619-65-8Relevant articles and documents
1,2-Dibutoxyethane-Promoted Oxidative Cleavage of Olefins into Carboxylic Acids Using O2 under Clean Conditions
Ou, Jinhua,Tan, Hong,He, Saiyu,Wang, Wei,Hu, Bonian,Yu, Gang,Liu, Kaijian
, p. 14974 - 14982 (2021/10/25)
Herein, we report the first example of an effective and green approach for the oxidative cleavage of olefins to carboxylic acids using a 1,2-dibutoxyethane/O2 system under clean conditions. This novel oxidation system also has excellent functional-group tolerance and is applicable for large-scale synthesis. The target products were prepared in good to excellent yields by a one-pot sequential transformation without an external initiator, catalyst, and additive.
Method for preparing methyl 4-cyanobenzoate and method for preparing 4-cyanobenzoic acid
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, (2021/06/09)
The invention relates to the field of synthesis, and discloses a method for preparing methyl 4-cyanobenzoate and a method for preparing 4-cyanobenzoic acid. The method for preparing methyl 4-cyanobenzoate comprises the following steps: (1) in the presence of a first alkaline substance, carrying out a first hydrolysis reaction on dimethyl terephthalate to obtain monomethyl terephthalate; (2) subjecting the monomethyl terephthalate to a contact reaction with a chlorination reagent and ammonia water in sequence so as to obtain methyl 4-carbamoylbenzoate; and (3) carrying out a dehydration reaction on the methyl 4-carbamoylbenzoate to obtain the methyl 4-cyanobenzoate. According to the method for preparing the methyl 4-cyanobenzoate and the method for preparing the 4-cyanobenzoic acid, reaction raw materials are cheap and easy to obtain, and the target compounds can be efficiently prepared in an environment-friendly mode through the processes of hydrolysis, ammoniation, dehydration, optional selection and further hydrolysis.
Photo-induced deep aerobic oxidation of alkyl aromatics
Wang, Chang-Cheng,Zhang, Guo-Xiang,Zuo, Zhi-Wei,Zeng, Rong,Zhai, Dan-Dan,Liu, Feng,Shi, Zhang-Jie
, p. 1487 - 1492 (2021/07/10)
Oxidation is a major chemical process to produce oxygenated chemicals in both nature and the chemical industry. Presently, the industrial manufacture of benzoic acids and benzene polycarboxylic acids (BPCAs) is mainly based on the deep oxidation of polyalkyl benzene, which is somewhat suffering from environmental and economical disadvantage due to the formation of ozone-depleting MeBr and corrosion hazards of production equipment. In this report, photo-induced deep aerobic oxidation of (poly)alkyl benzene to benzene (poly)carboxylic acids was developed. CeCl3 was proved to be an efficient HAT (hydrogen atom transfer) catalyst in the presence of alcohol as both hydrogen and electron shuttle. Dioxygen (O2) was found as a sole terminal oxidant. In most cases, pure products were easily isolated by simple filtration, implying large-scale implementation advantages. The reaction provides an ideal protocol to produce valuable fine chemicals from naturally abundant petroleum feedstocks. [Figure not available: see fulltext.].