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| Name |
Acridin-9-amine hydrochloride |
EINECS | 205-145-5 |
| CAS No. | 134-50-9 | Density | 1.268g/cm3 |
| PSA | 38.91000 | LogP | 4.35340 |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C13H10 N2 . Cl H | Boiling Point | 413.5°Cat760mmHg |
| Molecular Weight | 230.71 | Flash Point | 233.2°C |
| Transport Information | N/A | Appearance | Pale yellow crystals. One of the most highly fluorescent substances. |
| Safety | Poison by ingestion. Mutation data reported. See also AMINES. When heated to decomposition it emits very toxic fumes of HCl and NOx. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | N/A |
| Synonyms |
9-Acridinamine,monohydrochloride (9CI); Acridine, 9-amino-, monohydrochloride (8CI);9-Aminoacridine hydrochloride; 9-Aminoacridine monohydrochloride; Acramineyellow; Aminacrine hydrochloride; Monacrin hydrochloride |
Acridin-9-amine hydrochloride Synthetic route
- 134-50-9
acridin-9-amine hydrochloride
- 110166-26-2
aminacrine
| Conditions | Yield |
|---|---|
| With sodium hydroxide In water; ethyl acetate for 0.25h; Concentration; Reagent/catalyst; Solvent; | 100% |
| Conditions | Yield |
|---|---|
| In ethanol; water for 0.25h; Heating; | 99% |
- 52824-42-7
N-(7-bromoheptyl)phthalimide
- 134-50-9
acridin-9-amine hydrochloride
| Conditions | Yield |
|---|---|
| With potassium hydroxide In dimethyl sulfoxide at 20℃; for 12h; | 74% |
| Conditions | Yield |
|---|---|
| In pyridine at 70℃; for 24h; | 67.8% |
- 82484-59-1
4-bis-(β-chloroethyl)aminophenyl isocyanate
- 134-50-9
acridin-9-amine hydrochloride
- 1036724-69-2
1-acridin-9-yl-3-{4-[bis(2-chloroethyl)amino]phenyl}urea
| Conditions | Yield |
|---|---|
| With triethylamine In N,N-dimethyl-formamide at 20℃; for 18h; | 60% |
- 93667-91-5
2-(9-bromononyl)isoindoline-1,3-dione
- 134-50-9
acridin-9-amine hydrochloride
| Conditions | Yield |
|---|---|
| With potassium hydroxide In dimethyl sulfoxide at 20℃; for 12h; | 55.5% |
| Conditions | Yield |
|---|---|
| With 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine In dimethyl sulfoxide at 20 - 40℃; for 49h; | 53% |
| Stage #1: acridin-9-amine hydrochloride With triethylamine In water; dimethyl sulfoxide at 20℃; for 1h; Stage #2: 3-Carboxyphenylboronic acid With 1,8-diazabicyclo[5.4.0]undec-7-ene In water; dimethyl sulfoxide at 40℃; for 48h; | 53% |
- 17702-83-9
N-8-bromooctylphthalimide
- 134-50-9
acridin-9-amine hydrochloride
| Conditions | Yield |
|---|---|
| With potassium hydroxide In dimethyl sulfoxide at 20℃; for 12h; | 18.5% |
- 134-50-9
acridin-9-amine hydrochloride
A
- 23045-35-4
2-nitro-9-aminoacridine
B
- 157996-62-8
9-amino-2,7-dinitroacridine
| Conditions | Yield |
|---|---|
| With sodium nitrate; sulfuric acid at 0℃; for 0.5h; | A 9.6% B 15% |
| With sodium nitrate; sulfuric acid at 0℃; for 0.5h; | A 9.6% B 15% |
- 24566-79-8
2-(6-bromohexyl)isoindole-1,3-dione
- 134-50-9
acridin-9-amine hydrochloride
| Conditions | Yield |
|---|---|
| With potassium hydroxide In dimethyl sulfoxide at 20℃; for 12h; | 15% |
Acridin-9-amine hydrochloride Chemical Properties
IUPAC Name: Acridin-9-amine hydrochloride
The MF of Acridin-9-amine hydrochloride (CAS NO.134-50-9) is C13H11ClN2.
The MW of Acridin-9-amine hydrochloride (CAS NO.134-50-9) is 230.69.
Synonyms of Acridin-9-amine hydrochloride (CAS NO.134-50-9): 9-Aminoacridine hydrochloride ; Acridin-9-amine hydrochloride ; 5-Aminoacridine hydrochloride
Apperance: Pale yellow crystals.One of the most highly fluorescent substances
Flash Point: 233.2 °C
Boiling Point: 413.5 °C
EINECS: 205-145-5
Acridin-9-amine hydrochloride Uses
Acridin-9-amine hydrochloride (CAS NO.134-50-9) is used experimentally as a probe for biological membranes and dna.
Acridin-9-amine hydrochloride Production
Acridin-9-amine hydrochloride forms from treatment of 9-aminoacridine with hydrogen chloride. It is amphoteric (reacts both as a weak acid and as a weak base).
Acridin-9-amine hydrochloride Toxicity Data With Reference
| 1. | mmo-sat 10 µg/plate | KSRNAM Kiso to Rinsho. Clinical Report. 16 (1982),6240. | ||
| 2. | mma-sat 50 µg/plate | KSRNAM Kiso to Rinsho. Clinical Report. 17 (1983),70. | ||
| 3. | dnr-esc 20 µL/disc | MUREAV Mutation Research. 97 (1982),1. | ||
| 4. | dnr-bcs 20 µL/disc | MUREAV Mutation Research. 97 (1982),1. | ||
| 5. | cyt-ham:lng 600 µg/L | GMCRDC Gann Monograph on Cancer Research. 27 (1981),95. | ||
| 6. | dnd-man:lym 10 pph | BIPMAA Biopolymers. 11 (1972),2537. | ||
| 7. | orl-mus LD50:78 mg/kg | 29ZVAB Handbook of Analytical Toxicology ,Sunshine, I., ed., Cleveland, OH.: Chemical Rubber Co.,1969,7 |
Acridin-9-amine hydrochloride Consensus Reports
Reported in EPA TSCA Inventory. EPA Genetic Toxicology Program.
Acridin-9-amine hydrochloride Safety Profile
Poison by ingestion. Mutation data reported. See also AMINES. When heated to decomposition it emits very toxic fumes of HCl and NOx.Safety information of Acridin-9-amine hydrochloride (CAS NO.134-50-9):
Safety Statements
22 Do not breathe dust
24/25 Avoid contact with skin and eyes
WGK Germany 3
Acridin-9-amine hydrochloride Specification
Flash point data for Acridin-9-amine hydrochloride is not available, but Acridin-9-amine hydrochloride is probably combustible.
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