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Basic Information
CAS No.: 86-48-6
Name: 1-Hydroxy-2-naphthoic acid
Molecular Structure:
Molecular Structure of 86-48-6 (1-Hydroxy-2-naphthoic acid)
Formula: C11H8O3
Molecular Weight: 188.183
Synonyms: 2-Naphthoicacid, 1-hydroxy- (8CI);1-Hydroxy-2-naphthalenecarboxylic acid;
EINECS: 201-674-0
Density: 1.399 g/cm3
Melting Point: 195-200 °C (dec.)(lit.)
Boiling Point: 367.7 °C at 760 mmHg
Flash Point: 190.4 °C
Solubility: soluble in hot water
Appearance: beige to brown-grey powder
Hazard Symbols: IrritantXi
Risk Codes: 36/37/38
Safety: 26-36-37/39
PSA: 57.53000
LogP: 2.24360
Synthetic route
90-15-3

α-naphthol

4861-79-4

magnesium methyl carbonate

86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
In N,N-dimethyl-formamide at 180℃; under 25857.4 Torr; for 6h;96%
90-15-3

α-naphthol

17201-44-4

sodium ethyl carbonate

86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
at 140 - 190℃; under 7600 Torr; for 5h;93.4%
90-15-3

α-naphthol

86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With potassium hydrogencarbonate at 200℃; for 5h;60%
With salicylic acid decarboxylase from Trichosporon moniliiforme; potassium hydrogencarbonate In acetonitrile at 30℃; for 24h; pH=8.5; aq. phosphate buffer; Enzymatic reaction; regioselective reaction;
Multi-step reaction with 4 steps
1.1: 1H-imidazole / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C / Inert atmosphere
1.2: 0 - 20 °C / Inert atmosphere
2.1: water; sodium hydrogencarbonate / N,N-dimethyl-formamide; diethyl ether / 0.5 h / 20 °C / Inert atmosphere
3.1: palladium diacetate; silver(I) acetate; N-tert-butoxycarbonyl-L-leucine; 2,2,2-trifluoroethanol / 1,2-dichloro-ethane / 0.08 h / 95 °C / Inert atmosphere
3.2: 18 h / 95 °C / Inert atmosphere
4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / Inert atmosphere
View Scheme
623-11-0

1-methyl-4-nitrosobenzene

858438-04-7

4-isopropyl-benzo[h]chromen-2-one

86-48-6

1-hydroxy-2-naphthoic acid

1885-78-5

1-nitro-naphthalene-2-carbonitrile

86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With barium dihydroxide
69796-59-4

3-acetyl-2-methyl-benzo[h]chromen-4-one

furan-2,3,5(4H)-trione pyridine (1:1)

86-48-6

1-hydroxy-2-naphthoic acid

67176-26-5

1-hydroxynaphthalene-2-carbonitrile

86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With alkaline solution
3019-88-3

sodium naphtholate

15719-64-9, 15719-76-3, 97762-63-5

methylammonium carbonate

86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With 1,4-dioxane
With pyridine

2-cyano-naphthalene-1-sulfonic acid ; sodium-salt

86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
at 200 - 220℃; In der Kalischmelze;
104095-33-2

3-benzoyl-5-chloromethyl-dihydro-furan-2-one

86-48-6

1-hydroxy-2-naphthoic acid

Conditions
ConditionsYield
With aluminium trichloride
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Chemistry

Product Name: 1-Hydroxy-2-naphthoic acid (CAS NO.86-48-6)
IUPAC Name: 1-hydroxynaphthalene-2-carboxylic acid

MF: C11H8O3
MW: 188.18
EINECS: 201-674-0
MP: 195-200 °C (dec.)(lit.)
Fp: 150 °C
Density: 1.399 g/cm3 
Boiling Point: 367.7 °C at 760 mmHg 
Water Solubility: Solubility in hot water
Appearance: Slightly gray granules.
Index of Refraction: 1.716 
Molar Refractivity: 52.9 cm3 
Molar Volume: 134.5 cm3
Categories: Intermediates of Dyes and Pigments

Uses

 1-Hydroxy-2-naphthoic acid (CAS NO.86-48-6) is used as coupler and also used as the additive of battery.

Safety Profile

Safety Information of 1-Hydroxy-2-naphthoic acid (CAS NO.86-48-6):
Hazard Codes: Xi
Risk Statements: 36/37/38
36/37/38:  Irritating to eyes, respiratory system and skin 
Safety Statements: 26-36-37/39
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing 
37/39:  Wear suitable gloves and eye/face protection 
WGK Germany: 3
HS Code: 29182910

Specification

 1-Hydroxy-2-naphthoic acid , its CAS NO. is 86-48-6, the synonyms are 1-hydroxy-2-naphthalenecarboxylicaci ;1-hydroxy-2-Naphthalenecarboxylicacid