Reference

Determination of the configuration of a compound containing labile protons in water solution with NMR techniques

All Rights Reserved. Determination of the configuration of a compound containing labile protons in water solution with NMR techniques. Feng, Jinping; Pan, Yanna; Ou, Yangjie; Li, Weichao; Deng, Zhiwei ( Analytical + Testing Center, Beijing Normal University, Beijing 100875, Peop. Rep. China). Fenxi Ceshi Xuebao, 24(6), 1-5 (Chinese) 2005 Fenxi Ceshi Xuebao Bianjibu. CODEN: FCEXES. ISSN: 1004-4957. DOCUMENT TYPE: Journal CA Section: 80 (Organic Analytical Chemistry) The configuration of a water-sol. compd. contg. labile protons in water soln. was analyzed by NMR technique.Several substances like 75498-96-3 may be metioned in this study. The sample was directly dissolved in deionized water, and an external std. of D2O was used for deuterium lock. The NMR expt. can then be performed in a normal way, and the exchange between the deuterium and labile protons can be avoided. The expts. provided direct information for the orientation of the labile protons in the compd. To assure the quality of the NMR graph obtained by the external std. for deuterium lock, several other techniques including solvent peak suppression, were used for the NMR tests. A group of 1-dimensional and 2-dimensional spectra with high quality were obtained. Based on the method, the configuration of cefminox Na was detd. satisfactorily. .