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3,3-Dimethylglutarimide

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3,3-Dimethylglutarimide

EINECS 214-373-4
CAS No. 1123-40-6 Density 1.054 g/cm3
PSA 46.17000 LogP 0.77800
Solubility Soluble in water. Melting Point 144-146 °C(lit.)
Formula C7H11NO2 Boiling Point 268 °C at 760 mmHg
Molecular Weight 141.17 Flash Point 125.3 °C
Transport Information N/A Appearance white to white-grey crystalline powder
Safety 26-36/37-22 Risk Codes 22-36/37/38-43
Molecular Structure Molecular Structure of 1123-40-6 (3,3-DIMETHYLGLUTARIMIDE) Hazard Symbols HarmfulXn,IrritantXi
Synonyms

Glutarimide,3,3-dimethyl- (6CI,7CI,8CI);3,3-Dimethylglutarimide;4,4-Dimethyl-2,6-piperidinedione;4,4-Dimethylglutarimide;NSC 58194;NSC99206;b,b-Dimethylglutarimide;

Article Data 15

3,3-Dimethylglutarimide Specification

The 3,3-Dimethylglutarimide is an organic compound with the formula C7H11NO2. The systematic name of this chemical is 4,4-dimethylpiperidine-2,6-dione. With the CAS registry number 1123-40-6, it is also named as 2,6-piperidinedione, 4,4-dimethyl-. The product's categories are Building Blocks; Heterocyclic Building Blocks; Piperidines. Besides, it is a white to white-grey crystalline powder, which should be stored in a closed cool and dry place.

Physical properties about 3,3-Dimethylglutarimide are: (1)ACD/LogP: 0.99; (2)ACD/LogD (pH 5.5): 0.99; (3)ACD/LogD (pH 7.4): 0.99; (4)ACD/BCF (pH 5.5): 3.35; (5)ACD/BCF (pH 7.4): 3.35; (6)ACD/KOC (pH 5.5): 82.73; (7)ACD/KOC (pH 7.4): 82.73; (8)#H bond acceptors: 3; (9)#H bond donors: 1; (10)Polar Surface Area: 37.38 Å2; (11)Index of Refraction: 1.45; (12)Molar Refractivity: 35.98 cm3; (13)Molar Volume: 133.8 cm3; (14)Polarizability: 14.26×10-24cm3; (15)Surface Tension: 30.8 dyne/cm; (16)Density: 1.054 g/cm3; (17)Flash Point: 125.3 °C; (18)Enthalpy of Vaporization: 50.6 kJ/mol; (19)Boiling Point: 268 °C at 760 mmHg; (20)Vapour Pressure: 0.0079 mmHg at 25°C.

Uses of 3,3-Dimethylglutarimide: it can be used to produce N-chloro-3,3-dimethylglutarimide at temperature of 0 °C. It will need reagent NaOH, Cl2 and solvent H2O with reaction time of 30 min. The yield is about 85%.

When you are using this chemical, please be cautious about it as the following:
It is harmful if swallowed and may cause sensitisation by skin contact. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Besides, this chemical is irritating to eyes, respiratory system and skin. When you are using it, wear suitable protective clothing and gloves and do not breathe dust.

You can still convert the following datas into molecular structure:
(1)SMILES: O=C1NC(=O)CC(C)(C)C1
(2)InChI: InChI=1/C7H11NO2/c1-7(2)3-5(9)8-6(10)4-7/h3-4H2,1-2H3,(H,8,9,10)
(3)InChIKey: YUJCWMGBRDBPDL-UHFFFAOYAL
(4)Std. InChI: InChI=1S/C7H11NO2/c1-7(2)3-5(9)8-6(10)4-7/h3-4H2,1-2H3,(H,8,9,10)
(5)Std. InChIKey: YUJCWMGBRDBPDL-UHFFFAOYSA-N

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intraperitoneal 152mg/kg (152mg/kg) BEHAVIORAL: CONVULSIONS OR EFFECT ON SEIZURE THRESHOLD Farmakologiya i Toksikologiya Vol. 27, Pg. 278, 1964.

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