1120-24-7Relevant articles and documents
Overriding Intrinsic Reactivity in Aliphatic C?H Oxidation: Preferential C3/C4 Oxidation of Aliphatic Ammonium Substrates
Heilmann, Michael,Knezevic, Melina,Piccini, Giovanni Maria,Tiefenbacher, Konrad
, p. 12387 - 12391 (2020)
The site-selective C?H oxidation of unactivated positions in aliphatic ammonium chains poses a tremendous synthetic challenge, for which a solution has not yet been found. Here, we report the preferential oxidation of the strongly deactivated C3/C4 positions of aliphatic ammonium substrates by employing a novel supramolecular catalyst. This chimeric catalyst was synthesized by linking the well-explored catalytic moiety Fe(pdp) to an alkyl ammonium binding molecular tweezer. The results highlight the vast potential of overriding the intrinsic reactivity in chemical reactions by guiding catalysis using supramolecular host structures that enable a precise orientation of the substrates.
Method for synthesizing N, N-dimethyl decylamine by using tetrapolypropylene and hydrocyanic acid
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Paragraph 0018-0026, (2021/04/07)
The invention discloses a method for synthesizing N, N-dimethyl decylamine by using tetrapolypropylene and hydrocyanic acid, and relates to the technical field of comprehensive development, extension and utilization of petrochemical products, which comprises the following steps: by using tetrapolypropylene and acrylonitrile byproduct hydrocyanic acid as initial raw materials, adding tetrapolypropylene and a solvent into a reaction kettle; and dropwise adding hydrocyanic acid and a catalyst in a cooling and stirring state, carrying out a heat preservation reaction after dropwise adding is finished, then adding methanol and pure water after the heat preservation reaction is finished, carrying out a stirring reaction, and carrying out neutralization, standing phase splitting, distillation purification and the like after the stirring reaction is finished to prepare N, N-dimethyl decylamine. The invention researches and develops a new synthesis process of N, N-dimethyl decylamine, develops a new high-added-value utilization way of the byproduct hydrocyanic acid of tetrapolypropylene and acrylonitrile, enables the industrial chain of the byproduct hydrocyanic acid of tetrapolypropylene and acrylonitrile which are propylene downstream products to extend to fine chemical products, and improves the economic benefits of the propylene downstream industrial chain products.
Dimethylamination of Primary Alcohols Using a Homogeneous Iridium Catalyst: A Synthetic Method for N, N-Dimethylamine Derivatives
Jeong, Jaeyoung,Fujita, Ken-Ichi
, p. 4053 - 4060 (2021/03/09)
A new catalytic system for N,N-dimethylamination of primary alcohols using aqueous dimethylamine in the absence of additional organic solvents has been developed. The reaction proceeds via borrowing hydrogen processes, which are atom-efficient and environmentally benign. An iridium catalyst bearing an N-heterocyclic carbene (NHC) ligand exhibited high performance, without showing any deactivation under aqueous conditions. In addition, valuable N,N-dimethylamine derivatives, including biologically active and pharmaceutical molecules, were synthesized. The practical application of this methodology was demonstrated by a gram-scale reaction.