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2-Amino-5-methylthiazole

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Name

2-Amino-5-methylthiazole

EINECS 423-800-5
CAS No. 7305-71-7 Density 1.258 g/cm3
PSA 67.15000 LogP 1.61490
Solubility N/A Melting Point 93-98 °C(lit.)
Formula C4H6N2S Boiling Point 232.5 °C at 760 mmHg
Molecular Weight 114.171 Flash Point 94.4 °C
Transport Information UN 2811 Appearance white to light yellow crystal powder
Safety 60-61-29-26-37/39 Risk Codes 22-48/22-50/53-36/37/38
Molecular Structure Molecular Structure of 7305-71-7 (2-Amino-5-methylthiazole) Hazard Symbols HarmfulXn, DangerousN, IrritantXi
Synonyms

2-Thiazolamine, 5-methyl-;5-methylthiophen-2-amine;5-methyl-1,3-thiazol-2-amine;Thiazole, 2-amino-5-methyl-;2-Amino-5-inethylthiazole;

Article Data 23

2-Amino-5-methylthiazole Synthetic route

35511-15-0

methyl 2-methyl-4-hydroxy-2H-1,2-benzothiazine-3-carboxylate 1,1-dioxide

71125-38-7

meloxicam

7305-71-7

5-methyl-2-thiazol-2-amine

Conditions
ConditionsYield
With montmorillonite MK10 impregnated with ZnCl2 In o-xylene for 24h; Reagent/catalyst; Reflux; Green chemistry;90%
potassium thioacyanate

potassium thioacyanate

78-95-5

chloroacetone

7305-71-7

5-methyl-2-thiazol-2-amine

Conditions
ConditionsYield
With ammonium acetate on neutral alumina; silica gel In benzene at 80℃; for 6h;83%
137768-73-1

1-isothiocyanatopropa-1,2-diene

7305-71-7

5-methyl-2-thiazol-2-amine

Conditions
ConditionsYield
With ammonia59%
With ammonium hydroxide In tetrahydrofuran at 20℃; for 72h;59%
137768-73-1

1-isothiocyanatopropa-1,2-diene

A

7305-71-7

5-methyl-2-thiazol-2-amine

B

137768-80-0

(5,5'-dimethyl-[2,3'-bithiazolyl]-2'-ylidene)-(5-methylthiazol-2-yl)-amine

C

137768-81-1

5,5'-dimethyl-2'-imino-[2,3'-bithiazolyl]

Conditions
ConditionsYield
With ammonium hydroxide In tetrahydrofuran at 20℃;A 11%
B 50%
C n/a
71-23-8

propan-1-ol

7305-71-7

5-methyl-2-thiazol-2-amine

Conditions
ConditionsYield
With chlorine at 8 - 10℃; Behandeln des Reaktionsprodukts mit Thioharnstoff;
123-38-6

propionaldehyde

17356-08-0

thiourea

7305-71-7

5-methyl-2-thiazol-2-amine

Conditions
ConditionsYield
With sulfuryl dichloride
With chloroform; bromine
With chloroform; iodine
683-50-1

2-chloropropanal

17356-08-0

thiourea

7305-71-7

5-methyl-2-thiazol-2-amine

19967-57-8

bromo-2 propanal

17356-08-0

thiourea

7305-71-7

5-methyl-2-thiazol-2-amine

Conditions
ConditionsYield
Reaktion des Hydrats;
17356-08-0

thiourea

3400-55-3

2-bromopropionaldehyde diethyl acetal

7305-71-7

5-methyl-2-thiazol-2-amine

Conditions
ConditionsYield
With hydrogenchloride
17356-08-0

thiourea

2-bromo-propionaldehyde-hydrate

2-bromo-propionaldehyde-hydrate

7305-71-7

5-methyl-2-thiazol-2-amine

2-Amino-5-methylthiazole Chemical Properties

IUPAC Name: 5-Methyl-1,3-thiazol-2-amine 
Synonyms oF 2-Amino-5-methylthiazole (CAS NO.7305-71-7): 2-Thiazolamine, 5-methyl- ; 2-Amino-5-methylthiazole;akos bbs-00006638 ; 5-Methyl-2-thiazolamine ; 5-Methyl-thiazol-2-ylamine ; 5-Methyl-1,3-thiazol-2-amine ; Labotest-bb lt00080645 ; Buttpark 18\10-87 ;
CAS NO: 7305-71-7
Molecular Formula: C4H6N2S
Molecular Weight: 114.1688
Index of Refraction: 1.618
Surface Tension: 55.9 dyne/cm
Density oF 2-Amino-5-methylthiazole (CAS NO.7305-71-7): 1.258 g/cm3
Flash Point: 94.4 °C
Enthalpy of Vaporization: 46.92 kJ/mol
Boiling Point: 232.5 °C at 760 mmHg
Vapour Pressure: 0.0588 mmHg at 25°C
Molecular Structure:

2-Amino-5-methylthiazole Safety Profile

Hazard Codes oF 2-Amino-5-methylthiazole (CAS NO.7305-71-7): XnHarmful,NDangerous,XiIrritant   
Risk Statements: 22-48/22-50/53-36/37/38
R24: Toxic in contact with skin. R48/22: Harmful: danger of serious damage to health by prolonged exposure if swallowed. R50/53: Very toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment. R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 60-61-29-26-37/39
S60: This material and its container must be disposed of as hazardous waste. S61: Avoid release to the environment. Refer to special instructions / safety data sheets. S29: Do not empty into drains. S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S37/39: Wear suitable gloves and eye/face protection.
RIDADR: 2811
WGK Germany: 3
Hazard Note: Irritant/Keep Cold
HazardClass: 9
PackingGroup: III 

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