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| CAS No.: | 86-48-6 |
|---|---|
| Name: | 1-Hydroxy-2-naphthoic acid |
| Molecular Structure: | |
|
|
|
| Formula: | C11H8O3 |
| Molecular Weight: | 188.183 |
| Synonyms: | 2-Naphthoicacid, 1-hydroxy- (8CI);1-Hydroxy-2-naphthalenecarboxylic acid; |
| EINECS: | 201-674-0 |
| Density: | 1.399 g/cm3 |
| Melting Point: | 195-200 °C (dec.)(lit.) |
| Boiling Point: | 367.7 °C at 760 mmHg |
| Flash Point: | 190.4 °C |
| Solubility: | soluble in hot water |
| Appearance: | beige to brown-grey powder |
| Hazard Symbols: |
Xi
|
| Risk Codes: | 36/37/38 |
| Safety: | 26-36-37/39 |
| PSA: | 57.53000 |
| LogP: | 2.24360 |

| Conditions | Yield |
|---|---|
| In N,N-dimethyl-formamide at 180℃; under 25857.4 Torr; for 6h; | 96% |

| Conditions | Yield |
|---|---|
| at 140 - 190℃; under 7600 Torr; for 5h; | 93.4% |

| Conditions | Yield |
|---|---|
| With potassium hydrogencarbonate at 200℃; for 5h; | 60% |
| With salicylic acid decarboxylase from Trichosporon moniliiforme; potassium hydrogencarbonate In acetonitrile at 30℃; for 24h; pH=8.5; aq. phosphate buffer; Enzymatic reaction; regioselective reaction; | |
| Multi-step reaction with 4 steps 1.1: 1H-imidazole / N,N-dimethyl-formamide / 0.5 h / 0 - 20 °C / Inert atmosphere 1.2: 0 - 20 °C / Inert atmosphere 2.1: water; sodium hydrogencarbonate / N,N-dimethyl-formamide; diethyl ether / 0.5 h / 20 °C / Inert atmosphere 3.1: palladium diacetate; silver(I) acetate; N-tert-butoxycarbonyl-L-leucine; 2,2,2-trifluoroethanol / 1,2-dichloro-ethane / 0.08 h / 95 °C / Inert atmosphere 3.2: 18 h / 95 °C / Inert atmosphere 4.1: tetrabutyl ammonium fluoride / tetrahydrofuran / 0.5 h / Inert atmosphere View Scheme |

1-methyl-4-nitrosobenzene


4-isopropyl-benzo[h]chromen-2-one


1-hydroxy-2-naphthoic acid

| Conditions | Yield |
|---|---|
| With barium dihydroxide |

3-acetyl-2-methyl-benzo[h]chromen-4-one


1-hydroxy-2-naphthoic acid

1-hydroxynaphthalene-2-carbonitrile


1-hydroxy-2-naphthoic acid

| Conditions | Yield |
|---|---|
| With alkaline solution |

sodium naphtholate


methylammonium carbonate


1-hydroxy-2-naphthoic acid

| Conditions | Yield |
|---|---|
| With 1,4-dioxane | |
| With pyridine |


1-hydroxy-2-naphthoic acid

| Conditions | Yield |
|---|---|
| at 200 - 220℃; In der Kalischmelze; |

3-benzoyl-5-chloromethyl-dihydro-furan-2-one


1-hydroxy-2-naphthoic acid

| Conditions | Yield |
|---|---|
| With aluminium trichloride |
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Product Name: 1-Hydroxy-2-naphthoic acid (CAS NO.86-48-6)
IUPAC Name: 1-hydroxynaphthalene-2-carboxylic acid

MF: C11H8O3
MW: 188.18
EINECS: 201-674-0
MP: 195-200 °C (dec.)(lit.)
Fp: 150 °C
Density: 1.399 g/cm3
Boiling Point: 367.7 °C at 760 mmHg
Water Solubility: Solubility in hot water
Appearance: Slightly gray granules.
Index of Refraction: 1.716
Molar Refractivity: 52.9 cm3
Molar Volume: 134.5 cm3
Categories: Intermediates of Dyes and Pigments
1-Hydroxy-2-naphthoic acid (CAS NO.86-48-6) is used as coupler and also used as the additive of battery.
Safety Information of 1-Hydroxy-2-naphthoic acid (CAS NO.86-48-6):
Hazard Codes:
Xi
Risk Statements: 36/37/38
36/37/38: Irritating to eyes, respiratory system and skin
Safety Statements: 26-36-37/39
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37/39: Wear suitable gloves and eye/face protection
WGK Germany: 3
HS Code: 29182910
1-Hydroxy-2-naphthoic acid , its CAS NO. is 86-48-6, the synonyms are 1-hydroxy-2-naphthalenecarboxylicaci ;1-hydroxy-2-Naphthalenecarboxylicacid