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10,11-Dehydroimipramine

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Name

10,11-Dehydroimipramine

EINECS
CAS No. 303-54-8 Density 1.06g/cm3
Solubility Melting Point
Formula C19H22 N2 Boiling Point 413.9°Cat760mmHg
Molecular Weight 278.43 Flash Point 185.9°C
Transport Information Appearance
Safety Poison by intravenous route. When heated to decomposition it emits toxic fumes of NOx. Risk Codes
Molecular Structure Molecular Structure of 303-54-8 (10,11-Dehydroimipramine) Hazard Symbols
Synonyms

5H-Dibenz[b,f]azepine,5-[3-(dimethylamino)propyl]- (6CI,7CI,8CI); 10,11-Dehydroimipramine;5-[3-(Dimethylamino)propyl]-5H-dibenz[b,f]azepine; Balipramine; Depramine; G31406; GP 31406

 

10,11-Dehydroimipramine Chemical Properties

Molecular structure of 10,11-Dehydroimipramine (CAS NO.303-54-8) is:

Product Name: 10,11-Dehydroimipramine
CAS Registry Number: 303-54-8
IUPAC Name: 3-benzo[b][1]benzazepin-11-yl-N,N-dimethylpropan-1-amine
Molecular Weight: 278.39138 [g/mol]
Molecular Formula: C19H22N2
XLogP3: 5
H-Bond Donor: 0
H-Bond Acceptor: 2
Surface Tension: 41.2 dyne/cm
Density: 1.06 g/cm3
Flash Point: 185.9 °C
Enthalpy of Vaporization: 66.67 kJ/mol
Boiling Point: 413.9 °C at 760 mmHg
Vapour Pressure: 4.64E-07 mmHg at 25°C 
Related Registry Number: 58262-51-4 (hydrochloride) ; 72629-48-2 (fumarate[1:1])

10,11-Dehydroimipramine Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 41mg/kg (41mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 120, Pg. 450, 1959.
rabbit LD50 intravenous 6mg/kg (6mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 120, Pg. 450, 1959.
rat LD50 intravenous 23mg/kg (23mg/kg)   Archives Internationales de Pharmacodynamie et de Therapie. Vol. 120, Pg. 450, 1959.

10,11-Dehydroimipramine Safety Profile

Poison by intravenous route. When heated to decomposition it emits toxic fumes of NOx.

10,11-Dehydroimipramine Specification

 10,11-Dehydroimipramine , its cas register number is 303-54-8. It also can be called Depramine [INN] ; 10,11-Dehydroimipramine ; 5-(3-(Dimethylamino)propyl)-5H-dibenz(b,f)azepine ; 5-20-08-00247 (Beilstein Handbook Reference) ; BRN 1319717 ; Balipramine ; Depramina ; Depramina [INN-Spanish] ; Depramine ; Depraminum ; Depraminum [INN-Latin] ; GP 31406 ; UNII-77C3T28736 ; 5-(3-(Dimethylamino)propyl)-5H-dibenz(b,f)azepine ; 5H-Dibenz(b,f)azepine, 5-(3-(dimethylamino)propyl)- ; 5H-Dibenz(b,f)azepine-5-propanamine, N,N-dimethyl- (9CI) .

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