Hot Products

Basic Information

Post buying leads

Suppliers

Cas Database

Name	2',4'-Dichloro-5'-fluoroacetophenone	EINECS	-0
CAS No.	704-10-9	Density	1.388 g/cm³
PSA	17.07000	LogP	3.33510
Solubility	N/A	Melting Point	33-36 °C
Formula	C₈H₅Cl₂FO	Boiling Point	254.9 °C at 760 mmHg
Molecular Weight	207.032	Flash Point	107.9 °C
Transport Information	N/A	Appearance	white to light yellow cryst. low melting solid
Safety	26-36-37/39	Risk Codes	36/37/38
Molecular Structure		Hazard Symbols	Xi,F
Synonyms	Acetophenone,2',4'-dichloro-5'-fluoro- (7CI,8CI);	Article Data	10

2',4'-Dichloro-5'-fluoroacetophenone Synthetic route

: 1435-48-9
1,3-dichloro-4-fluorobenzene

: 75-36-5
acetyl chloride

: 704-10-9
2,4-dichloro-5-fluoroacetophenone

Conditions

Conditions	Yield
With aluminum (III) chloride at 110℃; Reagent/catalyst; Temperature;	89.3%
With aluminum (III) chloride Friedel Crafts acylation;	52%
With aluminum (III) chloride at 30 - 120℃; Product distribution / selectivity;
aluminum (III) chloride

: 1435-48-9
1,3-dichloro-4-fluorobenzene

: 108-24-7
acetic anhydride

: 704-10-9
2,4-dichloro-5-fluoroacetophenone

Conditions

Conditions	Yield
With aluminium trichloride
With aluminum (III) chloride at 70 - 120℃; for 25h;	165 g

: 1-(1-butoxy-vinyl)-2,4-dichloro-5-fluoro-benzene

: 704-10-9
2,4-dichloro-5-fluoroacetophenone

Conditions

Conditions	Yield
With hydrogenchloride for 0.5h;

: 1481-63-6
1-bromo-2,4-dichloro-5-fluorobenzene

: 704-10-9
2,4-dichloro-5-fluoroacetophenone

Conditions

Conditions	Yield
Multi-step reaction with 2 steps 1: 1-butyl-3-methylimidazolium*BF4; 1,3-bis(diphenylphosphino)propane; Et3N / Ni(OAc)2 / 30 h / 130 °C 2: aq. HCl / 0.5 h View Scheme

: 1435-48-9
1,3-dichloro-4-fluorobenzene

: 704-10-9
2,4-dichloro-5-fluoroacetophenone

Conditions

Conditions	Yield
With hydrogenchloride; acetic anhydride; aluminium trichloride

: 95-50-1
1,2-dichloro-benzene

: 704-10-9
2,4-dichloro-5-fluoroacetophenone

Conditions

Conditions	Yield
Multi-step reaction with 4 steps 1.1: nitric acid; sulfuric acid / 2 h / 95 - 100 °C 2.1: potassium fluoride / 3 h / 140 - 150 °C 2.2: 7 h / 165 - 170 °C 3.1: chlorine / 8 h / 170 - 180 °C 4.1: aluminum (III) chloride / 110 °C View Scheme

: 99-54-7
3,4-dichloronitrobenzene

: 704-10-9
2,4-dichloro-5-fluoroacetophenone

Conditions

Conditions	Yield
Multi-step reaction with 3 steps 1.1: potassium fluoride / 3 h / 140 - 150 °C 1.2: 7 h / 165 - 170 °C 2.1: chlorine / 8 h / 170 - 180 °C 3.1: aluminum (III) chloride / 110 °C View Scheme

: 704-10-9
2,4-dichloro-5-fluoroacetophenone

: 86522-89-6
2,4-dichloro-5-fluoro-benzoic acid

Conditions

Conditions	Yield
With oxygen; nitric acid In water; acetic acid at 70℃; under 1500.15 Torr; for 0.15h; Catalytic behavior; Temperature; Time; Pressure; Flow reactor; Industrial scale; Green chemistry;	99.9%
With sodium hypochlorite In 1,4-dioxane	98%
With sodium hydroxide; chlorine In ethanol pH=10;	90%
With sodium percarbonate; potassium tert-butylate; sphingosylphosphorylcholine; meta-dinitrobenzene In tert-butyl alcohol at 80℃; for 5h;	35%
With sodium hydroxide; chlorine In ethanol for 6h; pH=8 - 10;

: 704-10-9
2,4-dichloro-5-fluoroacetophenone

: α,α,α,2,4-pentachloro-5-fluoroacetophenone

Conditions

Conditions	Yield
With chlorine In water	96%

: 704-10-9
2,4-dichloro-5-fluoroacetophenone

: 106809-14-7
2,4-dichloro-5-fluoro-3-nitro-benzoic acid

Conditions

Conditions	Yield
With sulfuric acid; nitric acid at 103 - 110℃; for 3h; Temperature;	91%
With sulfuric acid; nitric acid 1.) 55 deg C; 2.) 75 deg C, 3 h;	82%

2',4'-Dichloro-5'-fluoroacetophenone Chemical Properties

Synonyms:2',4'-Dichloro-5'-Fluoroacetophenone 2,4-Dichloro-5-Fluoroacetophenone;2',4'-Dichloro-5'-fluoroacetophenone 98%;2',4'-Dichloro-5'-fluoroacetophenone98% ; 2',4'-DICHLORO-5'-FLUOROACETOPHENONE;1-(2,4-DICHLORO-5-FLUORO-PHENYL)-ETHANONE;2',4'-DICHLORO-5'-FLUOROACETOPHENONE, 90;2,4-DICHLORO-5-FLUOROACETOPHENONE;1-(2,4-DICHLORO-5-FLUOROPHENYL)ETHAN-1-ONE;
The Molecular formula of 2,4-DICHLORO-5-FLUOROACETOPHENONE(704-10-9) : C₈H₅Cl₂FO
The Molecular Weight of 2,4-DICHLORO-5-FLUOROACETOPHENONE(704-10-9) : 207.03
Molecular Structure :

Melting point: 33-36 °C
Boiling point:167 °C(lit.)
Flash point: >230 °F
density: 1.425 g/mL at 25 °C(lit.)
refractive index: n20/D 1.546(lit.)

2',4'-Dichloro-5'-fluoroacetophenone Uses

2,4-DICHLORO-5-FLUOROACETOPHENONE(704-10-9) is used as pharmaceutical intermediates.

2',4'-Dichloro-5'-fluoroacetophenone Safety Profile

The Hazard Codes of 2,4-DICHLORO-5-FLUOROACETOPHENONE(704-10-9):

Xi,

F
Hazard Note: Flammable
The Risk Statements information of 2,4-DICHLORO-5-FLUOROACETOPHENONE(704-10-9):
36/37/38: Irritating to eyes, respiratory system and skin
The Safety Statements information of 2,4-DICHLORO-5-FLUOROACETOPHENONE(704-10-9):
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
37/39: Wear suitable gloves and eye/face protection
WGK Germany: 3

Post a RFQ

Cas No.:

Product Name:

Quantity:

Email:

Company name:

Valid Period:

Detailed Requirements:

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

What can I do for you?
Get Best Price

Get Best Price for 704-10-9