- ARSANILIC ACID, MONOSODIUM SALT
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| Name |
ARSANILIC ACID, MONOSODIUM SALT |
EINECS | N/A |
| CAS No. | 127-85-5 | Density | g/cm3 |
| PSA | 89.21000 | LogP | 0.28740 |
| Solubility | Soluble in water | Melting Point |
300°C (dec.) |
| Formula | C6H8 As N O3 . Na | Boiling Point | 528.5°Cat760mmHg |
| Molecular Weight | 239.038 | Flash Point | 273.4°C |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by subcutaneous route. Can cause blindness. When heated to decomposition it emits very toxic fumes of As and NOx. | Risk Codes | 26/27/28 |
| Molecular Structure |
|
Hazard Symbols | Highly toxic by ingestion and inhalation, may cause blindness. |
| Synonyms |
Arsanilicacid, monosodium salt (8CI); Arsonic acid, (4-aminophenyl)-, monosodium salt(9CI); Arsamin; Arsinosolvin; Atoxyl; Atoxyl (pharmaceutical); Nuarsol; PigletPro-Gen V; Pro-Gen Sodium; Protoxyl; Soamin; Sodium aminarsonate; Sodiumanilarsonate; Sodium arsanilate; Sodium p-aminobenzenearsonate; Sodiump-aminophenylarsonate; Sodium p-aminophenylarsonate; Sodium p-arsanilate;Sonate; Trypoxyl |
ARSANILIC ACID, MONOSODIUM SALT Synthetic route
| Conditions | Yield |
|---|---|
| at 150℃; |
- 6320-96-3
3-bromopropanamide
- 127-85-5
p-arsanilic acid monosodium salt
- 787494-77-3
[4-(2-carbamoyl-ethylamino)-phenyl]-arsonic acid
- 5180-74-5
4-ethoxycarbonylamino-benzoyl chloride
- 127-85-5
p-arsanilic acid monosodium salt
- 861301-81-7
[4-(4-ethoxycarbonylamino-benzoylamino)-phenyl]-arsonic acid
| Conditions | Yield |
|---|---|
| With diethyl ether; sodium acetate | |
| With diethyl ether; alkaline sodium acetate |
- 17640-79-8
2-chloro-N-(4-hydroxy-3-methoxyphenyl)acetamide
- 127-85-5
p-arsanilic acid monosodium salt
| Conditions | Yield |
|---|---|
| With water |
- 83473-10-3
2-chloro-N-(2-methyl-4-nitrophenyl)acetamide
- 127-85-5
p-arsanilic acid monosodium salt
| Conditions | Yield |
|---|---|
| With water |
- 333309-95-8
bromo-malonic acid di-p-toluidide
- 127-85-5
p-arsanilic acid monosodium salt
| Conditions | Yield |
|---|---|
| With ethanol |
- 861329-81-9
bromo-malonic acid bis-(4-bromo-anilide)
- 127-85-5
p-arsanilic acid monosodium salt
| Conditions | Yield |
|---|---|
| With ethanol |
| Conditions | Yield |
|---|---|
| With water |
- 96-34-4
methyl chloroacetate
- 127-85-5
p-arsanilic acid monosodium salt
- 5410-53-7
[4-(methoxycarbonylmethyl-amino)-phenyl]-arsonic acid
| Conditions | Yield |
|---|---|
| With methanol |
ARSANILIC ACID, MONOSODIUM SALT Chemical Properties
Product Name: Arsanilic acid, monosodium salt (CAS NO.127-85-5)
Molecular Formula: C6H6AsNNa2O3
Molecular Weight: 261.02g/mol
Mol File: 127-85-5.mol
Einecs: 204-869-9
Appearance: White crystalline, odorless powder
Water Solubility: Soluble in water
H-Bond Donor: 2
H-Bond Acceptor: 4
Product Categories: Organometallics; As (Arsenic) Compounds; Classes of Metal Compounds; Semimetal Compounds
ARSANILIC ACID, MONOSODIUM SALT Toxicity Data With Reference
| Organism | Test Type | Route | Reported Dose (Normalized Dose) | Effect | Source |
|---|---|---|---|---|---|
| dog | LDLo | subcutaneous | 5mg/kg (5mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. | |
| guinea pig | LDLo | subcutaneous | 70mg/kg (70mg/kg) | SENSE ORGANS AND SPECIAL SENSES: CHANGES IN COCHLEAR STRUCTURE OR FUNCTION: EAR BEHAVIORAL: MUSCLE WEAKNESS BEHAVIORAL: FOOD INTAKE (ANIMAL) | Acta Oto-Laryngologica. Vol. 82, Pg. 70, 1976. |
| mouse | LD50 | intravenous | 335mg/kg (335mg/kg) | Therapie. Vol. 2, Pg. 28, 1947. | |
| rabbit | LDLo | subcutaneous | 200mg/kg (200mg/kg) | "Abdernalden's Handbuch der Biologischen Arbeitsmethoden." Vol. 4, Pg. 1289, 1935. | |
| rat | LD50 | intravenous | 335mg/kg (335mg/kg) | Journal of the American Chemical Society. Vol. 68, Pg. 944, 1946. | |
| rat | LD50 | subcutaneous | 75mg/kg (75mg/kg) | Biochemische Zeitschrift. Vol. 184, Pg. 360, 1927. |
ARSANILIC ACID, MONOSODIUM SALT Consensus Reports
Arsenic and its compounds are on the Community Right-To-Know List.
ARSANILIC ACID, MONOSODIUM SALT Safety Profile
Poison by subcutaneous route. Can cause blindness. When heated to decomposition it emits very toxic fumes of As and NOx.
Safety Information of Arsanilic acid, monosodium salt (CAS NO.127-85-5):
Risk Statements: 26/27/28
26: Very Toxic by inhalation
27: Very Toxic in contact with skin
28: Very Toxic if swallowed
Safety Statements: 26-36/37/39
26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice
36: Wear suitable protective clothing
37: Wear suitable gloves
39: Wear eye/face protection
ARSANILIC ACID, MONOSODIUM SALT Standards and Recommendations
OSHA PEL: TWA 0.5 mg(As)/m3
ACGIH TLV: BEI: 35 μ (As)/L inorganic arsenic and methylated metabolites in urine
DOT Classification: 6.1; Label: KEEP AWAY FROM FOOD
ARSANILIC ACID, MONOSODIUM SALT Specification
Arsanilic acid, monosodium salt ,its CAS NO. is 127-85-5,the synonyms is Sodium 4-aminophenylarsonate ; Sodium arsanilate ; P-arsanilic acid sodium salt ; (4-Aminophenyl)arsonicacid,sodiumsalt[qr] ; (4-Aminophenyl)-arsonicacimonosodiumsalt ; Ai3-29289-x[qr] ; Anhydroussodiumarsanilate ; Anhydroussodiumarsanilate[qr] .
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