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Name	1-(tert-Butylamino)-3-(2-chloro-5-methyl phenoxy)-2-propanol hydro-chloride	EINECS	N/A
CAS No.	15148-80-8	Density	1.098g/cm³
PSA	41.49000	LogP	3.96910
Solubility	N/A	Melting Point	220-222°
Formula	C14H22 Cl N O2 . Cl H	Boiling Point	396.3°Cat760mmHg
Molecular Weight	308.24392	Flash Point	193.5°C
Transport Information	N/A	Appearance	N/A
Safety	Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NO_x and Cl⁻.	Risk Codes	N/A
Molecular Structure		Hazard Symbols	N/A
Synonyms	2-Propanol,1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-, hydrochloride(9CI); 2-Propanol, 1-(tert-butylamino)-3-[(6-chloro-m-tolyl)oxy]-,hydrochloride (8CI); (-)-KL 255; (?à)-Kl 255; 1-(6'-Chloro-3'-methylphenoxy)-3-tert-butylaminopropanol,hydrochloride; 1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)-2-propanolhydrochloride; 1-tert-Butylamino-3-(6-chloro-m-tolyloxy)-2-propanolhydrochloride; 3-tert-Butylamino-1-(6-chloro-3-methylphenoxy)propan-2-olhydrochloride; B 1312; Betadran; Betadrenol; Betadrenol hydrochloride;Bupranolol hydrochloride; KL 255; Looser; Panimit; SKF 16805A; dl-Bupranololhydrochloride; dl-KL 255

1-(tert-Butylamino)-3-(2-chloro-5-methyl phenoxy)-2-propanol hydro-chloride Chemical Properties

IUPAC Name: 1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)propan-2-ol hydrochloride
Synonyms: 1-(tert-Butylamino)-3-(2-chloro-5-methylphenoxy)propan-2-ol hydrochloride (1:1) ; 2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-((1,1-dimethylethyl)amino)-, hydrochloride, (+-)- ; 2-Propanol, 1-(2-chloro-5-methylphenoxy)-3-[(1,1-dimethylethyl)amino]-, hydrochloride (1:1) ; 2-Propanol, 1-tert-butylamino-3-(6-chloro-m-tolyloxy)-, hydrochloride
CAS NO:15148-80-8
Molecular Formula of 1-(tert-Butylamino)-3-(2-chloro-5-methyl phenoxy)-2-propanol hydro-chloride (CAS NO.15148-80-8) : C₁₄H₂₃Cl₂NO₂
Molecular Weight of 1-(tert-Butylamino)-3-(2-chloro-5-methyl phenoxy)-2-propanol hydro-chloride (CAS NO.15148-80-8) :308.24392
Molecular Structure of 1-(tert-Butylamino)-3-(2-chloro-5-methyl phenoxy)-2-propanol hydro-chloride (CAS NO.15148-80-8) :
EINECS: 239-208-3
Flash Point: 193.5 °C
Enthalpy of Vaporization: 68.19 kJ/mol
Boiling Point: 396.3 °C at 760 mmHg
Vapour Pressure: 5.44E-07 mmHg at 25°C

1-(tert-Butylamino)-3-(2-chloro-5-methyl phenoxy)-2-propanol hydro-chloride Toxicity Data With Reference

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
dog	LD50	oral	438mg/kg (438mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 75, 1973.
mouse	LD50	intravenous	39300ug/kg (39.3mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 75, 1973.
mouse	LD50	oral	329mg/kg (329mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 75, 1973.
mouse	LD50	subcutaneous	567mg/kg (567mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 75, 1973.
rabbit	LD50	intravenous	15300ug/kg (15.3mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 75, 1973.
rabbit	LD50	oral	895mg/kg (895mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 75, 1973.
rat	LD50	intraperitoneal	96mg/kg (96mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 75, 1973.
rat	LD50	intravenous	15300ug/kg (15.3mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) LUNGS, THORAX, OR RESPIRATION: CHRONIC PULMONARY EDEMA LUNGS, THORAX, OR RESPIRATION: DYSPNEA	Yakkyoku. Pharmacy. Vol. 25, Pg. 813, 1974.
rat	LD50	oral	518mg/kg (518mg/kg)	BEHAVIORAL: SOMNOLENCE (GENERAL DEPRESSED ACTIVITY) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 75, 1973.
rat	LD50	subcutaneous	630mg/kg (630mg/kg)	BEHAVIORAL: ALTERED SLEEP TIME (INCLUDING CHANGE IN RIGHTING REFLEX) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD LUNGS, THORAX, OR RESPIRATION: RESPIRATORY DEPRESSION	Oyo Yakuri. Pharmacometrics. Vol. 7, Pg. 75, 1973.

1-(tert-Butylamino)-3-(2-chloro-5-methyl phenoxy)-2-propanol hydro-chloride Safety Profile

Poison by ingestion, intraperitoneal, and intravenous routes. Moderately toxic by subcutaneous route. An experimental teratogen. Other experimental reproductive effects. When heated to decomposition it emits very toxic fumes of NO_x and Cl⁻.

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