C
  • Solubility:
  • water: 19 g/100 mL (25 °C)
  • Appearance:
  • white crystals or powder
  • Hazard Symbols:
  • VeryT+
  • Risk Codes:
  • 45-46-28
  • Safety:
  • 53-22-26-36/37/39-45-36/37-28 Details
  • Transport Information:
  • UN 2811 6.1/PG 2
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CAS No.52-24-4 TriethylenethiophosphoramideCompetitive Product

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CAS No.52-24-4 Triethylenethiophosphoramide

Assay:≥99%(HPLC)  Appearance:Inqury  Package:1G,5G,119G

Supplier:Shanghai DEMO Medical Tech Co.,Ltd [ China (Mainland)]

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CAS No.52-24-4 Triethylenethiophosphoramide

Storage:2 to 8 ° C  Application:For breast a...

The molecular formula 】 C6H12N3PS The molecular weight 】 189.22 【 MOL file 】 52-24-4. Mol The chemical and physical properties back to the directory The melting point 】 54-57 ° C 【 form 】 solid 【 water solubility 】 19 G / 100 ML (25 o C)

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CAS No.52-24-4 Triethylenethiophosphoramide

EINECS:200-135-7 Molecular Formula: C6H12N3PS Molecular Weight: 189.2183 Density:1.5g/cm3 Melting point:54-57℃ Boiling point: 270.2°C at 760 mmHg Flash point:117.2°C Water solubility:19 g/100 mL (25℃)

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CAS No.52-24-4 Triethylenethiophosphoramide

200-135-7 C6H12N3PS 189.2183 InChI=1/C6H12N3PS/c11-10(7-1-2-7,8-3-4-8)9-5-6-9/h1-6H2

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CAS No.52-24-4 Triethylenethiophosphoramide

Assay:98%

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CAS No.52-24-4 Triethylenethiophosphoramide

Aziridine,1,1',1''-phosphinothioylidynetris-

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CAS No.52-24-4 Triethylenethiophosphoramide

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CAS No.52-24-4 Triethylenethiophosphoramide

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CAS No.52-24-4 Triethylenethiophosphoramide

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CAS No.52-24-4 Triethylenethiophosphoramide

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CAS No.52-24-4 Triethylenethiophosphoramide

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CAS No.52-24-4 Triethylenethiophosphoramide

CBNumber: CB0458870 Chemical Name: Triethylenethiophosphoramide Molecular Formula: C6H12N3PS Formula Weight: 189.22 CAS No.: 52-24-4 MOL File: Mol file

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CAS No.52-24-4 Triethylenethiophosphoramide

Thiotepa(Thioplex) is an alkylating agent used to treat cancer.

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CAS No.52-24-4 Triethylenethiophosphoramide

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CAS No.52-24-4 Triethylenethiophosphoramide

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CAS No.52-24-4 Triethylenethiophosphoramide

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Reference

Microvascularization and permeability of histohematic barriers of Guerin's carcinoma during its growth and after administration of thiotepa
Microvascularization and permeability of histohematic barriers of Guerin's carcinoma during its growth and after administration of thiotepa. Khananaev, L. I.; Fitsich, S. A. (Med. Inst., Ivano-Frankovsk, USSR). Radiobiologiya, 18(1), 110-14 (Russian) 1978. CODEN: RADOA8. ISSN: 0033-8192. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) Section cross-reference(s): 14 Radiotracer studies and injection of Paris blue into blood vessels of Guerin carcinoma transplanted into rats showed that the permeability of the tumor blood vessels decreased with its growth and is one of the factors restricting the antitumor effectiveness of thiotepa (I) [52-24-4].
Morphologic effects of thio-TEPA on mouse urothelium
Morphologic effects of thio-TEPA on mouse urothelium. Murphy, William M.; Soloway, Mark S.; Lin, Chiou Jin (Dep. Pathol., Univ. Tennessee Cent. Health Sci., Memphis, Tenn., USA). Acta Cytol., 21(5), 701-4 (English) 1977. CODEN: ACYTAN. ISSN: 0001-5547. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacodynamics) The urothelial changes induced by intravesical instillation of thio-TEPA [52-24-4] into exptl. animals were studied by cytologic, light microscopic, and electron microscopic techniques. Cells and tissue from treated and untreated groups were compared using a total of 54 discriminators. There were few consistent differences. Cells with marked nuclear atypia were not identified. Thus, thio-TEPA has little effect on nondiseased bladders. The atypical cells occasionally present in specimens from thio-TEPA-treated bladders apparently did not emanate from normal urothelium.
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