- Amphotericin B
- Amphotericin b, methyl ester hydrochloride
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| Name |
Amphotericin b, methyl ester hydrochloride |
EINECS | N/A |
| CAS No. | 35375-29-2 | Density | N/A |
| PSA | N/A | LogP | N/A |
| Solubility | N/A | Melting Point |
N/A |
| Formula | C47H75NO20•ClH | Boiling Point | N/A |
| Molecular Weight | 1010.69 | Flash Point | N/A |
| Transport Information | N/A | Appearance | N/A |
| Safety | Poison by intravenous route. See also ESTERS. Moderately toxic by intraperitoneal route. When heated to decomposition it emits very toxic fumes of NOx and HCl. | Risk Codes | N/A |
| Molecular Structure |
|
Hazard Symbols | 3 |
| Synonyms |
N/A |
Amphotericin b, methyl ester hydrochloride Chemical Properties
Molecular Structure of Amphotericin b, methyl ester hydrochloride (CAS NO. 35375-29-2):
.png)
IUPAC Name: methyl (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-
33-[(2R,3S,4S,5S,6R)-4-amino-3,5-dihydroxy-6-methyloxan-2-yl]oxy-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylate hydrochloride
Empirical Formula: C48H76ClNO17
Molecular Weight: 974.5665
Flash Point: 620.6 °C
Enthalpy of Vaporization: 183.21 kJ/mol
Boiling Point: 1102.6 °C at 760 mmHg
Vapour Pressure: 0 mmHg at 25°C
Amphotericin b, methyl ester hydrochloride Toxicity Data With Reference
| 1. | ipr-mus LD50:1320 mg/kg | SCIEAS Science. 179 (1973),584. | ||
| 2. | ivn-mus LD50:75 mg/kg | 85ERAY Antibiotics: Origin, Nature, and Properties. 2 (1978),1019. | ||
| 3. | ivn-dog LD50:48 mg/kg | SCIEAS Science. 179 (1973),584. |
Amphotericin b, methyl ester hydrochloride Safety Profile
Poison by intravenous route. See also ESTERS. Moderately toxic by intraperitoneal route. When heated to decomposition it emits very toxic fumes of NOx and HCl.
Amphotericin b, methyl ester hydrochloride Specification
Amphotericin b, methyl ester hydrochloride ,its CAS number is 35375-29-2,it can be called AME hydrochloride and Amphotericin B .
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