The 4-Aminopyridine, with the CAS registry number 504-24-5, is also known as Dalfampridine. 4-Aminopyridine is an organic compound with the chemical formula C₅H₄N–NH₂. It belongs to the product categories of Pyridine; Organics; Amines; Pyridines; Pyridines derivates; Heterocyclic Compounds; Alphabetical Listings; Stable Isotopes; Potassium channel; Ion Channels. Its EINECS number is 207-987-9 and molecular weight is 94.11. What's more, its systematic name is pyridin-4-amine. It should be sealed and stored in a dry place. Moreover, it should be protected from light. It is one of the potassium channel blockers, with secondary effect on calcium currents, which is used mainly as a research tool and to characterize channel subtypes. It is used in organic synthesis.

Physical properties of 4-Aminopyridine are: (1)ACD/LogP: 0.26; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -2.22; (4)ACD/LogD (pH 7.4): -1.51; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 2; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 1; (12)Polar Surface Area: 16.13 Å²; (13)Index of Refraction: 1.587; (14)Molar Refractivity: 28.58 cm³; (15)Molar Volume: 84.9 cm³; (16)Polarizability: 11.33×10^-24cm³; (17)Surface Tension: 51.2 dyne/cm; (18)Density: 1.107 g/cm³; (19)Flash Point: 131.8 °C; (20)Enthalpy of Vaporization: 49.27 kJ/mol; (21)Boiling Point: 255.2 °C at 760 mmHg; (22)Vapour Pressure: 0.0165 mmHg at 25°C.

Preparation of  4-Aminopyridine: this chemical can be prepared by 4-nitro-pyridine-1-oxide at the ambient temperature. This reaction will need reagents TiCl₄, SnCl₂ and solvent tetrahydrofuran with the reaction time of 30 min. The yield is about 95%.

Uses of 4-Aminopyridine: it can be used to produce N-pyridin-4-yl-benzamide at the temperature of 60 °C. It will need reagent triethylamine and solvent 1,2-dichloro-ethane with the reaction time of 3 hours. The yield is about 73%.

When you are using this chemical, please be cautious about it as the following:
This chemical is toxic by inhalation, in contact with skin and if swallowed. It is toxic to aquatic organisms as it may cause long-term adverse effects in the aquatic environment. It is irritating to eyes, respiratory system and skin. In case of contact with eyes, you should rinse immediately with plenty of water and seek medical advice. When using it, you need wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, you must seek medical advice immediately (show the label where possible). This material and its container must be disposed of as hazardous waste. You should avoid releasing it to the environment just refering to special instructions/safety data sheet.

You can still convert the following datas into molecular structure:
(1)SMILES: n1ccc(N)cc1
(2)Std. InChI: InChI=1S/C5H6N2/c6-5-1-3-7-4-2-5/h1-4H,(H2,6,7)
(3)Std. InChIKey: NUKYPUAOHBNCPY-UHFFFAOYSA-N

The toxicity data is as follows: