150726-07-1

Basic information

• Product Name: p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxy-phenoxy)-2-methyl-4-pyrimidinyl]benzenesulfonamide
• CAS NO: 150726-07-1
• Molecular Weight: 487.577
• Mol File: 150726-07-1.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxy-phenoxy)-2-methyl-4-pyrimidinyl]benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxy-phenoxy)-2-methyl-4-pyrimidinyl]benzenesulfonamide(150726-07-1)
• EPA Substance Registry System: p-tert-butyl-N-[6-(2-hydroxyethoxy)-5-(o-methoxy-phenoxy)-2-methyl-4-pyrimidinyl]benzenesulfonamide(150726-07-1)

Safety Data

• Hazardous Substances Data: 150726-07-1(Hazardous Substances Data)

Upstream product

• 107-21-1 ethylene glycol 
• 150726-86-6 4-tert-butyl-N-[6-chloro-5-(o-methoxyphenoxy)-2-methyl-4-pyrimidinyl]-benzene sulfonamide 
• 6292-59-7 4-tert-butylbenzenesulphonamide 
• 20730-58-9 2-(2-Methoxyphenoxy)propanedioic acid diethyl ester 
• 150726-83-3 4,6-dichloro-5-(o-methoxyphenoxy)-2-methyl-pyrimidine 
• 329924-93-8 5-(o-methoxyphenoxy)-4,6-dihydroxy-2-methyl-pyrimidine 

Downstream Products

• 167402-17-7 pyridin-2-ylcarbamic acid 2-[6-(4-tert-butyl-phenylsulfonylamino)-5-(2-methoxy-phenoxy)-2-methyl-pyrimidin-4-yloxy]-ethyl ester 

Relevant articles and documents

Modifications and structure-activity relationships at the 2-position of 4-sulfonamidopyrimidine derivatives as potent endothelin antagonists

To improve water solubility and to study structure-activity relationships, we modified the structure of the pyrimidine nucleus of each of a series of potent ETA antagonists, 3a and 4a, at the 2-position. In a previous study, each of these antag

SULFONAMIDES

The novel sulfonamides of formula I, STR1 in which the symbols R. sup.1-R 9, R a, R b, X, Y and n have the significance given in the description and salts thereof can be used for the treatment of circulatory disorders, especially hypertension, ischemia, vasopasms and angina pectoris.