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Cas Database |
| Name |
4-AMINOANTIPYRINE |
EINECS | 201-452-3 |
| CAS No. | 83-07-8 | Density | 1.207 g/cm3 |
| PSA | 52.95000 | LogP | 1.64780 |
| Solubility | water: 0.1 g/mL, clear | Melting Point |
105-110 °C(lit.) |
| Formula | C11H13N3O | Boiling Point | 309 °C at 760 mmHg |
| Molecular Weight | 203.244 | Flash Point | 140.7 °C |
| Transport Information | N/A | Appearance | Amber crystalline powder |
| Safety | 26-36-36/37/39 | Risk Codes | 22-36/37/38-20/21/22 |
| Molecular Structure |
|
Hazard Symbols |
 Xn
|
| Synonyms |
Antipyrine,4-amino- (8CI);1,2-Dihydro-1,5-dimethyl-2-phenyl-4-amino-3H-pyrazol-3-one;4-AAP;4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one;4-Amino-1,5-dimethyl-2-phenylpyrazolin-3-one;4-Amino-2,3-dimethyl-1-phenyl-5-pyrazolone;Aminoantipyrine;Ampyrone;NSC 60242;1-Phenyl-2,3-dimethyl-4-aminopyrazol-5-one; |
Article Data | 37 |
4-AMINOANTIPYRINE Chemical Properties
IUPAC Name: 4-Aminoantipyrine
The MF of 4-Aminoantipyrine (83-07-8) is C11H13N3O.
The MW of 4-Aminoantipyrine (83-07-8) is 203.24.
Synonyms of 4-Aminoantipyrine (83-07-8): 4-Amino-1,2-dihydro-1,5-dimethyl-2-phenyl-3H-pyrazol-3-one ; 4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-3H-pyrazol-3-one ; 4-Amino-1,5-dimethyl-2-phenyl-1,2-dihydro-pyrazol-3-one
Product Categories: Drug bulk;Pyridines, Pyrimidines, Purines and Pteredines
Form: amber crystalline powder
Index of Refraction: 1.606
EINECS: 201-452-3
Density: 1.207 g/ml
Flash Point: 140.7 °C
Boiling Point: 309 °C
Melting Point: 107-109 °C
Storage temp: Store at RT
Water Solubility: 500 g/L (20 ºC)
Merck: 14,591
BRN: 181635
Stability: Stable
4-AMINOANTIPYRINE Uses
4-Aminoantipyrine (83-07-8) is pharmaceutical intermediates analgin used to test alcohol and amines, phenols measured air and water.
4-AMINOANTIPYRINE Toxicity Data With Reference
| 1. | mmo-sat 5 µmol/plate | MUREAV Mutation Research. 206 (1988),317. | ||
| 2. | dnr-esc 312 µg/well | MUREAV Mutation Research. 133 (1984),161. | ||
| 3. | orl-rat LD50:1700 mg/kg | BCFAAI Bollettino Chimico Farmaceutico. 117 (1978),638. | ||
| 4. | ipr-rat LD50:1200 mg/kg | JPETAB Journal of Pharmacology and Experimental Therapeutics. 99 (1950),171. | ||
| 5. | orl-mus LD50:800 mg/kg | CCCCAK Collection of Czechoslovak Chemical Communications. 47 (1982),636. | ||
| 6. | ipr-mus LD50:270 mg/kg | ARZNAD Arzneimittel-Forschung. Drug Research. 10 (1960),820. |
4-AMINOANTIPYRINE Consensus Reports
Reported in EPA TSCA Inventory.
4-AMINOANTIPYRINE Safety Profile
Poison by intraperitoneal route. Moderately toxic by ingestion. Mutation data reported. When heated to decomposition it emits acrid smoke and irritating vapors.
Safety information of 4-Aminoantipyrine (83-07-8):
Hazard Codes 
Xn
Risk Statements
36/37/38 Irritating to eyes, respiratory system and skin
20/21/22 Harmful by inhalation, in contact with skin and if swallowed
Safety Statements
26 In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36/37/39 Wear suitable protective clothing, gloves and eye/face protection
WGK Germany 3
RTECS CD2480000
F 8-9-23
Hazard Note Harmful
HS Code 29331190
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