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CAS No.: | 75-03-6 |
---|---|
Name: | Ethyl iodide |
Article Data: | 308 |
Molecular Structure: | |
Formula: | C2H5I |
Molecular Weight: | 155.966 |
Synonyms: | AI3-28593;Ethyl iodide;Ethyljodid;Hydriodic ether;Jodethan;Monoiodoethane;NSC 8825; |
EINECS: | 200-833-1 |
Density: | 1.94 g/cm3 |
Melting Point: | -108 °C |
Boiling Point: | 72.8 °C at 760 mmHg |
Flash Point: | 21.1 °C |
Solubility: | 4 g/L in water at 20 °C |
Appearance: | Colorless to yellow liquid |
Hazard Symbols: | Xn,T |
Risk Codes: | 20-36/37/38-42/43-10-23/24/25 |
Safety: | 23-26-45-16-36/37/39-27 |
PSA: | 0.00000 |
LogP: | 1.44130 |
Conditions | Yield |
---|---|
In tetrachloromethane Kinetics; Irradiation (UV/VIS); Kinetics of the reaction of Co(C2H5)(H3CCNOHONCCH3)2(C5H5N) with I2 under irradiation with light at 517 nm is investigated.; MeI and CoI(H3CCNOHONCCH3)2(C5H5N) are the products.; | A n/a B 100% |
ethyl iodide
Conditions | Yield |
---|---|
With iodine In acetonitrile Kinetics; byproducts: {Co(bis(dimethylglyoximato))py(I)}; one-electron oxidn. of Co complex by I2 at 298 K; monitored by (1)H-NMR and UV spect. (361 nm); | 100% |
Conditions | Yield |
---|---|
at 90 - 170℃; for 0.166667h; Arbuzov Reaction; | A n/a B 98% C n/a |
triethyl phosphite
methyl iodide
A
Diethyl methylphosphonate
B
ethyl iodide
Conditions | Yield |
---|---|
at 130℃; for 0.0833333h; Michaelis-Arbuzov reaction; microwave irradiation; | A 97% B n/a |
Conditions | Yield |
---|---|
With iodine In acetonitrile Kinetics; byproducts: I3(1-), {(C2H5)Co(2,2'-bipyridine)2I}(1+); one-electron oxidn. of cis-Co complex by I2 at 298 K; monitored by (1)H-NMR and UV spect. (361 nm); | A <1 B <1 C 97% D 3.2% |
methoxyethene
propargyl alcohol
A
3-(1-methoxy-ethoxy)-propyne
B
ethyl iodide
Conditions | Yield |
---|---|
With toluene-4-sulfonic acid | A 96% B n/a |
iodobenzene
triethyl phosphite
A
diethyl phenylphosphonate
B
ethyl iodide
Conditions | Yield |
---|---|
tetrakis(triethylphosphite)nickel(0) at 160℃; | A 94% B n/a |
at 160℃; Mechanism; var. catalysts, var. temp.; |
Conditions | Yield |
---|---|
In diethyl ether for 2h; Ambient temperature; | A n/a B 92% |
trimethylsilyl iodide
ethyl acetate
A
trimethylsilyl acetate
B
ethyl iodide
Conditions | Yield |
---|---|
at 100℃; for 0.5h; Mechanism; Product distribution; | A n/a B 92% |
4-vinylbenzyl iodide
triethyl phosphite
A
[(4-ethenylphenyl)methyl]phosphonic acid diethyl ester
B
ethyl iodide
Conditions | Yield |
---|---|
at 20℃; for 6h; | A 91% B n/a |
Reported in EPA TSCA Inventory.
The Ethane, iodo-, with the CAS registry number 75-03-6, is also known as Monoiodoethane. Its EINECS number is 200-833-1. This chemical's molecular formula is C2H5I and molecular weight is 155.97. What's more, its systematic name is iodoethane. Its classification code is Mutation data. Ethyl iodide is very good with alkylation reactions. It is used as organic reagents and pharmaceutical intermediates. It is also used as the hydrogen radical promoter. It should be sealed and stored in a cool, ventilated and dry place. Moreover, it should be protected from light, heat and fire.
