49656-91-9

Basic information

• Product Name: (4,5-DIPHENYL-4H-[1,2,4]TRIAZOL-3-YLSULFANYL)-ACETIC ACID HYDRAZIDE
• Synonyms: Aceticacid, 2-[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)thio]-, hydrazide
• CAS NO: 49656-91-9
• Molecular Formula: C₁₆H₁₅N₅OS
• Molecular Weight: 325.39
• Mol File: 49656-91-9.mol
• Article Data: 6

Chemical Properties

• Melting Point: 217-218 °C(Solv: ethanol (64-17-5))
• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Appearance: /
• Density: 1.36g/cm³
• Refractive Index: 1.702
• PKA: 11.70±0.37(Predicted)
• CAS DataBase Reference: (4,5-DIPHENYL-4H-[1,2,4]TRIAZOL-3-YLSULFANYL)-ACETIC ACID HYDRAZIDE(CAS DataBase Reference)
• NIST Chemistry Reference: (4,5-DIPHENYL-4H-[1,2,4]TRIAZOL-3-YLSULFANYL)-ACETIC ACID HYDRAZIDE(49656-91-9)
• EPA Substance Registry System: (4,5-DIPHENYL-4H-[1,2,4]TRIAZOL-3-YLSULFANYL)-ACETIC ACID HYDRAZIDE(49656-91-9)

Safety Data

• Hazardous Substances Data: 49656-91-9(Hazardous Substances Data)

Usage

General Description

(4,5-Diphenyl-4H-[1,2,4]triazol-3-ylsulfanyl)-acetic acid hydrazide is a chemical compound with potential applications in various fields including pharmaceuticals and agriculture. It is a hydrazide derivative of acetic acid and contains a triazole ring with a phenyl group attached to it. The compound has attracted interest due to its potential as a bioactive molecule with antimicrobial and antifungal properties. It also has the potential to act as a chelating agent or as a precursor in the synthesis of organic compounds. Its unique structure and properties make it a target for further research and potential applications in various industries.

InChI:InChI=1/C16H15N5OS/c17-18-14(22)11-23-16-20-19-15(12-7-3-1-4-8-12)21(16)13-9-5-2-6-10-13/h1-10H,11,17H2,(H,18,22)

Upstream product

• 13153-01-0 1-benzoyl-4-phenyl-3-thiosemicarbazide 
• 1768-59-8 1,4-diphenylthiosemicarbazide 
• 6596-82-3 4,5-diphenyl-2,4-dihydro-[1,2,4]triazole-3-thione 
• 6596-82-3 4,5-diphenyl-4H-1,2,4-triazole-3-thiol 
• 613-94-5 benzoic acid hydrazide 
• 103-72-0 phenyl isothiocyanate 
• 91759-70-5 ethyl 2-[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]acetate 

Downstream Products

• 93300-42-6 2-[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]-N-[(4-methylphenyl)methylidene]acetohydrazide 
• 93300-37-9 5-(4,5-Diphenyl-4H-[1,2,4]triazol-3-ylsulfanylmethyl)-4-naphthalen-1-yl-4H-[1,2,4]triazole-3-thiol 
• 1415559-07-7 4-ethyl-5-{[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-4H-1,2,4-triazole-3(2H)-thione 
• 58360-48-8 4-allyl-5-{[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-4H-1,2,4-triazole-3(2H)-thione 
• 537016-49-2 4-cyclohexyl-5-{[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-4H-1,2,4-triazole-3(2H)-thione 
• 58360-47-7 4-phenyl-5-{[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-4H-1,2,4-triazole-3(2H)-thione 
• 449782-42-7 4-(4-bromophenyl)-5-{[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-4H-1,2,4-triazole-3(2H)-thione 
• 1400271-85-3 4-(4-chlorophenyl)-5-{[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-4H-1,2,4-triazole-3(2H)-thione 
• 537016-53-8 4-(4-methoxyphenyl)-5-{[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-4H-1,2,4-triazole-3(2H)-thione 
• 1415559-08-8 4-benzyl-5-{[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-4H-1,2,4-triazole-3(2H)-thione 
• 1415559-09-9 4-(4-methoxybenzyl)-5-{[(4,5-diphenyl-4H-1,2,4-triazol-3-yl)sulfanyl]methyl}-4H-1,2,4-triazole-3(2H)-thione 
• 1415559-10-2 C₁₉H₁₈N₆S₂ 
• 1415559-11-3 C₂₀H₁₈N₆S₂ 
• 1415559-12-4 C₂₃H₂₄N₆S₂ 

Relevant articles and documents

Synthesis and characterisation of some coumarin-1,2,4-triazol-3-thioether hybrid molecules

A new series of N′-{[(4-methyl/phenyl-5-phenyl-4H-1,2,4-triazol-3-yl)thio]acetyl}-2-oxo-2H-chromene-3-carbohydrazides was synthesised via the reaction of 2-[(4-methyl/phenyl-5-phenyl-4H-1,2,4-triazol-3-yl)thio]acetohydrazides and 3-(1H-benzotriazol-1-ylcarbonyl)-2H-chromen-2-ones in good yields.

Synthesis and Antimicrobial Evaluation of New Schiff Base Hydrazones Bearing 1,2,4-Triazole Moiety

This study presents the synthesis and spectral analysis of new Schiff base hydrazone derivatives. New compounds were prepared by the reaction of [(4-phenyl-5-substituted-4H-1,2,4-triazol-3-yl)sulfanyl] acetohydrazide with various aldehydes. The structures

Synthesis and antimicrobial evaluation of some novel 1,2,4-triazole and 1,3,4-thiadiazole derivatives

This study presents the synthesis and spectral analysis of new derivatives of 1,2,4-triazole-3-thione and 1,3,4-thiadiazole. New compounds were prepared by cyclization reaction of acyl thiosemicarbazide derivatives in the presence of alkaline and acidic media. All synthesized compounds were screened for their in vitro antibacterial activity by using the agar dilution technique. Six of the compounds had potential activity against Gram-positive bacteria (minimal inhibitory concentration [MIC] = 15.63-500 μg/mL). Some compounds showed good activity especially against Bacillus subtilis ATCC 6633 (MIC = 15.63-250 μg/mL), Staphylococcus aureus ATCC 25923 (MIC = 31.25-250 μg/mL), and Micrococcus luteus ATCC 10240 (MIC = 125-250 μg/mL).