Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

1-(3-Aminopropyl)-2-pyrrolidinone
Related Products

Hot Products

Basic Information Post buying leads Suppliers Cas Database
Name

1-(3-Aminopropyl)-2-pyrrolidinone

 EINECS N/A
CAS No. 7663-77-6 Density 1.06g/cm3
PSA 46.33000 LogP 0.59580
Solubility N/A Melting Point N/A
Formula C7H14 N2 O Boiling Point 312°Cat760mmHg
Molecular Weight 142.201 Flash Point 132.4°C
Transport Information N/A Appearance Clear Slightly Yellowish Liquid
Safety Risk Codes 34
Molecular Structure Molecular Structure of 7663-77-6 (1-(3-AMINOPROPYL)-2-PYRROLIDINONE) Hazard Symbols C,Xi
Synonyms

1-(3-Aminopropyl)-2-oxopyrrolidine;1-(3-Aminopropyl)-2-pyrrolidinone; 1-(3-Aminopropyl)-2-pyrrolidone;1-(3-Aminopropyl)pyrrolidin-2-one; 3-(2-Oxo-1-pyrrolidinyl)propylamine;Acisoga; N-(3-Aminopropyl)-2-pyrrolidinone; N-(3-Aminopropyl)-2-pyrrolidone;N-(3-Aminopropyl)-g-butyrolactam; NSC 108683; [3-(2-Oxopyrrolidino)propyl]amine

Article Data 12

1-(3-Aminopropyl)-2-pyrrolidinone Synthetic route

3001-72-7

DBN

7663-77-6

1-(3-aminopropyl)-2-pyrrolidone

Conditions
ConditionsYield
With water at 85℃; for 12h;98%
With water at 85℃; for 12h;
With water at 20℃; for 12h;
With water In water-d2 at 27℃; Kinetics;
201230-82-2

carbon monoxide

34155-45-8

N-allyl-1,3-diaminopropane

A

7663-77-6

1-(3-aminopropyl)-2-pyrrolidone

B

57672-23-8

octahydropyrrolo[1,2-a]pyrimidine

Conditions
ConditionsYield
With hydrogen; dirhodium tetraacetate In benzene at 80℃; under 20685.9 Torr; for 20h; Product distribution; PPh3 and other ligands;A 90%
B 10%
With dirhodium tetraacetate; hydrogen; triphenylphosphine In benzene at 80℃; under 20685.9 Torr; for 20h;
With dirhodium tetraacetate; hydrogen; tris-(o-tolyl)phosphine In benzene at 80℃; under 20685.9 Torr; for 20h; Product distribution; influence of gas composition, type of ligand;
With dirhodium tetraacetate; tributylphosphine; hydrogen In benzene at 80℃; under 20685.9 Torr; for 20h;
107-13-1

acrylonitrile

56-12-2

4-amino-n-butyric acid

7663-77-6

1-(3-aminopropyl)-2-pyrrolidone

Conditions
ConditionsYield
With water at 120℃; Hydrieren des Reaktionsgemisches an Raney-Kobalt bei 120grad/200at.;
616-45-5

2-pyrrolidinon

5003-71-4

3-bromopropylamine hydrochloride

7663-77-6

1-(3-aminopropyl)-2-pyrrolidone

Conditions
ConditionsYield
With sodium hydride In N,N-dimethyl-formamide
34508-81-1

3-[(prop-2-en-1-yl)amino]propanenitrile

7663-77-6

1-(3-aminopropyl)-2-pyrrolidone

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: 70 percent / LiAlH4
2: H2, P(n-Bu)3, rhodium(II) acetate dimer / benzene / 20 h / 80 °C / 20685.9 Torr
View Scheme
84598-48-1

2-[3-(2-Oxo-pyrrolidin-1-yl)-propyl]-isoindole-1,3-dione

7663-77-6

1-(3-aminopropyl)-2-pyrrolidone

Conditions
ConditionsYield
With hydrazine hydrate
7663-77-6

1-(3-aminopropyl)-2-pyrrolidone

194996-03-7

2-([(tert-butoxy)carbonyl]{2-[(4-methoxybenzyl)amino]-2-oxoethyl}amino)acetic acid

194996-16-2

[(4-Methoxy-benzylcarbamoyl)-methyl]-{[3-(2-oxo-pyrrolidin-1-yl)-propylcarbamoyl]-methyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h; Substitution;100%
With N,N-diethyl-N-isopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 25℃; for 16h;27%
7663-77-6

