Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

2-Fluoroadenosine

Related Products

Hot Products

Name

2-Fluoroadenosine

EINECS 633-923-8
CAS No. 146-78-1 Density 2.176 g/cm3
PSA 139.54000 LogP -1.25970
Solubility N/A Melting Point 240 °C
Formula C10H12FN5O4 Boiling Point 747.303 °C at 760 mmHg
Molecular Weight 285.235 Flash Point 405.755 °C
Transport Information N/A Appearance white powder
Safety 26 Risk Codes 22-36/37/38
Molecular Structure Molecular Structure of 146-78-1 (2-Fluoroadenosine) Hazard Symbols HarmfulXn
Synonyms

6-Amino-2-fluoro-9-beta-D-ribofuranosylpurine;NSC 30605;Purine, 6-amino-2-fluoro-9-beta-D-ribofuranosyl-;

Article Data 48

2-Fluoroadenosine Specification

The 2-Fluoroadenosine, with the CAS registry number 146-78-1, is also known as 6-Amino-2-fluoro-9-beta-D-ribofuranosylpurine. It belongs to the product categories of Miscellaneous Biochemicals; API intermediates; Biochemistry; Nucleosides and their analogs; Nucleosides, Nucleotides & Related Reagents; Nucleosides; Oligonucleotide Synthesis; Specialty Synthesis. This chemical's molecular formula is C10H12FN5O4 and molecular weight is 285.23. What's more, its IUPAC name is (2R,3R,4S,5R)-2-(6-amino-2-fluoropurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol. Its classification code is Drug / Therapeutic Agent. This chemical is stable at common pressure and temperature, and it should be sealed and stored in a cool and dry place.

Physical properties of 2-Fluoroadenosine are: (1)ACD/LogP: -0.8; (2)# of Rule of 5 Violations: 1; (3)ACD/LogD (pH 5.5): -0.80; (4)ACD/LogD (pH 7.4): -0.80; (5)ACD/BCF (pH 5.5): 1.00; (6)ACD/BCF (pH 7.4): 1.00; (7)ACD/KOC (pH 5.5): 8.75; (8)ACD/KOC (pH 7.4): 8.75; (9)#H bond acceptors: 9; (10)#H bond donors: 5; (11)#Freely Rotating Bonds: 5; (12)Polar Surface Area: 139.54 Å2; (13)Index of Refraction: 1.876; (14)Molar Refractivity: 59.829 cm3; (15)Molar Volume: 131.068 cm3; (16)Polarizability: 23.718×10-24cm3; (17)Surface Tension: 98.67 dyne/cm; (18)Density: 2.176 g/cm3; (19)Flash Point: 405.755 °C; (20)Enthalpy of Vaporization: 114.324 kJ/mol; (21)Boiling Point: 747.303 °C at 760 mmHg; (22)Vapour Pressure: 0 mmHg at 25°C.

When you are using this chemical, please be cautious about it as the following:
This chemical is harmful if swallowed. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice.

You can still convert the following datas into molecular structure:
(1)SMILES: Fc1nc(c2ncn(c2n1)[C@@H]3O[C@@H]([C@@H](O)[C@H]3O)CO)N
(2)Std. InChI: InChI=1S/C10H12FN5O4/c11-10-14-7(12)4-8(15-10)16(2-13-4)9-6(19)5(18)3(1-17)20-9/h2-3,5-6,9,17-19H,1H2,(H2,12,14,15)/t3-,5-,6-,9-/m1/s1
(3)Std. InChIKey: HBUBKKRHXORPQB-UUOKFMHZSA-N  

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD10 unreported 1000ug/kg (1mg/kg)   Progress in Medical Chemistry. Vol. 7, Pg. 69, 1970.
mouse LD50 intraperitoneal 27040ug/kg (27.04mg/kg)   National Cancer Institute Screening Program Data Summary, Developmental Therapeutics Program. Vol. JAN1986.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 146-78-1