Products Categories
| CAS No.: | 5232-99-5 |
|---|---|
| Name: | Etocrilene |
| Article Data: | 17 |
| Molecular Structure: | |
|
|
|
| Formula: | C18H15NO2 |
| Molecular Weight: | 277.323 |
| Synonyms: | Acrylicacid, 2-cyano-3,3-diphenyl-, ethyl ester (6CI,7CI,8CI);2-Cyano-3,3-diphenyl-2-propenoic acid ethyl ester;2-Cyano-3-phenylcinnamicacid ethyl ester;CE 2;CE 2 (ultraviolet absorber);Ethyl2-cyano-3,3-diphenyl-2-propenoate;Ethyl 2-cyano-3,3-diphenylacrylate;Ethyl2-cyano-3,3-diphenylpropenoate;Ethyl a-cyano-b,b-diphenylacrylate;Ethyl a-cyano-b-phenylcinnamate;Etocrylene;NSC 52678;Seesorb 501;UV Absorber 2;Uvinul 3035;Uvinul N 35;Viosorb 910; |
| EINECS: | 226-029-0 |
| Density: | 1.141 g/cm3 |
| Melting Point: | 97-99 ºC |
| Boiling Point: | 407.6 ºC at 760 mmHg |
| Flash Point: | 199.4 ºC |
| Hazard Symbols: |
 Xi； N
|
| Risk Codes: | 36/37/38-50/53 |
| Safety: | 26-36-60-61 |
| Transport Information: | UN 3077 9/PG 3 |
| PSA: | 50.09000 |
| LogP: | 3.57518 |
- 81281-59-67-Benzylideneaminotheophylline
- 82993-81-5D-threo-Ritalinic acid hydrochloride
- 73441-42-6METHYL-5-CHLORO-2,2-DIMETHYLVALERATE
- 68439-39-4Poly(oxy-1,2-ethanediyl), alpha-(2-ethylhexyl)-omega-hydroxy-,
- 852475-26-4MC1568
- 958254-66-51H-Imidazo[4,5-b]pyridine-2-carboxaldehyde, 1-methyl-, hydrochloride
- 99170-93-1N-Methyl-2-oxazolamine
- 717878-06-31-(4-fluorophenyl)-4-nitro-1H-imidazole
- 914458-26-7[5-(2-fluorophenyl)-1-pentyl-1H-pyrrol-3-yl]-1-naphthalenyl-Methanone
- 548773-13-32-amino-4,6-dimethylpyrimidine-5-carboxylic acid
| Conditions | Yield |
|---|---|
| In methanol at 35 - 85℃; Inert atmosphere; | 96% |
| Conditions | Yield |
|---|---|
| With ammonium acetate; pyrographite In n-heptane for 15h; Ionic liquid; Reflux; | 94.1% |
| With acetic acid; 3-amino propanoic acid In benzene for 90h; Knoevenagel condensation; Heating; | 64% |
- 119-61-9
benzophenone
- 631-61-8
ammonium acetate
- 64-19-7
acetic acid
- 105-56-6
ethyl 2-cyanoacetate
- 71-43-2
benzene
- 5232-99-5
etocrylene
| Conditions | Yield |
|---|---|
| for 6h; Photolysis; |
| Conditions | Yield |
|---|---|
| In sodium carbonate | 99.8% |
| With sodium methylate In toluene for 8h; Reflux; | 144.3 g |
- 4437-01-8
3,6,9,12,15,18,21-heptaoxadocosan-1-ol
- 5232-99-5
etocrylene
- 1250862-76-0
2-cyano-3,3-diphenyl-acrylic acid [pluriol A350E] ester
| Conditions | Yield |
|---|---|
| Stage #1: 3,6,9,12,15,18,21-heptaoxadocosan-1-ol; etocrylene; titanium(IV) isopropylate at 155℃; for 24h; Inert atmosphere; Stage #2: With phosphoric acid In dichloromethane; water at 20℃; for 24h; | 95% |
| Stage #1: 3,6,9,12,15,18,21-heptaoxadocosan-1-ol at 150℃; for 0.5h; Inert atmosphere; Stage #2: etocrylene With titanium(IV) isopropylate at 155℃; for 24h; Stage #3: With phosphoric acid In dichloromethane at 20℃; for 24h; | 95% |
- 4437-01-8
3,6,9,12,15,18,21-heptaoxadocosan-1-ol
- 5232-99-5
etocrylene
A
- 64-17-5
ethanol
B
- 1250862-76-0
2-cyano-3,3-diphenyl-acrylic acid [pluriol A350E] ester
| Conditions | Yield |
|---|---|
| Stage #1: 3,6,9,12,15,18,21-heptaoxadocosan-1-ol; etocrylene With titanium(IV)isopropoxide at 150 - 155℃; for 25h; Inert atmosphere; Stage #2: With phosphoric acid In water at 20℃; for 24h; | A n/a B 95% |
- 5232-99-5
etocrylene
- 25634-96-2
ethyl α-cyano-ββ-diphenylpropionate
| Conditions | Yield |
|---|---|
| With copper(II) acetate monohydrate; tert-butyl alcohol In tetrahydrofuran at 20℃; for 1h; Inert atmosphere; Sealed tube; chemoselective reaction; | 94% |
| With methanol; (4,4'-di-tert-butyl-2,2'-dipyridyl)-bis-(2-phenylpyridine(-1H))-iridium(III) hexafluorophosphate; diethyl 2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate at 20℃; for 16h; Inert atmosphere; Irradiation; Sealed tube; | 93% |
| With lithium diisopropyl amide In tetrahydrofuran at 0℃; | 85% |
- 5232-99-5
etocrylene
- 10380-41-3
2-cyano-3,3-diphenylacrylic acid
