Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

2-Chloroquinoline

Related Products

Hot Products

Name

2-Chloroquinoline

EINECS 210-317-8
CAS No. 612-62-4 Density 1.27 g/cm3
PSA 12.89000 LogP 2.88820
Solubility Insoluble in water Melting Point 34-37 °C(lit.)
Formula C9H6ClN Boiling Point 267.3 °C at 760 mmHg
Molecular Weight 163.606 Flash Point 141.2 °C
Transport Information N/A Appearance white to yellowish crystals, powder, chunks
Safety 26-36-37/39 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 612-62-4 (2-Chloroquinoline) Hazard Symbols IrritantXi
Synonyms

NSC 6163;

Article Data 48

2-Chloroquinoline Chemical Properties

IUPAC Name: 2-chloroquinoline 
Synonyms of of 2-Chloroquinoline (CAS NO.612-62-4): 5-20-07-00312 (Beilstein Handbook Reference) ; AI3-08909 ; BRN 0112561 ; CCRIS 3977 ; EINECS 210-317-8 ; NSC 6163 ; Quinoline, 2-chloro-
CAS NO: 612-62-4
Molecular Formula of 2-Chloroquinoline (CAS NO.612-62-4): C9H6ClN
Molecular Weight: 163.6036 
H bond acceptors: 1
H bond donors: 0
Freely Rotating Bonds: 0
Polar Surface Area: 12.89 Å2
Index of Refraction: 1.652
Molar Refractivity: 47.08 cm3
Molar Volume: 128.7 cm3 
Surface Tension: 49.3 dyne/cm
Density: 1.27 g/cm3
Flash Point: 141.2 °C
Enthalpy of Vaporization: 48.49 kJ/mol
Boiling Point: 267.3 °C at 760 mmHg
Vapour Pressure: 0.0136 mmHg at 25°C
Molecular Structure:

2-Chloroquinoline Safety Profile

Hazard Codes of 2-Chloroquinoline (CAS NO.612-62-4): IrritantXi
Risk Statements: 36/37/38 
R36/37/38: Irritating to eyes, respiratory system and skin.
Safety Statements: 26-36-37/39 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36: Wear suitable protective clothing. S37/39: Wear suitable gloves and eye/face protection.
WGK Germany :3
RTECS: VB2320000
F: 8 

2-Chloroquinoline Specification

The effects of prolonged p.o. administration of quinoline or 2-Chloroquinoline (CAS NO.612-62-4) on rat liver were examined histologically. Hepatocellular carcinomas and hemangioendotheliomas were observed in the livers of rats fed a basal diet containing 0.05, 0.10, or 0.25% quinoline for about 16 to 40 weeks. However, no neoplastic changes were seen in the livers of rats fed a basal diet containing 0.05, 0.10, or 0.25% 2-chloroquinoline for 40 weeks. In groups that received low concentrations of quinoline, the incidences of hepatocellular carcinomas were higher and the incidences of hemangioendotheliomas were lower than in the group that received a high concentration of quinoline.

The liver tumors induced by quinoline were classified histologically as hemangioendotheliomas or hemangiosarcomas and trabecular hepatocellular carcinomas. Typical nodular hyperplasias were occasionally seen in the livers of rats treated with quinoline. 2-Chloroquinoline (CAS NO.612-62-4) did not induce any nodular hyperplasia or other neoplastic changes, but it caused diffuse fatty changes of parenchymal cells. Oval cell infiltration and bile duct proliferation were slight or moderate. Cirrhotic changes were rare in the livers of rats treated with either quinoline or 2-chloroquinoline.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 612-62-4