Detail of > 82248-59-7
- CAS Number:
- 82248-59-7
- Name:
Benzenepropanamine,N-methyl-g-(2-methylphenoxy)-,hydrochloride (1:1), (gR)-
- Superlist Name:
- Atomoxetine hydrochloride
- Formula:
- C17H22ClNO
- Molecular Structure:

- Synonyms:
- Benzenepropanamine,N-methyl-g-(2-methylphenoxy)-,hydrochloride, (R)-;Benzenepropanamine, N-methyl-g-(2-methylphenoxy)-, hydrochloride, (gR)- (9CI);(R)-(-)-N-Methyl-3-[(2-methylphenyl)oxy]-3-phenyl-1-aminopropane hydrochloride;(R)-(-)-Tomoxetine hydrochloride;(R)-N-Methyl-3-(2-methylphenoxy)-3-phenylpropylamine hydrochloride;(R)-Tomoxetine hydrochloride;Atomoxetine hydrochloride;LY 139603;Strattera;Tomoxetine hydrochloride;(3R)-N-Methyl-3-(2-methylphenoxy)-3-phenyl-1-propanamine hydrochloride (1:1);(3R)-N-méthyl-3-(2-méthylphénoxy)-3-phénylpropan-1-amine chlorhydrate;benzenepropanamine, N-methyl-γ-(2-methylphenoxy)-, (gammaR)-, hydrochloride;Atomoxetine HCL;
- Molecular Weight:
- 291.82
- Boiling Point:
- 389 °C at 760 mmHg
- Flash Point:
- 164.1 °C
- Appearance:
- solid
- Safety:
- 22-24/25Details
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Reference
- Treatment of allergic rhinitis and asthma with atomoxetine
- Treatment of allergic rhinitis and asthma with atomoxetine. Dunaway, Leslie Joe (USA ). PCT Int. Appl. WO 2005011583 A2 10 Feb 2005,9 pp. DESIGNATED STATES: W: AE, AG, AL, AM, AT, AU, AZ, BA, BB, BG, BR, BW, BY, BZ, CA, CH, CN, CO, CR, CU, CZ, DE, DK, DM, DZ, EC, EE, EG, ES, FI, GB, GD, GE, GH, GM, HR, HU, ID, IL, IN, IS, JP, KE, KG, KP, KR, KZ, LC, LK, LR, LS, LT, LU, LV, MA, MD, MG, MK, MN, MW, MX, MZ, NA, NI, NO, NZ, OM, PG, PH, PL, PT, RO, RU, SC, SD, SE, SG, SK, SL, SY, TJ, TM, TN, TR, TT, TZ, UA, UG, US, UZ, VC, VN, YU, ZA, ZM, ZW; RW: AT, BE, BF, BJ, CF, CG, CH, CI, CM, CY, DE, DK, ES, FI, FR, GA, GB, GR, IE, IT, LU, MC, ML, MR, NE, NL, PT, SE, SN, TD, TG, TR. (English).In this article, certain chemicals are used. Some of their cas registry numbers are 83015-26-3 and 82248-59-7 (World Intellectual Property Organization). CODEN: PIXXD2. CLASS: ICM: A61K. APPLICATION: WO 2004-US24125 27 Jul 2004. PRIORITY: US 2003-PV490644 28 Jul 2003. DOCUMENT TYPE: Patent CA Section: 1 (Pharmacology) This invention provides a method of treating allergic rhinitis in a mammal comprising administering a therapeutically effective amt. of atomoxetine to a mammal in need of such treatment, and also provides a method of treating asthma in a mammal comprising administering a therapeutically effective amt. of atomoxetine to a mammal in need of such treatment. .
- Atomoxetine treatment of attention-deficit/hyperactivity disorder
- Atomoxetine treatment of attention-deficit/hyperactivity disorder. Eiland, Lea S.; Guest, Abby L. (Harrison School of Pharmacy, Auburn Univ., Huntsville, AL, USA). Annals of Pharmacotherapy, 38(1), 86-90 (English) 2004 Harvey Whitney Books Co. CODEN: APHRER.Some commonly used reagents like 82248-59-7 and 51-41-2 are used in this experiment. ISSN: 1060-0280. DOCUMENT TYPE: Journal; General Review CA Section: 1 (Pharmacology) A review. Objective: To review the literature of the first nonstimulant approved for treatment of attention-deficit/hyperactivity disorder (ADHD). Data Sources: Primary literature and review articles were obtained through PubMed/MEDLINE (1966-Feb. 2003). Study Selection and Data Extn.: Literature evaluating atomoxetine in ADHD was selected. Animal data were excluded. Data Synthesis: Stimulants are currently first-line therapy for ADHD. However, their use raises several concerns including the potential for abuse and adverse effects. Atomoxetine introduces a new therapeutic drug class, selective norepinephrine-reuptake inhibitors, for ADHD management. This addnl. treatment option offers potential advantages over current therapies. Conclusions: Clin. trials demonstrate that atomoxetine is a safe and effective alternative for ADHD treatment in children and adults; however, its disadvantages may hinder it from becoming a first-line agent. .
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