Welcome to LookChem.com Sign In|Join Free
  • or
Home > Products >  > 

7-Methyltryptamine

Related Products

Hot Products

Name

7-Methyltryptamine

EINECS 238-498-9
CAS No. 14490-05-2 Density 1.126 g/cm3
PSA 41.81000 LogP 2.67780
Solubility Soluble in ethanol (5% w/v) Melting Point 123-130 °C
Formula C11H14N2 Boiling Point 349.2 °C at 760 mmHg
Molecular Weight 174.246 Flash Point 192 °C
Transport Information N/A Appearance Off-white crystalline powder
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 14490-05-2 (7-Methyltryptamine) Hazard Symbols N/A
Synonyms

Indole,3-(2-aminoethyl)-7-methyl- (6CI,7CI,8CI);7-Methyltryptamine;NSC 91540;

Article Data 11

7-Methyltryptamine Synthetic route

(E)-7-methyl-3-(2-nitrovinyl)-1H-indole

14490-05-2

7-methyltryptamine

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran at 0 - 20℃; Inert atmosphere;99%
With lithium aluminium tetrahydride In tetrahydrofuran
858232-97-0

2-(7-methyl-1H-indol-3-yl)acetonitrile

14490-05-2

7-methyltryptamine

Conditions
ConditionsYield
With lithium aluminium tetrahydride
14517-83-0

3-(2-amino-ethyl)-7-methyl-indole-2-carboxylic acid

14490-05-2

7-methyltryptamine

Conditions
ConditionsYield
With hydrogenchloride
6346-09-4

4-aminobutyrylaldehyde diethylacetal

529-27-1

2-methylphenylhydrazine

14490-05-2

7-methyltryptamine

Conditions
ConditionsYield
With zinc(II) chloride
933-67-5

7-methyl-1H-indole

14490-05-2

7-methyltryptamine

Conditions
ConditionsYield
Multi-step reaction with 3 steps
1: POCl3
2: AcOH
3: LiAH4 / tetrahydrofuran
View Scheme
Multi-step reaction with 3 steps
1.1: trichlorophosphate / 1.5 h / Cooling with ice
1.2: 20 °C / Cooling with ice
1.3: 1 h / 105 °C
2.1: ammonium acetate / Reflux
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 3 steps
1: diethyl ether / 18 h / 40 °C
2: ammonia / 1,4-dioxane / 20 °C
3: lithium aluminium tetrahydride / tetrahydrofuran / 18 h / Reflux
View Scheme
Multi-step reaction with 3 steps
1.1: trichlorophosphate / 0.25 h / 0 °C / Inert atmosphere
1.2: 3.25 h / 0 - 20 °C / Inert atmosphere
1.3: 0.08 h / Reflux
2.1: ammonium acetate / 1.5 h / Reflux; Inert atmosphere
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 36 h / 0 - 20 °C / Inert atmosphere
View Scheme
4771-50-0

7-methyl-1H-indole-3-carbaldehyde

14490-05-2

7-methyltryptamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: AcOH
2: LiAH4 / tetrahydrofuran
View Scheme
Multi-step reaction with 2 steps
1: ammonium acetate / Reflux
2: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: ammonium acetate / 2 h / Reflux
2: lithium aluminium tetrahydride / tetrahydrofuran / 36 h / 0 - 20 °C / Inert atmosphere
View Scheme
Multi-step reaction with 2 steps
1: ammonium acetate / 1.5 h / Reflux; Inert atmosphere
2: lithium aluminium tetrahydride / tetrahydrofuran / 36 h / 0 - 20 °C / Inert atmosphere
View Scheme
14490-04-1

8-methyl-2,3,4,9-tetrahydro-β-carbolin-1-one

14490-05-2

7-methyltryptamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: aq.-ethanolic KOH
2: aqueous HCl
View Scheme
88-72-2

1-methyl-2-nitrobenzene

14490-05-2

7-methyltryptamine

Conditions
ConditionsYield
Multi-step reaction with 4 steps
1.1: tetrahydrofuran / 1 h / -40 °C / Inert atmosphere
2.1: trichlorophosphate / 1.5 h / Cooling with ice
2.2: 20 °C / Cooling with ice
2.3: 1 h / 105 °C
3.1: ammonium acetate / Reflux
4.1: lithium aluminium tetrahydride / tetrahydrofuran / 0 - 20 °C / Inert atmosphere
View Scheme
59022-69-4

2-(7-methyl-1H-indol-3-yl)-2-oxoacetyl chloride

14490-05-2

7-methyltryptamine

Conditions
ConditionsYield
Multi-step reaction with 2 steps
1: ammonia / 1,4-dioxane / 20 °C
2: lithium aluminium tetrahydride / tetrahydrofuran / 18 h / Reflux
View Scheme

C11H10N2O2

14490-05-2

7-methyltryptamine

Conditions
ConditionsYield
With lithium aluminium tetrahydride In tetrahydrofuran for 18h; Reflux;

7-Methyltryptamine Specification

The 7-Methyltryptamine, with the cas registry number 14490-05-2 and EINECS registry number 238-498-9, has the systematic name of 2-(7-methyl-1H-indol-3-yl)ethanamine. The molecular formula of the chemical is C11H14N2. The chemical belongs to the following product categories: Tryptamines; Heterocyclic Compounds; Building Blocks; Heterocyclic Building Blocks; Indoles. What's meore, it should be stored at the temperature of -20°C.

The characteristics of this chemical are as followings: (1)ACD/LogP: 1.84; (2)# of Rule of 5 Violations: 0; (3)ACD/LogD (pH 5.5): -1.25; (4)ACD/LogD (pH 7.4): -0.77; (5)ACD/BCF (pH 5.5): 1; (6)ACD/BCF (pH 7.4): 1; (7)ACD/KOC (pH 5.5): 1; (8)ACD/KOC (pH 7.4): 1; (9)#H bond acceptors: 2; (10)#H bond donors: 3; (11)#Freely Rotating Bonds: 3; (12)Polar Surface Area: 8.17 Å2; (13)Index of Refraction: 1.65; (14)Molar Refractivity: 56.43 cm3; (15)Molar Volume: 154.6 cm3; (16)Polarizability: 22.37×10-24cm3; (17)Surface Tension: 51.3 dyne/cm; (18)Density: 1.126 g/cm3; (19)Flash Point: 192 °C; (20)Enthalpy of Vaporization: 59.37 kJ/mol; (21)Boiling Point: 349.2 °C at 760 mmHg; (22)Vapour Pressure: 4.77E-05 mmHg at 25°C.

Addtionally, the following datas could be converted into the molecular structure:
(1)SMILES: c1ccc(c2c1c(cn2)CCN)C
(2)InChI: InChI=1/C11H14N2/c1-8-3-2-4-10-9(5-6-12)7-13-11(8)10/h2-4,7,13H,5-6,12H2,1H3
(3)InChIKey: SGGBZKQTWMKXHD-UHFFFAOYAH

The toxicity data is as follows:

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
mouse LD50 intravenous 63mg/kg (63mg/kg)   U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. Vol. NX#12400,

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 14490-05-2