Basic Information | Post buying leads | Suppliers |
Name |
Amidefrine mesylate |
EINECS | N/A |
CAS No. | 1421-68-7 | Density | g/cm3 |
PSA | 149.56000 | LogP | 2.44040 |
Solubility | N/A | Melting Point |
207-209° |
Formula | C10H16N2O3S•CH4O3S | Boiling Point | 430.7°Cat760mmHg |
Molecular Weight | 340.45 | Flash Point | 214.3°C |
Transport Information | N/A | Appearance | N/A |
Safety | Poison by ingestion, intraperitoneal, intravenous, and intradermal routes. Moderately toxic by subcutaneous route. An eye irritant. When heated to decomposition it emits very toxic fumes of NOx and SOx. A vasoconstrictor and nasal decongestant. See also SULFONATES. | Risk Codes | N/A |
Molecular Structure | Hazard Symbols | N/A | |
Synonyms |
amidephrine mesylate |
Molecule structure of Amidefrine mesylate (CAS NO.1421-68-7):
IUPAC Name: N-[4-[1-Hydroxy-2-(methylamino)ethyl]phenyl]methanesulfonamide; methanesulfonic acid
Molecular Weight: 340.4163 g/mol
Molecular Formula: C11H20N2O6S2
Boiling Point: 430.7 °C at 760 mmHg
Flash Point: 214.3 °C
Enthalpy of Vaporization: 72.34 kJ/mol
Vapour Pressure: 3.48E-08 mmHg at 25 °C
H-Bond Donor: 4
H-Bond Acceptor: 8
Rotatable Bond Count: 5
Exact Mass: 340.076278
MonoIsotopic Mass: 340.076278
Topological Polar Surface Area: 133
Heavy Atom Count: 21
Complexity: 384
Canonical SMILES: CNCC(C1=CC=C(C=C1)NS(=O)(=O)C)O.CS(=O)(=O)O
InChI: InChI=1S/C10H16N2O3S.CH4O3S/c1-11-7-10(13)8-3-5-9(6-4-8)12-16(2,14)15;1-5(2,3)4/h3-6,10-13H,7H2,1-2H3;1H3,(H,2,3,4)
InChIKey: VNHHFNWFTCUMGQ-UHFFFAOYSA-N
1. | eye-rbt 10 mg MLD | TXAPA9 Toxicology and Applied Pharmacology. 23 (1972),589. | ||
2. | orl-rat LD50:13 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 23 (1972),589. | ||
3. | ipr-rat LD50:5 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 23 (1972),589. | ||
4. | orl-mus LD50:2284 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 23 (1972),589. | ||
5. | ipr-mus LD50:780 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 23 (1972),589. | ||
6. | scu-mus LD50:1990 mg/kg | IJNEAQ International Journal of Neuropharmacology. 4 (1965),219. | ||
7. | ivn-mus LD50:190 mg/kg | IJNEAQ International Journal of Neuropharmacology. 4 (1965),219. | ||
8. | ipr-dog LD50:4800 µg/kg | IJNEAQ International Journal of Neuropharmacology. 4 (1965),219. | ||
9. | ivn-dog LD50:1400 µg/kg | TXAPA9 Toxicology and Applied Pharmacology. 23 (1972),589. | ||
10. | orl-cat LDLo:2 mg/kg | TXAPA9 Toxicology and Applied Pharmacology. 23 (1972),589. | ||
11. |
Poison by ingestion, intraperitoneal, intravenous, and intradermal routes. Moderately toxic by subcutaneous route. An eye irritant. When heated to decomposition it emits very toxic fumes of NOx and SOx. A vasoconstrictor and nasal decongestant. See also SULFONATES.
Amidefrine mesylate (CAS NO.1421-68-7) is also named as (2-Methylamine-1-hydroxyethyl)methanesulfonanilide methanesulfonate ; 3'-(1-Hydroxy-2-(methylamino)ethyl)methanesulfonanilide methanesulfonate ; 3'-(1-Hydroxy-2-(methylamino)ethyl)methanesulfonanilide monomethanesulfonate (salt) ; 3'-(2-(Methylamino)-l-hydroxyethyl)methanesulfonanilide methanesulfonate ; Amideferini mesilas ; Amideferini mesilas [INN-Latin] ; Amidefrini mesilas ; Amidefrini mesilas [INN-Spanish] ; Amidefrini mesylas ; Amidephrine mesylate ; Amidephrine monomethanesulfonate ; Dricol ; Fentrinol ; MJ 5190 ; Mesilate d'amidefrine ; Mesilate d'amidefrine [INN-French] ; Mesylate d'amideferine ; Methanesulfonamide, N-(3-(1-hydroxy-2-(methylamino)ethyl)phenyl)-, monomethanesulfonate (salt) ; Methanesulfonamide, N-(3-(1-hydroxy-2-(methylamino)ethyl)phenyl)-, monomethanesulfonate salt ; Methanesulfonanilide, 3'-(1-hydroxy-2-(methylamino)ethyl)-, methanesulfonate ; Nalde ; Product 5190 ; UNII-S3IG39T94B . Amidefrine mesylate (CAS NO.1421-68-7) is highly toxic. It is flammable. It will produce toxic nitrogen oxide and sulfur oxide fumes when buring. So the storage environment should be ventilate, low-temperature and dry.