The Benzene,1,4-bis(trifluoromethyl)-, with CAS registry number 433-19-2, has the systematic name of 1,4-bis(trifluoromethyl)benzene. This chemical is a kind of clear colorless liquid. The main use of this chemical is for the medicines intermediates. What's more, its EINECS is 207-086-0.

Physical properties of Benzene,1,4-bis(trifluoromethyl)-: (1)ACD/LogP: 3.83; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): 3.83; (4)ACD/LogD (pH 7.4): 3.83; (5)ACD/BCF (pH 5.5): 479.51; (6)ACD/BCF (pH 7.4): 479.51; (7)ACD/KOC (pH 5.5): 2887.49; (8)ACD/KOC (pH 7.4): 2887.49; (9)#H bond acceptors: 0; (10)#H bond donors: 0; (11)#Freely Rotating Bonds: 0; (12)Polar Surface Area: 0 Å²; (13)Index of Refraction: 1.379; (14)Molar Refractivity: 36.21 cm³; (15)Molar Volume: 156.4 cm³; (16)Polarizability: 14.35×10^-24cm³; (17)Surface Tension: 17.8 dyne/cm; (18)Enthalpy of Vaporization: 33.97 kJ/mol; (19)Vapour Pressure: 22.1 mmHg at 25°C.

Preparation: this chemical can be prepared by 1,4-diiodo-benzene and difluoro-(1,1,2,2-tetrafluoro-2-fluorosulfonyl-ethoxy)-acetic acid methyl ester. This reaction will need reagent CuI and solvent dimethylformamide. The reaction time is 8 hour(s) with reaction temperature of 100 ℃. The yield is about 62%.

Uses of Benzene,1,4-bis(trifluoromethyl)-: it can be used to produce 1,4-dibromo-2,5-bis-trifluoromethyl-benzene and 2-bromo-1,4-bis-trifluoromethyl-benzene. This reaction will need reagents antimony (V)-chloride, chlorine, bromine. The reaction temperature is 125 ℃.

When you are using this chemical, please be cautious about it as the following:
The Benzene,1,4-bis(trifluoromethyl)- is flammable, so keep it away from sources of ignition. This chemical also irritates to eyes, respiratory system and skin. When use it, wear suitable protective clothing, gloves and eye/face protection. If contact with eyes, rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: FC(F)(F)c1ccc(cc1)C(F)(F)F
(2)InChI: InChI=1/C8H4F6/c9-7(10,11)5-1-2-6(4-3-5)8(12,13)14/h1-4H
(3)InChIKey: PDCBZHHORLHNCZ-UHFFFAOYAY
(4)Std. InChI: InChI=1S/C8H4F6/c9-7(10,11)5-1-2-6(4-3-5)8(12,13)14/h1-4H
(5)Std. InChIKey: PDCBZHHORLHNCZ-UHFFFAOYSA-N