2079-89-2 Usage
Chemical Properties
WHITE CRYSTALLINE POWDER
Uses
3-Aminopropionitrile fumarate salt has been used as a lysyl oxidase (LOX) inhibitor:to inhibit collagen cross-linking during microtissue formation and culturein LIM domain only 1 (LMO1)- or vector-expressing BE2C neuroblastoma cell line in transwell migration and invasion assayin lysyl oxidase (LOX) activity assayto study requirement of LOX activity for inducing hypoxia-inducible factor (HIF)2A-dependent stiffness in mouse organoids
Definition
ChEBI: A fumarate salt prepared from beta-aminopropionitrile by reaction of one molecule of fumaric acid for every two molecules of beta-aminopropionitrile.
Biochem/physiol Actions
3-Aminopropionitrile (β-Aminopropionitrile (BAPN)) functions as an irreversible inhibitor of lysyl oxidase (LOX), an enzyme involved in collagen cross-linking.
Safety Profile
Moderately toxic by ingestion and intraperitoneal routes. An experimental teratogen. When heated to decomposition it emits toxic fumes of NO, and CN-. See also NITRILES.
Check Digit Verification of cas no
The CAS Registry Mumber 2079-89-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,0,7 and 9 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 2079-89:
(6*2)+(5*0)+(4*7)+(3*9)+(2*8)+(1*9)=92
92 % 10 = 2
So 2079-89-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H4O4.2C3H6N2/c5-3(6)1-2-4(7)8;2*4-2-1-3-5/h1-2H,(H,5,6)(H,7,8);2*1-2,4H2/b2-1-;;