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Acid Blue 9

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Name

Acid Blue 9

EINECS 223-339-8
CAS No. 2650-18-2 Density 1.1666 (rough estimate)
PSA 202.99000 LogP 9.02170
Solubility Soluble in ethanol and water. Insoluble in vegetable oils. Melting Point 283 °C (dec.)(lit.)
Formula C37H34N2Na2O9S3 Boiling Point N/A
Molecular Weight 783.01 Flash Point N/A
Transport Information N/A Appearance blue violet powder
Safety Risk Codes N/A
Molecular Structure Molecular Structure of 2650-18-2 (Acid Blue 9) Hazard Symbols N/A
Synonyms

A.F. Blue No. 1;AF Blue No. 1;Acid Blue;AE-SF;Acilan Turquoise Blue AE;Alphazurine FGND;Bleu Brilliant FCF;C.I. 42090;C.I. Acid Blue 9, diammonium salt;C.I. Direct Brown 78, Diammonium Salt;CI 42090;CI Acid Blue 9, diammonium salt;CI Direct Brown 78, diammonium salt;Calcocid Blue EG;Caswell No. 007A;EPA Pesticide Chemical Code 110301;Erioglaucine (Biological Stain);Erioglaucine A;Fenazo Blue XR;HSDB 5890;Japan Blue 205;Kiton Pure Blue L;NSC 4318;Neptune Blue BRA;Concentration;

 

Acid Blue 9 Chemical Properties

Chemistry informtion about Acid Blue 9 (CAS NO.2650-18-2) is:
IUPAC Name: Diazanium 2-[[4-[Ethyl-[(3-Sulfonatophenyl)Methyl]Amino]Phenyl]-[4-[Ethyl-[(3-Sulfonatophenyl)Methyl]Azaniumylidene]Cyclohexa-2,5-Dien-1-Ylidene]Methyl]Benzenesulfonate
Synonyms: Acilan Turquoise Blue AE ; Aizen Brilliant Blue FCF ; Alphazurine (indicator) ; Alphazurine FG ; Brilliant Blue ; Brilliant Blue Lake ; Bucacid Azure Blue ; Ammonium, ethyl(4-(p-(ethyl(m-sulfobenzyl)amino)-alpha-(o-sulfophenyl)benzylidene)-2,5-cyclohexadien-1-ylidene)(m-sulfobenzyl)-, hydroxide, inner salt, diammonium salt ; Diammonio(ethyl)(4-((4-(ethyl(3-sulphonatobenzyl)amino)phenyl)(2-sulphonatophenyl)methylene)cyclohexa-2,5-dien-1-ylidene)(3-sulphonatobenzyl)ammonium
Molecular Formula: C37H34N2Na2O9S3
Molecular Weight: 792.85
EINECS: 223-339-8
Melting Point: 283 °C (dec.)(lit.)
Following is the molecular structure of C.I. Acid Blue 9 (CAS NO.2650-18-2) is:

Acid Blue 9 Uses

 Acid Blue 9 (CAS NO.2650-18-2) is also used in soaps, shampoos, and other hygiene and cosmetics applications. In soil science, Brilliant Blue is applied in tracing studies to visualize infiltration and water distribution in the soil. It is used as the stain in Listerine's Agent Cool Blue mouthwash. A research study at the University of Rochester Medical Centre, New York, are investigating Acid Blue 9 efficacy in treating spinal cord injuries. Tests in rats have shown that IV administration of the dye shortly after spinal trauma has the effect of blocking the natural release of a chemical (adenosine triphosphate) that causes damage to healthy cells surrounding a spinal lesion. Research continues into safety and the effective administration to humans, with one potential barrier being that the treatment has the effect of temporarily turning the skin bright blue.

Acid Blue 9 Toxicity Data With Reference

Organism Test Type Route Reported Dose (Normalized Dose) Effect Source
human LDLo intravenous 33ug/kg (0.033mg/kg) behavioral: muscle contraction or spasticity) lungs, thorax, or respiration: dyspnea "Toxicology of Drugs and Chemicals," Deichmann, W.B., New York, Academic Press, Inc., 1969Vol. -, Pg. 87, 1969

Acid Blue 9 Safety Profile

Safty information about Acid Blue 9 (CAS NO.2650-18-2) is:
WGK Germany: 3
RTECS: BQ4725000

Acid Blue 9 Specification

 Acid Blue 9 (CAS NO.2650-18-2) is a blue powder. It may exist as disodium, diammonium or monoammonium-monosodium salt. It is a colorant for foods and other substances to induce a color change. It is denoted by E number E133 and has a color index of 42090. It has the appearance of a reddish-blue powder. It is soluble in water, and the solution has a maximum absorption at about 628 nanometer. Acid Blue 9 has previously been banned in Austria, Belgium, Denmark, France, Germany, Greece, Italy, Norway, Spain, Sweden, and Switzerland among others but has been certified as a safe food additive in the EU and is today unbanned in most of the countries. It has the capacity for inducing an allergic reaction in individuals with pre-existing moderate asthma. In the United States production exceeds 1 million pounds annually, and daily consumption is around 16 mg per person.It is one of the colorants that the Hyperactive Children's Support Group and the Feingold Association recommends to be eliminated from the diet of children. After extensive testing, the National Institutes of Health concluded that color additives do not cause hyperactivity.

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