1-(3-aminopropyl)-2-pyrrolidone

188625-17-4

N-((tert-butyloxy)carbonyl)-N'-(2-(4-fluorophenyl)ethyl)iminodiacetic acid monoamide

194996-17-3

N-((tert-butoxy)carbonyl)-N'-(2-(4-fluorophenyl)ethyl)-N''-(3-(N-pyrrolidin-2-onyl)propyl)iminodiacetic acid diamide

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h; Substitution;100%
With N,N-diethyl-N-isopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 25℃; for 16h;18%
7663-77-6

1-(3-aminopropyl)-2-pyrrolidone

194996-01-5

N-((tert-butyloxy)carbonyl)-N'-(2-(4-hydroxyphenyl)ethyl)iminodiacetic acid monoamide

194996-14-0

{[2-(4-Hydroxy-phenyl)-ethylcarbamoyl]-methyl}-{[3-(2-oxo-pyrrolidin-1-yl)-propylcarbamoyl]-methyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h; Substitution;100%
With N,N-diethyl-N-isopropylamine; benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate In N,N-dimethyl-formamide at 25℃; for 16h;9%
7663-77-6

1-(3-aminopropyl)-2-pyrrolidone

215161-22-1

N-((tert-butyloxy)carbonyl)-N'-(4-(1',4'-dioxolano)piperidino)iminodiacetic acid monoamide

[2-(1,4-dioxa-8-aza-spiro[4.5]dec-8-yl)-2-oxo-ethyl]-{[3-(2-oxo-pyrrolidin-1-yl)-propylcarbamoyl]-methyl}-carbamic acid tert-butyl ester

Conditions
ConditionsYield
With benzotriazol-1-yloxyl-tris-(pyrrolidino)-phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine In N,N-dimethyl-formamide at 25℃; for 16h; Substitution;100%

1-(3-Aminopropyl)-2-pyrrolidinone Chemical Properties

Molecular Structure:

Molecular Formula: C7H14N2O
Molecular Weight: 142.1989
IUPAC Name: 1-(3-Aminopropyl)pyrrolidin-2-one
Synonyms of 1-(3-Aminopropyl)-2-pyrrolidinone (CAS NO.7663-77-6): 4-21-00-03163 (Beilstein Handbook Reference) ; BRN 0114960 ; EINECS 231-632-7 ; N-(3-Aminopropyl)-2-pyrrolidinone ; NSC 108683 ; 2-Pyrrolidinone, 1-(3-aminopropyl)- ; N-(3-Aminopropyl)pyrrolidin-2-one
CAS NO: 7663-77-6
Classification Code: Miscellaneous Reagents ; Synthetic Intermediates ; Building Blocks ; Heterocyclic Building Blocks ; Pyrrolidines 
Index of Refraction: 1.503
Molar Refractivity: 39.63 cm3
Molar Volume: 134 cm3
Surface Tension: 42.3 dyne/cm
Density: 1.06 g/cm3
Flash Point: 132.4 °C
Enthalpy of Vaporization: 55.29 kJ/mol
Boiling Point: 312 °C at 760 mmHg
Vapour Pressure: 0.000545 mmHg at 25°C

1-(3-Aminopropyl)-2-pyrrolidinone Uses

  1-(3-Aminopropyl)-2-pyrrolidinone (CAS NO.7663-77-6) is used as synthetic intermediate.

1-(3-Aminopropyl)-2-pyrrolidinone Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 320mg/kg (320mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#05698,
mouse LDLo oral 1600mg/kg (1600mg/kg)   Archives of Environmental Contamination and Toxicology. Vol. 14, Pg. 111, 1985.

1-(3-Aminopropyl)-2-pyrrolidinone Safety Profile

Hazard Codes of 1-(3-Aminopropyl)-2-pyrrolidinone (CAS NO.7663-77-6): CorrosiveC,IrritantXi
Risk Statements: 34 
R34: Causes burns.
Safety Statements: 26-27-36/37/39-45 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S27: Take off immediately all contaminated clothing. 
S36/37/39: Wear suitable protective clothing, gloves and eye/face protection. 
S45: In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)
RIDADR: UN 3267 8/PG 2
WGK Germany: 3
RTECS: UY5739500
F: 9-34
Hazard Note: Irritant

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 7663-77-6