Physical properties of Ethane, iodo- are: (1)ACD/LogP: 2.03; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 2.03; (4)ACD/LogD (pH 7.4): 2.03; (5)ACD/BCF (pH 5.5): 20.48; (6)ACD/BCF (pH 7.4): 20.48; (7)ACD/KOC (pH 5.5): 302.23; (8)ACD/KOC (pH 7.4): 302.23; (9)Index of Refraction: 1.516; (10)Molar Refractivity: 24.28 cm3; (11)Molar Volume: 80.3 cm3; (12)Polarizability: 9.62×10-24cm3; (13)Surface Tension: 28.5 dyne/cm; (14)Density: 1.94 g/cm3; (15)Flash Point: 21.1 °C; (16)Enthalpy of Vaporization: 29.44 kJ/mol; (17)Boiling Point: 72.8 °C at 760 mmHg; (18)Vapour Pressure: 128 mmHg at 25°C.
Preparation: this chemical can be prepared by ethanol and PI3 by heating and reflux.
2P + 3I2 → 2PI3
3C2H5OH + PI3 →3CH3CH2I + H3PO4
Uses of Ethane, iodo-: it can be used to produce 1-ethyl-3-nitro-2-phenyl-indole by heating. It will need reagent Na and solvent ethanol with the reaction time of 2 hours. The yield is about 59%.
When you are using this chemical, please be cautious about it as the following:
This chemical is flammable, so you should keep it away from sources of ignition - No smoking. It is harmful by inhalation. It is toxic by inhalation, in contact with skin and if swallowed. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. You must not breathe gas/fumes/vapour/spray (appropriate wording to be specified by the manufacturer). You should take off immediately all contaminated clothing. When using it, you need wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, you must seek medical advice immediately (show the label where possible).
You can still convert the following datas into molecular structure:
(1)InChI: InChI=1S/C2H5I/c1-2-3/h2H2,1H3
(2)InChIKey: HVTICUPFWKNHNG-UHFFFAOYSA-N
(3)Canonical SMILES: CCI
The toxicity data is as follows:
Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
---|---|---|---|---|---|
guinea pig | LD50 | intraperitoneal | 322mg/kg (322mg/kg) | "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 68, 1982. | |
mouse | LD50 | intraperitoneal | 560mg/kg (560mg/kg) | "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 68, 1982. | |
mouse | LD50 | subcutaneous | 1gm/kg (1000mg/kg) | PERIPHERAL NERVE AND SENSATION: FLACCID PARALYSIS WITHOUT ANESTHESIA (USUALLY NEUROMUSCULAR BLOCKAGE) LUNGS, THORAX, OR RESPIRATION: RESPIRATORY STIMULATION LUNGS, THORAX, OR RESPIRATION: OTHER CHANGES | Japanese Journal of Pharmacology. Vol. 3, Pg. 99, 1954. |
rabbit | LDLo | oral | 300mg/kg (300mg/kg) | "Patty's Industrial Hygiene and Toxicology," 3rd rev. ed., Clayton, G.D., and F.E. Clayton, eds., New York, John Wiley & Sons, Inc., 1978-82. Vol. 3 originally pub. in 1979; pub. as 2n rev. ed. in 1985.Vol. 2B, Pg. 3487, 1981. | |
rat | LC50 | inhalation | 65gm/m3/30M (65000mg/m3) | Fiziologicheski Aktivnye Veshchestva. Physiologically Active Substances. Vol. 7, Pg. 35, 1975. | |
rat | LD50 | intraperitoneal | 330mg/kg (330mg/kg) | "Toxicometric Parameters of Industrial Toxic Chemicals Under Single Exposure," Izmerov, N.F., et al., Moscow, Centre of International Projects, GKNT, 1982Vol. -, Pg. 68, 1982. |