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1,10-Diaminodecane

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Name

1,10-Diaminodecane

EINECS 211-471-9
CAS No. 646-25-3 Density 0.857 g/cm3
PSA 52.04000 LogP 3.42520
Solubility 5.9g/L at 20℃ Melting Point 62 °C
Formula C10H24 N2 Boiling Point 140 °C12 mm Hg(lit.)
Molecular Weight 172.314 Flash Point 127.1°C
Transport Information UN 3259 8 Appearance white to light yellow powder and chunks
Safety Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx. Risk Codes 34-37
Molecular Structure Molecular Structure of 646-25-3 (1,10-Diaminodecane) Hazard Symbols CorrosiveC
Synonyms

1,10-Decamethylenediamine;1,10-Decylenediamine;1,10-Diamino-n-decane;1,10-Diaminodecane;1,6-Decanediamine;Decamethylenediamine;NCI 10400;NSC 10400;

Article Data 50

1,10-Diaminodecane Chemical Properties

IUPAC Name: 1,10-Diaminodecane
The MF of 1,10-Diaminodecane (646-25-3) is C10H24N2.

         
The MW of 1,10-Diaminodecane (646-25-3) is 172.31.
Synonyms of 1,10-Diaminodecane (646-25-3): 1,10-Decanediamine ; Decan-1,10-diamin ; 1,10-Decamethylenediamine ; 1,10-Diaminodecane ; Decyldiamine
Product Categories: Aromatic Esters;alpha,omega-Alkanediamines;alpha,omega-Bifunctional Alkanes;Monofunctional & alpha,omega-Bifunctional Alkanes
Form: white to light yellow chunks or powder
Index of Refraction: 1.463 
EINECS: 211-471-9
Density: 0.857 g/ml 
Flash Point: 127.1 °C
Boiling Point: 271.1 °C
Melting Point: 62 °C

1,10-Diaminodecane Uses

  1,10-Diaminodecane (646-25-3) is used as a raw material in organic synthesis for polymerization of polymers and drugs refined, as well as reagents.

1,10-Diaminodecane Production

It derived from Nitrile by the catalytic hydrogenation sebacate. To 1,10 - sebacic nitrile and suspended in 95% ethanol in the Raney nickel catalyst loading capacity of 1.1L high-pressure reactor, which leads to ammonia, and then pass into the hydrogen to the pressure 10.34MPa, heating to 125 ℃ to no longer absorb hydrogen when cooled, so that hydrogen and ammonia Yi to go. Pass into the alcohol washing out of the reactor in the reaction products, and then ethanol decolorization filter to remove the catalyst, and then to the ethanol steam pressure often conducted after the vacuum distillation, collecting 143-146 ℃ (1.867kPa) fraction derived from 1,10 -- Kuei-diamine product. In addition, sebacic alcohol as raw materials in order to Raney nickel as a catalyst at 220-260 ℃ under can be obtained catalytic amination of 1,10 - Kuei-diamine.

1,10-Diaminodecane Toxicity Data With Reference

1.    

orl-rat LDLo:500 mg/kg

    JPETAB    Journal of Pharmacology and Experimental Therapeutics. 90 (1947),260.
2.    

ipr-mus LDLo:125 mg/kg

    CBCCT*    “Summary Tables of Biological Tests“ National Research Council Chemical-Biological Coordination Center. 4 (1952),377.

1,10-Diaminodecane Consensus Reports

Reported in EPA TSCA Inventory.

1,10-Diaminodecane Safety Profile

Poison by intraperitoneal route. Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.Safety information of 1,10-Diaminodecane (646-25-3):
Hazard Codes  C
Risk Statements 
34  Causes burns
37  Irritating to the respiratory system
Safety Statements 
26  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39  Wear suitable protective clothing, gloves and eye/face protection
45  In case of accident or if you feel unwell, seek medical advice immediately (show label where possible)
RIDADR  UN 3259 8/PG 3
WGK Germany  3
RTECS  HD7175000
F  10-34

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