Basic information
- Name:
Mesitylene
- CAS No.:
108-67-8
- Molecular Structure:

- Formula:
- C9H12
- Synonyms:
- Mesitylene(8CI);1,3,5-Trimethylbenzene;2,4,6-Trimethylbenzene;3,5-Dimethyltoluene;NSC9273;sym-Trimethylbenzene;
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Chemistry
Molecular structure of Mesitylene (CAS NO.108-67-8) is:

Product Name: Mesitylene
CAS Registry Number: 108-67-8
IUPAC Name: 1,3,5-trimethylbenzene
Molecular Weight: 120.19158 [g/mol]
Molecular Formula: C9H12
XLogP3: 3.4
EINECS: 203-604-4
Melting Point: -45 °C
Water Solubility: 2.9 g/L (20 °C)
Surface Tension: 28.7 dyne/cm
Refractive index: n20/D 1.499(lit.)
Density: 0.869 g/cm3
Flash Point: 44.4 °C
Enthalpy of Vaporization: 38.66 kJ/mol
Boiling Point: 166.7 °C at 760 mmHg
Vapour Pressure: 2.32 mmHg at 25°C
Stability: Stable. Combustible. Incompatible with strong oxidizing agents.
Product Categories: Benzene derivates;Analytical Chemistry;Standard Solution of Volatile Organic Compounds for Water & Soil Analysis;Standard Solutions (VOC)
Uses
Mesitylene (CAS NO.108-67-8) is used in the production of trimesic acid and antioxygen, epoxy firming agent, polyester resin stabilizer, alkyd resin plasticizers and dye. It is commonly used as a solvent in research and industry. In the electronics industry,it has also been used as a developer for photopatternable silicones due to its solvent properties.
Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| guinea pig | LDLo | intraperitoneal | 1303mg/kg (1303mg/kg) | AMA Archives of Industrial Hygiene and Occupational Medicine. Vol. 9, Pg. 227, 1954. | |
| human | TCLo | inhalation | 10ppm (10ppm) | PERIPHERAL NERVE AND SENSATION: SENSORY CHANGE INVOLVING PERIPHERAL NERVE BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: STRUCTURAL OR FUNCTIONAL CHANGE IN TRACHEA OR BRONCHI | Zeitschrift fuer Unfallmedizin und Berufskrankheiten. Revue de Medecine des Accidents et des Maladies Professionelles. Vol. 49, Pg. 265, 1956. |
| rat | LC50 | inhalation | 24gm/m3/4H (24000mg/m3) | Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 44(5), Pg. 15, 1979. |
Safety Profile
Poison by inhalation. Moderately toxic by intraperitoneal route. Human systemic effects by inhalation: sensory changes involving peripheral nerves, somnolence (general depressed activity), and structural or functional change in trachea or bronchi. Reports of leukopenia and thrombocytopenia in experimental animals. A mild skin and eye irritant. A flammable liquid when exposed to heat or flame; can react vigorously with oxidizing materials. Violent reaction with HNO3. To fight fire, use water spray, fog, foam, CO2. Emitted from modern building materials ( CENEAR Chemical and Engineering News. 69 (1991),22. ). When heated to decomposition it emits acrid smoke and irritating fumes.
Hazard Codes:
Xi,
N,
F,
T
Risk Statements: 10-37-51/53-39/23/24/25-23/24/25-11
10: Flammable
37: Irritating to the respiratory system
51/53: Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment
39/23/24/25: Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed
23/24/25: Toxic by inhalation, in contact with skin and if swallowed
11: Highly Flammable
Safety Statements: 61-45-36/37-16-7
61: Avoid release to the environment. Refer to special instructions safety data sheet
45: In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
36/37: Wear suitable protective clothing and gloves
16: Keep away from sources of ignition - No smoking
7: Keep container tightly closed
RIDADR: UN 2325 3/PG 3
WGK Germany: 2
RTECS: OX6825000
F: 10: Keep under argon.
Hazard Note: Irritant/Flammable
HazardClass: 3
PackingGroup: III
HS Code: 29029080
Standards and Recommendations
OSHA PEL: TWA 25 ppm
ACGIH TLV: TWA 25 ppm
DFG MAK: 20 ppm
DOT Classification: 3; Label: Flammable Liquid
Analytical Methods
Mesitylene (CAS NO.108-67-8) is prepared by distillation of acetone with sulfuric acid or by trimerization of propyne in sulfuric acid, which, in both cases, acts as a catalyst and dehydrating agent.
Specification
Mesitylene , its cas register number is 108-67-8. It also can be called 1,3,5-Trimethylbenzene ; 3,5-Dimethyltoluene ; Benzene, 1,3,5-trimethyl- ; Fleet-X ; Trimethylbenzol ; sym-Trimethylbenzene .It is a colorless liquid with a peculiar odor. It insoluble in water and less dense than water. It may be toxic by ingestion and inhalation.
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