IARC Cancer Review: Animal Inadequate Evidence IMEMDT    IARC Monographs on the Evaluation of Carcinogenic Risk of Chemicals to Man . 15 (1977),p. 183.(World Health Organization, Internation Agency for Research on Cancer,Lyon, France.: ) (Single copies can be ordered from WHO Publications Centre U.S.A., 49 Sheridan Avenue, Albany, NY 12210) . EPA Genetic Toxicology Program. Reported in EPA TSCA Inventory.

The IUPAC name of Bromoeosine is disodium 2-(2,4,5,7-tetrabromo-3-oxido-6-oxoxanthen-9-yl)benzoate. With the CAS registry number 17372-87-1, it is also named as Acid red 87; Eosine Yellowish. The poduct's categories are dyes and pigments; organics; hematology and histology; hematology stains; stains and dyes; fluorescent labels; fluorescent probes, labels, particles and stains; other fluorescent labels. It is brownish-red powder which is stable and incompatible with strong oxidizing agents. When heated to decomposition Bromoeosine emits very toxic fumes of Br^- and Na₂O. In addition, the storage environment should be ventilate, low-temperature and dry.

The other characteristics of this product can be summarized as: (1)ACD/LogP: 6.36; (2)# of Rule of 5 Violations: 2; (3)ACD/LogD (pH 5.5): 4.18; (4)ACD/LogD (pH 7.4): 2.26; (5)ACD/BCF (pH 5.5): 264.1; (6)ACD/BCF (pH 7.4): 3.2; (7)ACD/KOC (pH 5.5): 452.21; (8)ACD/KOC (pH 7.4): 5.48; (9)#H bond acceptors: 5; (10)#H bond donors: 2; (11)#Freely Rotating Bonds: 3; (12)Enthalpy of Vaporization: 105.14 kJ/mol; (13)Vapour Pressure: 1.49E-19 mmHg at 25°C; (14)Rotatable Bond Count: 1; (15)Exact Mass: 691.67032; (16)MonoIsotopic Mass: 687.674413; (17)Topological Polar Surface Area: 89.5; (18)Heavy Atom Count: 31; (19)Complexity: 797.

Uses of Bromoeosine: It is acid dye which can be used to stain cytoplasm, collagen and muscle fibers for examination under the microscope. And it is also used as adsorption indicator.

When you are using this chemical, please be cautious about it as the following:
It is highly flammable, so people should keep away from sources of ignition. And it is toxic by inhalation, in contact with skin and if swallowed, so people must avoid contact with skin and eyes. In addition, Bromoeosine is harmful to aquatic organisms, may cause long-term adverse effects in the aquatic environment. In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. If you want to contact this product, you must wear suitable protective clothing, gloves and eye/face protection. In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.) Avoid release to the environment and keep container tightly closed.

People can use the following data to convert to the molecule structure.
1. SMILES: [Na+].[Na+].[O-]C(=O)c4ccccc4C=1c3cc(Br)c([O-])c(Br)c3OC=2C=1\C=C(\Br)C(=O)C=2Br;
2. InChI: InChI=1/C20H8Br4O5.2Na/c21-11-5-9-13(7-3-1-2-4-8(7)20(27)28)10-6-12(22)17(26)15(24)19(10)29-18(9)14(23)16(11)25;;/h1-6,25H,(H,27,28);;/q;2*+1/p-2.

The following are the toxicity data which has been tested.

Organism	Test Type	Route	Reported Dose (Normalized Dose)	Effect	Source
mouse	LD50	oral	2344mg/kg (2344mg/kg)		Eastern Pharmacist. Vol. 24, Pg. 125, 1981.
rabbit	LDLo	intravenous	300mg/kg (300mg/kg)		International Journal of Leprosy and Other Mycobacterial Diseases. Vol. 2, Pg. 257, 1934.
rat	LDLo	intraperitoneal	500mg/kg (500mg/kg)		International Journal of Leprosy and Other Mycobacterial Diseases. Vol. 2, Pg. 257, 1934.