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  • EINECS203-644-2
  • CAS No. 109-07-9
  • Density0.845 g/cm3
  • PSA24.06000
  • LogP0.22530
  • Solubility78 g/100 mL (25 °C) in water
  • Melting Point61-63 °C(lit.)
  • FormulaC5H12N2
  • Boiling Point153.2 °C at 760 mmHg
  • Molecular Weight100.164
  • Flash Point45.1 °C
  • Transport InformationUN 1325 4.1/PG 2
  • Appearancewhite to yellow crystalline powder and chunks
  • Safety16-26-36/37/39-36
  • Risk Codes11-36/37/38
  • Molecular Structure
    Molecular Structure of 109-07-9 (2-Methylpiperazine)
  • Hazard SymbolsFlammableF,IrritantXi
  • SynonymsFlammableF,IrritantXi
  • Article Data34

2-METHYLPIPERAZINE Chemical Properties

MF: C5H12N2
MW: 100.16
mp of 2-METHYLPIPERAZINE (109-07-9): 61-63 °C(lit.)
bp of 2-METHYLPIPERAZINE (109-07-9): 155 °C 763 mm Hg(lit.)
density: 0.817 g/cm3
Fp of 2-METHYLPIPERAZINE (109-07-9): 149 °F
storage temp.: Flammables area
Water Solubility: 78 g/100 mL (25 oC)
PHYSICAL STATE: white crystal


2-METHYLPIPERAZINE (109-07-9) is used as pharmaceutical intermediates, synthetic Lomefloxacin raw materials. It is used in the synthesis of drugs like quinolone class antibiotics, agrochemicals and other chemical compounds.

2-METHYLPIPERAZINE Toxicity Data With Reference


orl-rat LD50:2030 mg/kg

   JACTDZ    Journal of the American College of Toxicology. 1 (1990),58.

2-METHYLPIPERAZINE Consensus Reports

Reported in EPA TSCA Inventory.


Hazard Codes: F,Xi (Highly Flammable; Irritant)
Risk Statements: 11-36/37/38 (Highly Flammable; Irritating to eyes, respiratory system and skin)
Safety Statements: 16-26-36/37/39-36 (Keep away from sources of ignition - No smoking; In case of contact with eyes, rinse immediately with plenty of water and seek medical advice; Wear suitable protective clothing, gloves and eye/face protection; Wear suitable protective clothing)
RIDADR: UN 1325 4.1/PG 2
WGK Germany: 2
RTECS: TM1225020
F: 10 (Keep under argon)
HazardClass: 4.1
PackingGroup: III
Moderately toxic by ingestion. When heated to decomposition it emits toxic vapors of NOx.

2-METHYLPIPERAZINE Standards and Recommendations

PURITY: 99.0% min
WATER: 0.5% max


Storage: Store away from water/moisture. Do not store together with oxidizing and acidic materials. Keep container tightly sealed. Store in cool, dry conditions in well sealed containers.
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