Molecular Formula: C₅₀H₇₃N₁₅O₁₁
Molar mass: 1060.21 g/mol
EINECS: 227-781-2
Density: 1.49 g/cm³
Index of Refraction: 1.693
Storage temp: −20°C
Solubility: H2O: >40 mg/mL
Structure of Bradykinin (58-82-2):
      

 Bradykinin (58-82-2) was discovered in 1948 by three Brazilian physiologists and pharmacologists working at the Instituto Biológico, in São Paulo, Brazil.The discovery was part of a continuing study on circulatory shock and proteolytic enzymes related to the toxicology of snake bites, started by Rocha e Silva as early as 1939.they discovered the powerful hypotensive effects of bradykinin in animal preparations. It was detected in the blood plasma of animals after the addition of venom extracted from the Bothrops jararaca, brought by Rosenfeld from the Butantan Institute. Bradykinin was to prove a new autopharmacological principle, i.e., a substance that is released in the body by a metabolic modification from precursors. According to B.J. Hagwood, Rocha e Silva's biographer, "The discovery of bradykinin has led to a new understanding of many physiological and pathological phenomena including circulatory shock induced by venoms and toxins."

The kinin-kallikrein system makes Bradykinin (58-82-2) by proteolytic cleavage of its kininogen precursor, high-molecular-weight kininogen, by the enzyme kallikrein.

Experimental teratogenic and reproductive effects. Mutation data reported. When heated to decomposition it emits toxic fumes of NO_x.
 

Safety Statements:
22:  Do not breathe dust
24:  Avoid contact with skin
25:  Avoid contact with eyes

 Bradykinin (58-82-2) also can be Synthetic bradykinin .And it is a peptide that could cause blood pressure to lower.It is a physiologically and pharmacologically active peptide of the kinin group of proteins, consisting of nine amino acids.As a class of drugs called ACE inhibitors, which are used to lower blood pressure, increase bradykinin further lowering blood pressure. Bradykinin works on blood vessels through the release of prostacyclin, nitric oxide, and Endothelium-Derived Hyperpolarizing Factor.