| Conditions | Yield |
|---|---|
| Stage #1: etocrylene With water; sodium hydroxide In methanol at 20℃; Stage #2: With hydrogenchloride In methanol; water | 92% |
| Hydrolysis; | |
| Stage #1: etocrylene With sodium hydroxide In ethanol; water at 20℃; for 8h; Stage #2: With hydrogenchloride In ethanol; water | 3.2 g |
- 5232-99-5
etocrylene
| Conditions | Yield |
|---|---|
| With samarium diiodide In tetrahydrofuran at 65℃; for 2h; | 81% |
| With samarium; iodine In tetrahydrofuran at 65℃; for 10h; | 52% |
- 523-44-4ORANGE I
- 52357-70-7Iron oxide brown
- 52365-46-5Karl Fischer Reagent
- 52404-33-82-Propenoic acid, 2-hydroxyethyl ester, polymer with 1,1-methylenebis(4-isocyanatocyclohexane) and 2-oxepanone
- 52411-34-42-[2-(2-Aminophenoxy)ethoxy]phenylamine
- 52413-82-82-Chloro-4-(trichloromethyl)pyridine
- 524-38-9N-Hydroxyphthalimide
- 5244-34-83,6-Dithia-1,8-octanediol
- 104987-11-3Tacrolimus
- 141-53-7Sodium formate
- 8001-54-5Quaternary ammonium compounds, alkylbenzyldimethyl, chlorides
- 9003-39-8Povidone
- 10161-34-9Trenbolone acetate
- 402957-28-2Telaprevir
- 68-19-9Cyanocobalamin
What can I do for you?
Get Best Price
Consensus Reports
Specification
The 3,3-Dicyclopropyl-2-(ethoxycarbonyl)-acrylonitrile, with its CAS registry number 5232-99-5, has the IUPAC name of ethyl 2-cyano-3,3-diphenylprop-2-enoate. As used as a pharmaceutical intermediate, its product categories are including C12 to C63 Polymer Science; Carbonyl Compounds; Esters; Polymer Additives; Stabilizers.
The physical properties of this chemical are as below: (1)ACD/LogP: 4.52; (2)# of Rule of 5 Violations: 0; (3)#H bond acceptors: 3; (4)#H bond donors: 0; (5)#Freely Rotating Bonds: 5; (6)Polar Surface Area: 50.09; (7)Index of Refraction: 1.577; (8)Molar Refractivity: 80.61 cm3; (9)Molar Volume: 243 cm3; (10)Polarizability: 31.95×10-24 cm3; (11)Surface Tension: 46.1 dyne/cm; (12)Density: 1.141 g/cm3; (13)Flash Point: 199.4 °C; (14)Enthalpy of Vaporization: 65.95 kJ/mol; (15)Boiling Point: 407.6 °C at 760 mmHg; (16)Vapour Pressure: 7.46E-07 mmHg at 25°C; (17)Exact Mass: 277.110279; (18)MonoIsotopic Mass: 277.110279; (19)Topological Polar Surface Area: 50.1; (20)Heavy Atom Count: 21; (21)Complexity: 411.
Use of this chemical: 3,3-Dicyclopropyl-2-(ethoxycarbonyl)-acrylonitrile could react to produce 2-cyano-3,3-diphenyl-propionic acid ethyl ester. This reaction could happen in the presence of the reagent of palladium/charcoal and acetone in the condition of Hydrogenation.
.jpg)
When you are dealing with this chemical, you should be very careful. For one thing, it is irritating to eyes, respiratory system and skin and then may cause inflammation to the skin or other mucous membranes. For another thing, it is dangerous for the environment which may present an immediate or delayed danger to one or more components of the environment. For being very toxic to aquatic organisms, it may cause long-term adverse effects in the aquatic environment.
Therefore, you should wear suitable protective clothing. If in case of contact with eyes, rinse immediately with plenty of water and seek medical advice. When store it, this material and its container must be disposed of as hazardous waste and remember to avoid releasing to the environment. You could also refer to special instructions/safety data sheet.
In addition, you could convert the following datas into the molecular structure:
(1)Canonical SMILES: CCOC(=O)C(=C(C1=CC=CC=C1)C2=CC=CC=C2)C#N
(2)InChI: InChI=1S/C18H15NO2/c1-2-21-18(20)16(13-19)17(14-9-5-3-6-10-14)15-11-7-4-8-12-15/h3-12H,2H2,1H3
(3)InChIKey: IAJNXBNRYMEYAZ-UHFFFAOYSA-N
Below are the toxicity information of this chemical:
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| mouse | LD50 | intraperitoneal | 100mg/kg (100mg/kg) | National Technical Information Service. Vol. AD277-689, |