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3-Nitro-L-tyrosine

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Name

3-Nitro-L-tyrosine

EINECS 210-688-6
CAS No. 621-44-3 Density 1.531 g/cm3
PSA 129.37000 LogP 1.47830
Solubility insoluble in water Melting Point 233-235 °C (dec.)(lit.)
Formula C9H10N2O5 Boiling Point 431.6 °C at 760 mmHg
Molecular Weight 226.189 Flash Point 214.8 °C
Transport Information N/A Appearance ochre-yellow to yellow-green powder
Safety 24/25-37/39-26-36 Risk Codes 36/37/38
Molecular Structure Molecular Structure of 621-44-3 (3-Nitro-L-tyrosine) Hazard Symbols IrritantXi
Synonyms

Tyrosine,3-nitro-, L- (8CI);3-Nitro-L-tyrosine;NSC 37413;H-Tyr(3-NO2)-OH;

Article Data 32

3-Nitro-L-tyrosine Chemical Properties

IUPAC Name: 2-amino-3-(4-hydroxy-3-nitrophenyl)propanoic acid
The MF of 3-Nitro-L-tyrosine(621-44-3): C9H10N2O5
The MW of 3-Nitro-L-tyrosine(621-44-3): 226.19
EINECS: 210-688-6
mp: 233-235 °C (dec.)(lit.)
Density: 1.531 g/cm3 
Flash Point: 214.8 °C 
Boiling Point: 431.6 °C at 760 mmHg 
Index of Refraction: 1.65 
alpha: 4 °(c=1, 1N HCl)
storage temp.: -15°C
form: crystalline
color: yellow to green
Water Solubility: insoluble
Categories: Pharmaceutical Raw Materials;Amino Acids;Tyrosine [Tyr, Y];Unusual Amino Acids;Peptide Synthesis;Tyrosine Derivatives;Unnatural Amino Acid Derivatives;Oxidative Stress Proteins and ReagentsPeptide Synthesis;Cell Stress;Nitric Oxide and Cell Stress
Synonyms: M-NITRO-L-TYROSINE;NITROTYROSINE;H-TYR(M-NO2)-OH;H-TYR(3-NO2)-OH;H-4-HYDROXY-3-NITRO-PHE-OH;H-3-NITRO-L-TYROSINE;H-3-NITRO-TYR-OH;
The Structure of 3-Nitro-L-tyrosine(621-44-3):

3-Nitro-L-tyrosine Safety Profile

Hazard Codes: Xi
Risk Statements: 36/37/38
36/37/38:  Irritating to eyes, respiratory system and skin 
Safety Statements: 24/25-37/39-26-36
24/25:  Avoid contact with skin and eyes 
37/39:  Wear suitable gloves and eye/face protection 
26:  In case of contact with eyes, rinse immediately with plenty of water and seek medical advice 
36:  Wear suitable protective clothing 
WGK Germany: 3

3-Nitro-L-tyrosine Specification

1. First Aid Measures
Ingestion:
Never give anything by mouth to an unconscious person. Get medical aid. Do NOT induce vomiting. If conscious and alert, rinse mouth and drink 2-4 cupfuls of milk or water.
Inhalation:
Remove from exposure to fresh air immediately. If not breathing, give artificial respiration. If breathing is difficult, give oxygen. Get medical aid.
Skin:
Get medical aid. Flush skin with plenty of soap and water for at least 15 minutes while removing contaminated clothing and shoes. Wash clothing before reuse.
Eyes:
Flush eyes with plenty of water for at least 15 minutes, occasionally lifting the upper and lower eyelids. Get medical aid.
2. Handling and Storage
Storage:
Keep container closed when not in use. Store in a tightly closed container. Store in a cool, dry, well-ventilated area away from incompatible substances.
Handling:
Wash thoroughly after handling. Remove contaminated clothing and wash before reuse. Use with adequate ventilation. Minimize dust generation and accumulation. Avoid contact with eyes, skin, and clothing. Keep container tightly closed. Avoid ingestion and inhalation.
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