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Name	1-Hydroxy-2-naphthoic acid	EINECS	201-674-0
CAS No.	86-48-6	Density	1.399 g/cm³
PSA	57.53000	LogP	2.24360
Solubility	soluble in hot water	Melting Point	195-200 °C (dec.)(lit.)
Formula	C₁₁H₈O₃	Boiling Point	367.7 °C at 760 mmHg
Molecular Weight	188.183	Flash Point	190.4 °C
Transport Information	N/A	Appearance	beige to brown-grey powder
Safety	26-36-37/39	Risk Codes	36/37/38
Molecular Structure		Hazard Symbols	Xi
Synonyms	2-Naphthoicacid, 1-hydroxy- (8CI);1-Hydroxy-2-naphthalenecarboxylic acid;	Article Data	54

1-Hydroxy-2-naphthoic acid Synthetic route

: 90-15-3
α-naphthol

: 4861-79-4
magnesium methyl carbonate

: 86-48-6
1-hydroxy-2-naphthoic acid

Conditions

Conditions	Yield
In N,N-dimethyl-formamide at 180℃; under 25857.4 Torr; for 6h;	96%

: 90-15-3
α-naphthol

: 17201-44-4
sodium ethyl carbonate

: 86-48-6
1-hydroxy-2-naphthoic acid

Conditions

Conditions	Yield
at 140 - 190℃; under 7600 Torr; for 5h;	93.4%

: 90-15-3
α-naphthol

: 86-48-6
1-hydroxy-2-naphthoic acid

Conditions

Conditions	Yield
With potassium hydrogencarbonate at 200℃; for 5h;	60%
With salicylic acid decarboxylase from Trichosporon moniliiforme; potassium hydrogencarbonate In acetonitrile at 30℃; for 24h; pH=8.5; aq. phosphate buffer; Enzymatic reaction; regioselective reaction;
Multi-step reaction with 4 steps 1.1: 1H-imidazole / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C / Inert atmosphere 1.2: 0 - 20 °C / Inert atmosphere 2.1: water; sodium hydrogencarbonate / N,N-dimethyl-formamide; diethyl ether / 0.5 h / 20 °C / Inert atmosphere 3.1: palladium diacetate; silver(I) acetate; N-tert-butoxycarbonyl-L-leucine; 2,2,2-trifluoroethanol / 1,2-dichloro-ethane / 0.08 h / 95 °C / Inert atmosphere 3.2: 18 h / 95 °C / Inert atmosphere 4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / Inert atmosphere View Scheme

: 623-11-0
1-methyl-4-nitrosobenzene

: 858438-04-7
4-isopropyl-benzo[h]chromen-2-one

: 86-48-6
1-hydroxy-2-naphthoic acid

: 1885-78-5
1-nitro-naphthalene-2-carbonitrile

: 86-48-6
1-hydroxy-2-naphthoic acid

Conditions

Conditions	Yield
With barium dihydroxide

: 69796-59-4
3-acetyl-2-methyl-benzo[h]chromen-4-one

: furan-2,3,5(4H)-trione pyridine (1:1)

: 86-48-6
1-hydroxy-2-naphthoic acid

: 67176-26-5
1-hydroxynaphthalene-2-carbonitrile

: 86-48-6
1-hydroxy-2-naphthoic acid

Conditions

Conditions	Yield
With alkaline solution

: 3019-88-3
sodium naphtholate

: 15719-64-9, 15719-76-3, 97762-63-5
methylammonium carbonate

: 86-48-6
1-hydroxy-2-naphthoic acid

Conditions

Conditions	Yield
With 1,4-dioxane
With pyridine

: 2-cyano-naphthalene-1-sulfonic acid ; sodium-salt

: 86-48-6
1-hydroxy-2-naphthoic acid

Conditions

Conditions	Yield
at 200 - 220℃; In der Kalischmelze;

: 104095-33-2
3-benzoyl-5-chloromethyl-dihydro-furan-2-one

: 86-48-6
1-hydroxy-2-naphthoic acid

Conditions

Conditions	Yield
With aluminium trichloride

1-Hydroxy-2-naphthoic acid Chemical Properties

Product Name: 1-Hydroxy-2-naphthoic acid (CAS NO.86-48-6)
IUPAC Name: 1-hydroxynaphthalene-2-carboxylic acid

MF: C₁₁H₈O₃
MW: 188.18
EINECS: 201-674-0
MP: 195-200 °C (dec.)(lit.)
Fp: 150 °C
Density: 1.399 g/cm³
Boiling Point: 367.7 °C at 760 mmHg
Water Solubility: Solubility in hot water
Appearance: Slightly gray granules.
Index of Refraction: 1.716
Molar Refractivity: 52.9 cm³
Molar Volume: 134.5 cm³
Categories: Intermediates of Dyes and Pigments

1-Hydroxy-2-naphthoic acid Uses

1-Hydroxy-2-naphthoic acid (CAS NO.86-48-6) is used as coupler and also used as the additive of battery.

1-Hydroxy-2-naphthoic acid Safety Profile

Safety Information of 1-Hydroxy-2-naphthoic acid (CAS NO.86-48-6):
Hazard Codes: Xi
Risk Statements: 36/37/38
36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-36-37/39
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37/39: Wear suitable gloves and eye/face protection
WGK Germany: 3
HS Code: 29182910

1-Hydroxy-2-naphthoic acid Specification

1-Hydroxy-2-naphthoic acid , its CAS NO. is 86-48-6, the synonyms are 1-hydroxy-2-naphthalenecarboxylicaci ;1-hydroxy-2-Naphthalenecarboxylicacid

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