Detail of "69-53-4"

CAS Number:
69-53-4
Name:
4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-
Superlist Name:
Ampicillin
Molecular Structure:
Formula:
C₁₆H₁₉N₃O₄S
Molecular Weight:
349.40 .
Deleted CAS:
98520-55-9|8056-87-9|50584-05-9|47355-94-2|37234-64-3|33604-21-6
Synonyms:
Guicitrina;Marisilan;Nuvapen;Omnipe;Penbristol;Penbritin;Penbritin paediatric;Penbritinsyrup;Penicillin, (aminophenylmethyl)-;Penicline;Pentrexyl;Polyflex;Ponecil;Principen;Roscillin;Synpenin;Tokiocillin;Tolomol;Totacillin;Totalciclina;Ultrabion;Ultrabron;Viccillin;Viccillin S;Wy 5103;4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-(2-amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-, D-(-)- (8CI);4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, 6-[(aminophenylacetyl)amino]-3,3-dimethyl-7-oxo-,[2S-[2a,5a,6b(S*)]]-;(-)-6-(2-Amino-2-phenylacetamido)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid;A-Pen;Adobacillin;Albipen;Alpen;Amblosin;Amfipen;Amipenix;Amipenix S;Amotital;Ampi-Bol;Ampi-kel;Ampicillin;Ampicillin A;Ampimed;Ampisyn;Ampitab;Ampivet;Amplital;Austrapen;BRL 1341;Binotal;Britacil;Campicillin;Copharcilin;D-(-)-6-(a-Aminophenylacetamido)penicillanicacid;D-(-)-Ampicillin;D-(-)-a-Aminobenzylpenicillin;D-(-)-a-Aminopenicillin;Dumopen;Ficillin;Grampenil;
EINECS:
200-709-7
Density:
1.45 g/cm³
Melting Point:
198-200 °C (dec.)(lit.)
Boiling Point:
683.9 °C at 760 mmHg
Flash Point:
367.4 °C
Solubility:
NH4OH 1 M: 50 mg/mL, clear, colorless
Appearance:
Crystalline solid
Hazard Symbols:
Xn
Risk Codes:
36/37/38-42/43
Safety:
22-26-36/37 Details

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CAS No.69-53-4 Ampicillin

Package:23.7USD/KG

Supplier:SHINING HEALTH GROUP LIMITED [ China (Mainland)]

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CAS No.69-53-4 Ampicillin

Assay:96.0%~102.0% Appearance:White crysta... Package:25 kgs/ durmStorage:Cool, dry, d... Transportation:deliver with... Application:Health and m...

Molecular Formula: C16H19N3O4S Standard :USP25 BP2000 Function: used for the manufacture of film-coated tablets, capsules, granules for oral suspensions and sachets.

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Appearance:White or Alm...

Molecular Formula:C16H19N3O4S Molecular Weight:349.40 . EINECS:200-709-7 Melting Point:208 C Boiling Point: Vapour density: Solubility: Risk Codes:R36/37/38;R42/43 Details

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AMPICILLIN

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CAS No.69-53-4 Ampicillin

AMPICILLIN TRIHYDRATE

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Reference

Pharmacokinetic studies of ampicillin during and following intravenous drip infusion in human healthy volunteers: Pharmacokinetic studies of ampicillin during and following intravenous drip infusion in human healthy volunteers. Imoto, Takashi (Sch. Med., Tokai Univ., Isehara 259-11, Japan). Jpn. J. Antibiot., 37(4), 663-70 (Japanese) 1984. CODEN: JJANAX. ISSN: 0368-2781. DOCUMENT TYPE: Journal CA Section: 1 (Pharmacology) In healthy subjects, the blood serum level of 1.56 mg ampicillin [69-53-4]/mL was attained by infusion of i.v. 0.5 ~ 2.0g ampicillin/1 ~ 5 h, but the level of 6.25 mg/mL was attained effectively by infusing 0.5 g/1-3 h. A level of 25 mg ampicillin/mL was seen after 1 g drug infusion in < 1 h or 2 g in < 4 h.

Enhancement of rectal absorption of ampicillin by sodium salicylate in rabbits: Enhancement of rectal absorption of ampicillin by sodium salicylate in rabbits. Nishihata, Toshiaki; Sakakura, Tomoko; Hitomi, Mire; Yamazaki, Masaru; Kamada, Akira (Fac. Pharm. Sci., Osaka Univ., Suita 565, Japan). Chem. Pharm. Bull., 32(6), 2433-8 (English) 1984. CODEN: CPBTAL. ISSN: 0009-2363. DOCUMENT TYPE: Journal CA Section: 63 (Pharmaceuticals) Section cross-reference(s): 1 The enhancing action of Na salicylate [54-21-7] on rectal ampicillin (I) [69-53-4] absorption in rabbits showed a strong dependency on the concn. of Na salicylate in the administered soln. Max. bioavailability of I obtained when increasing Na salicylate concn. was 60-70%. Although max. bioavailability of I administered as a suppository was also 60-70%, the suppository formulation required a significantly lower dose of Na salicylate compared to the soln., suggesting that the effective fluid vol. available to dissolve drugs in rabbits might be very small. Further, Na ion might enhance the adjuvant action of Na salicylate.

Detail of "69-53-4"

4-Thia-1-azabicyclo[3.2.0]heptane-2-carboxylicacid, 6-[[(2R)-2-amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-, (2S,5R,6R)-

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Reference