166814-83-1Relevant articles and documents
Novel peptidomimetic hematoregulatory compounds
Heerding, Dirk A.,Abruzzese, Melanie,Alberts, Doreen,Burgess, Joelle,Callahan, James F.,Huffman, William F.,King, Andrew G.,Locastro, Stephen,Demarsh, Peter,Pelus, Louis M.,Takata, Joanne S.,Bhatnagar, Pradip K.
, p. 531 - 534 (2007/10/03)
The activity of a novel series of peptidomimetic hematoregulatory compounds, designed based on a pharmacophore model inferred from the structure-activity relationships of a peptide SK and F 107647 (1), is reported. These compounds induce a hematopoietic synergistic factor (HSF) which in turn modulates host defense. The compounds may represent novel therapeutic agents in the area of hematoregulation. (C) 2000 Elsevier Science Ltd. All rights reserved.