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4-(4-Chlorophenyl)-4-hydroxypiperidine

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Name

4-(4-Chlorophenyl)-4-hydroxypiperidine

EINECS 254-479-8
CAS No. 39512-49-7 Density 1.216 g/cm3
PSA 32.26000 LogP 2.23980
Solubility 340 mg/L (20 °C ) in water Melting Point 137-140 °C(lit.)
Formula C11H14ClNO Boiling Point 344.5 °C at 760 mmHg
Molecular Weight 211.691 Flash Point 162.1 °C
Transport Information N/A Appearance white to creamy-white crystalline powder
Safety 26-37/39-36 Risk Codes 36/37/38-22
Molecular Structure Molecular Structure of 39512-49-7 (4-(4-Chlorophenyl)piperidin-4-ol) Hazard Symbols HarmfulXn, IrritantXi
Synonyms

4-Piperidinol, 4-(4-chlorophenyl)-;4-(p-Chlorophenyl)piperidin-4-ol;Haloperidol metabolite I;4-(4'-Chlorophenyl)-4-piperidinol;

Article Data 13

4-(4-Chlorophenyl)-4-hydroxypiperidine Chemical Properties

Molecular structure of 4-(4'-Chlorophenyl)-4-piperidinol (CAS NO.39512-49-7) is:

Product Name: 4-(4'-Chlorophenyl)-4-piperidinol
CAS Registry Number: 39512-49-7
IUPAC Name: 4-(4-Chlorophenyl)piperidin-4-ol
Molecular Weight: 211.68796 [g/mol]
Molecular Formula: C11H14ClNO
XLogP3-AA: 1.6
H-Bond Donor: 2
H-Bond Acceptor: 2 
EINECS: 254-479-8
Melting Point: 137-140 °C(lit.)
Water Solubility: 340 mg/L (20 °C ) 
Surface Tension: 46 dyne/cm
Density: 1.216 g/cm3
Flash Point: 162.1 °C
Enthalpy of Vaporization: 62.1 kJ/mol
Boiling Point: 344.5 °C at 760 mmHg
Vapour Pressure: 2.5E-05 mmHg at 25°C
Product Categories: Pharmaceutical intermediateS; Building blocks; Piperazine

4-(4-Chlorophenyl)-4-hydroxypiperidine Uses

 4-(4'-Chlorophenyl)-4-piperidinol (CAS NO.39512-49-7) is used as an intermediate for the synthesis of pharmaceuticals such as haloperidol (neuroleptic drug used to treat patients with psychotic illnesses, extreme agitation, or Tourette's syndrome) and loperamide (an opioid that slows down movements of the gut and is used to treat acute diarrhoea).

4-(4-Chlorophenyl)-4-hydroxypiperidine Safety Profile

Safty information about 4-(4'-Chlorophenyl)-4-piperidinol (CAS NO.39512-49-7) is:
Hazard Codes: IrritantXi,Xn
Risk Statements: 36/37/38-22 
R36/37/38:Irritating to eyes, respiratory system and skin. 
R22:Harmful if swallowed.
Safety Statements: 26-37/39-36 
S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. 
S37/39:Wear suitable gloves and eye/face protection. 
S36:Wear suitable protective clothing.
WGK Germany: 3
HazardClass: IRRITANT
HS Code: 29333999

4-(4-Chlorophenyl)-4-hydroxypiperidine Specification

 4-(4'-Chlorophenyl)-4-piperidinol , its cas register number is 39512-49-7. It also can be called 4-(p-Chlorophenyl)piperidin-4-ol ; 4-Piperidinol, 4-(4-chlorophenyl)- ; Haloperidol metabolite I . It is a white to creamy-white crystalline powder.

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