Detail of > 557-61-9
- MSDS Download

- CAS Number:
- 557-61-9
- Name:
1-Octacosanol
- Formula:
- C28H58O
- Molecular Structure:

- Synonyms:
- montanyl alcohol;octacosyl alcohol;octacosan-1-ol;Cluytyl alcohol;Octacosanol;n-octacosanol;Octacosanol (Policosanol);Policosanol (Octacosanol);
- Molecular Weight:
- 410.76
- EINECS:
- 209-181-2
- Density:
- 0.841 g/cm3
- Melting Point:
- 81-83 °C
- Boiling Point:
- 428.1 °C at 760 mmHg
- Flash Point:
- 135.3 °C
- Solubility:
- <0.1 g/100 mL at 21.5 °C in water
- Appearance:
- white crystals or powder
- Hazard Symbols:
Xn- Risk Codes:
- 20/21/22-36/37/38
- Safety:
- 22-24/25-37/39-26Details
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Reference
- Wheat germ oil and its application to health food
- Wheat germ oil and its application to health food. Nagai, Masanobu (Nisshin Seibun Co., Ltd., Japan). Jpn. Fudo Saiensu, 23(1), 39-48 (Japanese) 1984. CODEN: JAFSAA. ISSN: 0368-1122. DOCUMENT TYPE: Journal; General Review CA Section: 17 (Food and Feed Chemistry) A review with 9 refs., discussing wheat germ oil as a source of vitamin E analogs, the history, characteristics, and occurrence of vitamin E analogs, prodn. of wheat germ oil, physiol. activities of vitamin E analogs, linoleic acid [60-33-3], and octacosanol [557-61-9], and use of wheat germ oil as a health food.
- Eulipidemic effects of berberine administered alone or in combination with other natural cholesterol-lowering agents: a single-blind clinical investigation
- All Rights Reserved. Eulipidemic effects of berberine administered alone or in combination with other natural cholesterol-lowering agents: a single-blind clinical investigation. Cicero, Arrigo F. G.; Rovati, Lucio C.; Setnikar, Ivo ("G. Descovich" Atherosclerosis and Dysmetabolic Disease Research Center, "D. Campanacci" Clinical Medicine and Applied Biotechnology Department, University of Bologna, Bologna, Italy). Arzneimittel Forschung, 57(1), 26-30 (English) 2007 Editio Cantor Verlag. CODEN: ARZNAD. ISSN: 0004-4172. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) Section cross-reference(s): 18 Berberine (BERB) and a combination (COMB) of berberine (CAS 2086-83-1) with policosanol (CAS 557-61-9), red yeast ext. (contg. monacolin, CAS 557-61-9), folic acid, and astaxanthin were orally administered daily for 4 wk to 40 subjects with moderate dyslipidemias divided in 2 parallel groups each of 20 subjects. Total cholesterol (TC), LDL, HDL, Non HDL, ApoB, ApoA, Lp(a), and triglycerides (TG) were measured before and at the end of treatments. BERB and COMB significantly reduced TC (resp. by 16 and 20%), LDL (by 20 and 25%), ApoB (by 15 and 29%), and TG (by 22 and 26%), and increased HDL (by 6.6 and 5.1%). Adverse events or impairments of liver transaminases or of CPK were not obsd. In conclusion, food supplements contg. natural products such as berberine, policosanol, red yeast exts., folic acid, and astaxanthin could be a useful support to diet and life style changes to correct dyslipidemias and to reduce cardiovascular risk in subjects with moderate mixed dyslipidemias.
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