60300-84-7

Basic information

• Product Name: Benzeneacetic acid, a-(phenylmethoxy)-, methyl ester
• CAS NO: 60300-84-7
• Molecular Formula: C16H16O3
• Molecular Weight: 256.301
• Mol File: 60300-84-7.mol
• Article Data: 14

Chemical Properties

• CAS DataBase Reference: Benzeneacetic acid, a-(phenylmethoxy)-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, a-(phenylmethoxy)-, methyl ester(60300-84-7)
• EPA Substance Registry System: Benzeneacetic acid, a-(phenylmethoxy)-, methyl ester(60300-84-7)

Safety Data

• Hazardous Substances Data: 60300-84-7(Hazardous Substances Data)

Upstream product

• 15206-55-0 methyl 2-oxo-2-phenylacetate 
• 22979-35-7 Methyl phenyldiazoacetate 
• 100-51-6 benzyl alcohol 
• 455-19-6 4-Trifluoromethylbenzaldehyde 
• 600-22-6 pyruvic acid methyl ester 
• 37542-28-2 methyl (p-chlorphenyl)glyoxylate 
• 57699-28-2 methyl 4-bromophenylglyoxalate 
• 34966-49-9 methyl 2-chlorobenzoylformate 
• 57699-27-1 methyl p-nitrophenylglyoxylate 
• 34966-50-2 methyl 2-(3-chlorophenyl)-2-oxoacetate 
• 32766-61-3 4-methoxyphenylglyoxylate methyl ester 
• 107969-78-8 methyl benzylidenepyruvate 
• 555-16-8 4-nitrobenzaldehdye 
• 100-52-7 benzaldehyde 

Downstream Products

• 91121-63-0 α-benzyloxyphenylacetic acid 

Relevant articles and documents

A gold(i)-catalysed three-component reaction: Via trapping oxonium ylides with allenamides

A gold(i)-catalysed three-component reaction between alcohols (and water), α-aryl-α-diazoesters and allenamides has been developed, affording three-component products, tert-allylic ethers (and alcohols), in moderate to excellent yields with excellent geom

Asymmetric Counter-Anion-Directed Aminomethylation: Synthesis of Chiral β-Amino Acids via Trapping of an Enol Intermediate

A novel enantioselective aminomethylation reaction of diazo compound, alcohol and α-aminomethyl ether enabled by asymmetric counteranion-directed catalysis is disclosed that offers an efficient and convenient access to furnish optically active α-hydroxyl-β-amino acids in high yield with high to excellent enantioselectivities. Control experiments and DFT calculations indicate that the transformation proceeds through trapping the in situ generated enol intermediate with methylene iminium ion, and the asymmetric induction was enabled by chiral pentacarboxycyclopentadiene anion via H-bonding and electrostatic interaction.

Silica-supported HClO4 promotes catalytic solvent- and metal-free O-H insertion reactions with diazo compounds

Solvent-free O-H insertion reactions in the presence of diazo carbonyl compounds were carried-out in very mild conditions. Unlike the traditional metal-catalysed version, employing rhodium acetate dimer, this method uses eco-friendly silica-supported HClO4 as the catalyst. Only 0.3 mol% of this Br?nsted acid catalyst, that can also be recycled several times, is necessary to guarantee very good yields (up to 97%) in the O-H insertion reactions. Reaction set-up is simple and permitted the preparation of forty-three α-hydroxy and α-alkoxy esters/ketones in just 1 h and at room temperature.